This proposal for a translational research institute is submitted on behalf of a consortium of non-profit academic institutions in response to NASA C

Active Cooperative Agreement Awarded Last action

Award ID
NNX16AO69A
Recipient
Awarding agency
Obligated
$139,591,380

Award facts

Assistance listing
43.003 Exploration
Completion date 84% complete
Place of performance
Houston, TX 77030, USA

Award details come from USAspending.gov.

Transactions

Action Federal Non-federal Date
Amendment $5,275,169 $0
Amendment The establishment of the human research program translational research institute $1,700,000 $0
Amendment $2,500,000 $0
Amendment $500,000 $0
Amendment $3,777,231 $0
Amendment $1,000,000 $0
Amendment The establishment of the human research program translational research institute $600,000 $0
Amendment $1,000,000 $0
Amendment $1,000,000 $0
Amendment $2,992,211 $0
Amendment $5,242,543 $0
Amendment $251,848 $0
Amendment $5,118,137 $0
Amendment $5,000,000 $0
Amendment $5,000,000 $0
Amendment $121,000 $0
Amendment $1,000 $0
Amendment Translational research institute $2,650,000 $0
Amendment $2,317,000 $0
Amendment $2,400,000 $0
Amendment $1,000,000 $0
Amendment $7,049,198 $0
Amendment $400,000 $0
Amendment $117,000 $0
Amendment $0 $0
Amendment $0 $0
Amendment $174,726 $174,726
Amendment Translational research institute $1,300 $0
Amendment $1,500,000 $0
Amendment $70,854 $0
Amendment $3,500,000 $0
Amendment -$64,999 $0
Amendment $2,000,000 $0
Amendment $1,465,000 $0
Amendment $3,600,000 $0
Amendment $115,280 $0
Amendment $3,266,065 $0
Amendment $2,700,000 $0
Amendment $7,000,000 $0
Amendment $2,686,440 $0
Amendment $3,355,000 $0
Amendment $1,742,877 $0
Amendment $2,250,000 $0
Amendment $0 $0
Amendment $4,293,000 $0
Amendment -$150,000 $0
Amendment $6,206,000 $0
Amendment $0 $0
Amendment $3,000,000 $0
Amendment $6,000,000 $0
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Subawards

