Hawaiian, asian american, and pacific islander (HAAPI) coordinating center

Active Cooperative Agreement Awarded Last action

Award ID
U24HL169645
Recipient
Awarding agency
Obligated
$14,708,639

Award facts

Assistance listing
93.310 Trans-NIH Research Support
Completion date 65% complete
Funding agency
Office of the Director National Institutes of Health, Department of Health and Human Services
Place of performance
Seattle, WA 98109, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
People of asian, hawaiian, or pacific islander (ASA-NHPI) ancestry, while representing 7.7% of the US population, have been largely underrepresented from NIH-funded prospective epidemiologic studies. As a result, there are large gaps in our knowledge of the burden and causes of cardiovascular, metabolic, and mental health disorders in these populations. Individuals of these backgrounds have experienced, to varying degrees, the barriers, stresses, and stereotyping experienced by other minorities while also having challenges that are unique to them. Understanding the heterogeneity of their lifestyles and societal and environmental circumstances, as well as their ancestry, is a critical first step in determining their health needs and how to address them. The heterogeneity in these populations, followed longitudinally and contrasted with other populations, may add unique insights into the etiology of both physical and mental health conditions. In this application for the hawaiian, asian american, and pacific islander coordinating center (HAAPI-CC), we propose to: (1) bring exceptional scientific, statistical, and cultural expertise to the effort of assessing the physical and mental health and their determinants in people of hawaiian, asian, and pacific islander ancestry; (2) provide the operational, data science, and biorepository infrastructure and leadership to support the scientific priorities of the cohort and stimulate and enhance ancillary study opportunities broadly; (3) coordinate and support clinical or community field center (CCFC) activities to enhance recruitment and retention and broader community engagement; and (4) enhance career development of early stage investigators, particularly those from under-represented backgrounds. Through this effort, we can estimate the prevalence of cardiovascular diseases and risk factors and mental health conditions, study their interplay and trajectories over time, and examine associations with novel exposures derived from data linkages and biospecimens. We anticipate leading a number of ancillary studies to obtain additional rich data from novel sources (wearables, mhealth, genomics, proteomics, metabolomics, microbiome, cardiac and brain imaging). Through these efforts, we and our CCFC colleagues, will advance the knowledge of the health conditions of asian, hawaiian, and pacific islanders and provide the infrastructure for deeper understanding of their biological, environmental, and sociological underpinnings. ,

Transactions

Action Obligated Date
Amendment $0
Amendment $199,820
Amendment Mosaaic electronic health records administrative supplement $279,063
Amendment $149,836
Amendment $1,586,327
Amendment $299,987
Amendment Mosaaic cognitive assessment reading center administrative supplement $289,470
Amendment $0
Amendment Multi-ethnic observational study in american asian and pacific islander communities (MOSAAIC) administrative supplement for pbmcs and RNA paxgene $0
Amendment $0
Amendment $0
Amendment $0
Amendment Mosaaic cognitive assessment reading center administrative supplement $0
Amendment $102,473
Amendment Multi-ethnic observational study in american asian and pacific islander communities (MOSAAIC) administrative supplement for pbmcs and RNA paxgene $372,945
Amendment $3,590,925
Amendment Multi-ethnic observational study in american asian and pacific islander communities (MOSAAIC) administrative supplement for pbmcs and RNA paxgene $144,443
Amendment $0
Amendment $0
Amendment Multi-ethnic observational study in american asian and pacific islander communities (MOSAAIC) administrative supplement for pbmcs and RNA paxgene $0
Amendment $99,992
Original award $99,992
Show all 22