Subrecipient Amount Awarded
Texas A & M University System Health Science Center Y1 AGREE $90,000 Commercialized space travel exposes non-professional astronauts with potential aging health issues to the risk of vision complications known as… $90,000
The General Hospital Corporation The Principal Investigator for Massachusetts General Hospital (MGH), Dr. Gary Strangman, will serve as a Scientific Lead for the Translational Research… $249,363
The Leland Stanford Junior University The EXPAND database contains rich multi-modal data from commercial spaceflight missions including physiologic, survey, omics, environmental, and cognitive… $510,852
Snke, Inc. Y1 AMEND ($58.55) The primary goal of this project is to leverage simulated imagery to train a machine learning (ML) algorithm and assess the detection of… $149,935
Blue Origin Texas, LLC Y4 Amend ($62,204) Y4 Amend $236,217 Y3 Amend $46,393 Y3 Amend $148,272 Y2 Amend $132,393 Y1 Amend $149,610 1. Conduct internal and external stakeholder… $650,681
The Leland Stanford Junior University Y3 AWARD $152,864.17 Y2 AWARD $114,675.00 Y1 AWARD $73,209.63 The Stanford team will be responsible for two critical aspects: 1) The molecular analysis of the… $340,749
Space Exploration Technologies Corp. Y4 Amend $285,725 Y3 Amend $171,705 Y3 AMEND $452,779 Y2 Amend $433,599 Y1 Agree $373,850 Goals and Objectives The goals of this proposal have been developed… $1,717,658
The Trustees Of The University Of Pennsylvania Y5 AMEND $221,345 Y4 AMEND $229,672 Y3 AMEND $298,931 Y2 AMEND $99,980 Y1 AGREE $149,750 The proposed research will be performed on two commercial crew flights:… $999,678
Massachusetts Institute Of Technology Y9 Amend ($67,493.79) Y10 AMEND $233,972 Y9 AMEND ($14,228.80) Y9 AMEND $661,396 Y8 AMEND $350,000 Y7 AMEND(DE-OB) ($6,525) Y8 AMEND $315,417 The Principal… $4,204,692
Texas A&M Engineering Experiment Station Y2 Amend ($6,557.50) Y2 Amend $90,000 Y1 Agree $90,000 We will generate acute gravitational dose-response curves of fluid shift, cardiovascular, and ocular… $173,443
Mainehealth Y1-$90,000, Y2 Long-duration spaceflight reduces bone quality via early onset osteoporosis. During spaceflight, the reduced gravitation loading on the… $180,000
The Johns Hopkins University Y4-AMEND ($36,479.71) Y4-AMEND $97,337 Y3-AMEND $41,606 Y3-AMEND $100,000 Y2-AMEND $99,612 Y1-AGREE $116,832 The original work plan for EXP0008 includes the… $418,907
Mainehealth Y1-AGRMT $90,000 Long-duration spaceflight reduces bone quality via early onset osteoporosis. During spaceflight, the reduced gravitation loading on the… $90,000
Wake Forest University Health Sciences Y1 Amend ($2,493) Y1 Agreement $50,547 The Human Research Program (HRP) aims to develop and provide knowledge, useful technologies, and countermeasures that… $48,054
University Of California, San Diego Y1 Agreement - $89,342 The objective of this project is to establish a rapid, simple and robust process for the production and purification of pharmaceuticals… $179,342
University Of Pittsburgh - Of The Commonwealth System Of Higher Education Y2 Amendment $90,000 Y1 Agreement - $90,000 My independent research will study the impact of global metabolic rate on musculoskeletal health, with the… $180,000
University Of California, Davis Y2 Amendment ($150,728.24) Y2 Amendment $124,880 Y1 Agreement $233,450 PI Jamison-Clung will lead the UC Davis team and oversee all project activities, with… $207,602
Trustees Of Tufts College Y2 AMEND ($210,399.32) Y2 AMEND $250,000 Y1-AGREE $250,000 The project leadership team will meet monthly across all eight quarters of the two-year funded period… $289,601
University Of Illinois Y2 Amend $500,000 Y1 AGREE $500,000 Astronauts in space are exposed to a wide variety of stressors, including microgravity, ultraviolet exposure, circadian… $1,000,000
University Of California, Davis Y1 AMEND ($168) Y1-AGREE $150,000 Our specific aim is to complete quantitative Figures of Merit (FOM) analyses (mass, volume, time, and power requirements)… $149,832
Texas A&M Engineering Experiment Station Y1 Amend $(47.84) Y1 AMEND $9,360 Y1 AMEND $27,900 Y1 AGREE $60,000 Dr. Artiles, in collaboration with the other senior personnel, will be responsible for the… $97,212
Rutgers, The State University Y2 Amend $47,097 Y1 Agreement $44,016 The proposed work will investigate the hypothesis that spaceflight stressors, including limited sources of vitamin B3,… $91,113
Board Of Regents Of Nevada System Of Higher Education Y2 Amend $105,840 Y1 AGREE $105,060 The aim of the project is to define the amount of the toxic ox-NAD(P) product formed following exposure to mimics of space… $210,900
University Of Alabama At Birmingham Y2 Amend $82,875 Y1 AGREE $79,905 The Gassman lab will conduct cell culture and molecular biology experiments to support the proposed work. The Migaud lab… $162,780
Regents Of The University Of Michigan Y3 Amend $(4,176.90) Y3 Amend $80,000 Y2 Amend $75,000 Y1 Agreement $75,000 INTRODUCTION: Space exploration exposes humans to unique stressors that if not… $225,823
University Of Hawaii Y1 Amend ($360.77) Y1 Amend $183,381 Y1 Agreement $150,000 For Aim 1, we will first compare and contrast three candidate smart phones and three smart watches… $333,020
The Trustees Of Columbia University In The City Of New York Y3 AMEND $750,000 Y2-Amend $750,000 Y1-Agree $750,000 Over the past decade, our laboratory has engineered a broad range of human tissues using induced… $2,250,000
University Of Florida Y2 DE-OB ($8,282) Y2 AMEND $80,000 Y1 AGREE $75,000 Investigating plantar somatosensory noise as a countermeasure for balance and locomotion impairments in… $143,846
Duke University Y3 AMENDM $749,999 Y2 Amend $749,999 Y1 Agree $750,000 Over the past decade, our laboratory has used engineered human vascular models starting from induced… $2,249,998
Starburst Accelerator, LLC Y1 Agree $100,000 Phase 1 – Program Framing, Planning & Project Management The goal of this phase is for the Starburst team to align with stakeholders on… $100,000
The Univeristy Of Texas M.d. Anderson Cancer Center Y2 Amend $90,000 Y1 Agree $90,000 Objectives: Our hypothesis for the proposed studies is that space radiation promotes a pro-inflammatory immune… $180,000
Wake Forest University Health Sciences Y2 AMEND-$420,514 At the completion of these studies, we will have: a) Established the modular MOE platform's utility as a much-needed in vitro system to… $420,514
Engineering Biology Research Consortium The Engineering Biology Research Consortium (EBRC) Team and key members will collaborate with select leadership from the Translational Research Institute for… $305,937
Level Ex Inc. Y2 AMEND $120,379 Level Ex will build upon the successful completion of the Virtual Human Simulation (VHS) project to create Fundamentals of Ultrasound -… $120,379
Texas State University Y1 AMEND $49,999 Y1 AGREE $400,005 The overall goal of the LBJ Institute's Space Health Inclusion Partnership (LBJ SHIP) is to assist TRISH in its effort to… $450,004
The Regents Of The University Of Colorado Y2 AMEND $90,000 Y1 AGREE $80,000 Here, we propose noisy Galvanic Vestibular Stimulation (nGVS) as a potential countermeasure to mitigate sensorimotor… $170,000
The Johns Hopkins University Y2 FINAL AMEND TOTAL $154,081.85 During the TRISH postdoctoral fellowship, Mallika Sarma will complete the following: • Expand expertise in two primary… $154,082
University Of Florida Y1 AMEND $40,640 Y1 AGREE $360,307 The investigators will achieve the following objectives, aimed at increasing diversity among space health researchers, per… $400,947
Massachusetts Institute Of Technology Y5 AMEND DE-OB ($2,639.81) Dr. Newman will pursue the institute’s goal is to recruit, inspire, and mentor trainees to become independent investigators.… $37,360
University Of Arkansas For Medical Sciences Y2 AMEND $90,000 Y1 AGREE $80,000 This project tests the hypothesis that two new ground-based mouse models of deep space travel will result in mitochondrial… $170,000
University Of Washington Y1 Agree - $500,000 Principal Investigator: Michael A. Williams, M.D. Overall Responsibilities: • Dr. Williams’ will oversee and coordinate the… $500,000
University Of South Alabama Y2 AMEND ($11,464) Y2 AMEND $208,364 Y1 AMEND (2,980) Y1 AGREE $245,784 Synthesis: 1.1 Sustained syntheses of (isotopic) ox-NAD(P) and (isotopic) PYR-TP 1.2… $439,703
Space Exploration Technologies Corp. Y4-Amend $285,725 Y3-Amend ($54,756) Y3-Amend $624,484 Y1-Amend ($76,150) Y2-Amend $433,599 Y1-Agree $450,000 The goals of this proposal have been developed… $1,662,902
University Of Hawaii Y2 AMEND FINAL DE-OB ($990.73) Y2 AMEND $75,000 Y1 AGREE $75,000 2- Years Research Plan Statement of Work (limited to 4000 characters) R/R&D work will be… $149,009
University Of Washington Y1 AGREE $500,000 Overall Responsibilities: • Dr. Williams’ will oversee and coordinate the efforts of all investigators • Work with Miethke,… $500,000
Blue Origin Texas, LLC Y2 AMEND $132,393 1. Conduct internal and external stakeholder assessments to identify obstacles to such research; 2. Identify a concept of operations and… $132,393
The Univeristy Of Texas M.d. Anderson Cancer Center Y3 AMEND $49,853 Y2 AMEND $155,504 Y1 AGREE $155,466 Project Title: Counteracting space radiation by targeting neurogenesis in a human brain organoid model… $360,823
The Univeristy Of Texas M.d. Anderson Cancer Center Y3 AMEND $96,789 Y2 AMEND $120,989 Y1 AGREE $119,983 Overview: Due to high numbers of stem cells and rapid turnover rate, the human small intestinal… $337,761
Wake Forest University Health Sciences Y4 amend $386,994 Y3 amend $386,222 Y2 amend $377,474 Y1 agree $262,679 $1,413,369
Colorado State University Y3 AMEND $184,737 Y2 AMEND $213,490 In year 1, we will install and commission a neutron irradiation/tissue culture facility consisting of a neutron generator… $213,490
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Quick answers

Who received award NNX16AO69A?

NNX16AO69A was awarded to Baylor College Of Medicine by Shared Services Center (National Aeronautics and Space Administration) on September 29, 2016.

How much is award NNX16AO69A worth?

$139,591,380 has been obligated on NNX16AO69A.

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