Subawards

Subrecipient Amount Awarded
The Leland Stanford Junior University NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to Clinical/Community Field Centers (CCFCs) via a capitation reimbursement model… $215,600
The Leland Stanford Junior University NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) to reimburse for PBMC… $40,766
Regents Of The University Of Minnesota Dr. Thyagarajan will provide oversight for this admin supplement. The scope of work includes supplies and storage for 3167 PBMC and Paxgene RNA. $129,484
Regents Of The University Of Minnesota For this competitive supplement, Dr. Thyagarajan will provide oversight for this scope of work for participants age 65+: Provide biospecimen kits for sample… $118,936
University Of Hawaii NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to Clinical/Community Field Centers (CCFCs) via a capitation reimbursement model… $219,100
University Of Pittsburgh - Of The Commonwealth System Of Higher Education For this competitive supplement, Dr. Celedón will provide oversight for this scope of work for participants age 65+: 1. Supervise the transfer, quality… $36,319
The Leland Stanford Junior University For this competitive supplement, Dr. Henderson will provide oversight for this scope of work for participants age 65+: Advise on aging measures with a focus… $58,109
Temple University-Of The Commonwealth System Of Higher Education NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to Clinical/Community Field Centers (CCFCs) via a capitation reimbursement model… $124,264
Regents Of The University Of Minnesota Dr. Thyagarajan will provide oversight for this admin supplement. His effort remains on the main grant. The scope of work includes additional funds for storage,… $51,471
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Dr. Celedon is providing oversight for this admin supplement. University of Pittsburgh will provide spirometers and spirometry supplies to the CCFCs in years… $136,761
New York University NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to Clinical/Community Field Centers (CCFCs) via a capitation reimbursement model… $237,300
Wake Forest University Health Sciences For this competitive supplement, Dr. Soliman will provide oversight for this scope of work for participants age 65+: The EPICARE ECG Reading Center will provide… $41,166
The University Of Chicago NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to Clinical/Community Field Centers (CCFCs) via a capitation reimbursement model… $229,600
The Institute For Cancer Research $157,920
The University Of Chicago NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) to reimburse for PBMC… $51,906
University Of Hawaii $49,533
The University Of Chicago NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) via a capitation reimbursement… $733,960
University Of Hawaii $708,960
The Institute For Cancer Research $326,100
New York University NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) to reimburse for PBMC… $53,647
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Dr. Celedón, working with Drs. Rosser and Han and other members of the clinical center committee, will prepare and test a database and plan data management… $249,651
Temple University-Of The Commonwealth System Of Higher Education NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) via a capitation reimbursement… $407,860
The Leland Stanford Junior University $778,760
University Of Washington NHLBI will distribute funds to the Coordinating Center (CC) to be distributed toFor this administrative supplement, Dr. Chan will oversee the data analysis of… $91,703
New York University NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) via a capitation reimbursement… $733,960
Wake Forest University Health Sciences Dr. Soliman will oversee the EPICARE ECG Reading Center and will provide detailed measurements and classification of ECG abnormalities from approximately 10,000… $179,616
The Regents Of The University Of California. San Francisco As the Steering Committee (SC) Chair, Dr. Kanaya will chair the monthly SC meeting, attend weekly Executive Committee (EC), and NHLBI/CC check-in meetings. $68,381
Regents Of The University Of Minnesota Dr. Thyagarajan will provide oversight for this scope of work. • Maintain instrumentation and perform methodology for the following analytical tests: total… $668,944
University Of Washington Dr. Chan is Professor of Department of Biostatistics and Department of Health Systems and Population Health at the University of Washington, and an Affiliate… $381,912
Albert Einstein College Of Medicine Dr. Kaplan will apply his experience leading the Einstein Field Center in the NHLBI Study of Latinos (SOL), the largest long-term study of Hispanics ever… $66,153
University Of Hawaii Personnel: Dr. Mau (contact PI) will provide additional 3% FTE to oversee community engagement activities to recruit and enroll NHPI participants. A Community… $80,787
The University Of Chicago NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) via a capitation reimbursement… $134,400
The Leland Stanford Junior University $134,400
University Of Hawaii $112,000
Regents Of The University Of Minnesota Dr. Thyagarajan will provide oversight for this admin supplement. The scope of work includes supplies and storage for the PAXgene RNA specimens for all… $136,349
Regents Of The University Of Minnesota Dr. Thyagarajan will provide oversight for this scope of work. • Maintain instrumentation and perform methodology for the following analytical tests:… $221,244
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Dr. Celedón is providing oversight for this admin supplement. University of Pittsburgh will provide spirometers and spirometry supplies to the CCFCs in years… $83,273
Temple University-Of The Commonwealth System Of Higher Education NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) via a capitation reimbursement… $76,160
Regents Of The University Of Minnesota Dr. Thyagarajan will provide oversight for this admin supplement. The scope of work includes additional funds for supplies, storage, shipping, and lipid… $50,797
The Institute For Cancer Research NHLBI will distribute funds to the Coordinating Center (CC) to be distributed to each Clinical or Community Field Centers (CCFCs) via a capitation reimbursement… $91,840
New York University $123,200
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Dr. Celedón, working with Drs. Rosser and Han and other members of the clinical center committee, will prepare and test a database and plan data management… $169,523
The Regents Of The University Of California. San Francisco As the Steering Committee (SC) Chair, Dr. Kanaya will chair the monthly SC meeting, attend weekly Executive Committee (EC), and NHLBI/CC check-in meetings. $68,620
Wake Forest University Health Sciences Dr. Soliman will oversee the EPICARE ECG Reading Center and will provide detailed measurements and classification of ECG abnormalities from approximately 10,000… $84,538
University Of Washington Dr. Chan is Professor of Department of Biostatistics and Department of Health Systems and Population Health at the University of Washington, and an Affiliate… $491,506
Albert Einstein College Of Medicine Dr. Kaplan will apply his experience leading the Einstein Field Center in the NHLBI Study of Latinos (SOL), the largest long-term study of Hispanics ever… $113,922
University Of Washington Dr. Chan is Professor of Department of Biostatistics and Department of Health Systems and Population Health at the University of Washington, and an Affiliate… $65,952
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Participate in the monthly Clinical Assessment Committee meetings and help to set expectations about equipment and procedures and work with PI to develop the… $33,159
Show all 48

Quick answers

Who received award U24HL169645?

U24HL169645 was awarded to Fred Hutchinson Cancer Center by National Heart Lung and Blood Institute (National Institutes of Health) on August 15, 2023.

How much is award U24HL169645 worth?

$14,708,639 has been obligated on U24HL169645.

Which agency awarded U24HL169645?

National Heart Lung and Blood Institute (National Institutes of Health) awarded U24HL169645, with funding from Office of the Director (National Institutes of Health).

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