Exploration

Active

Assistance listing
43.003
Agency
Grant awards
593 $884,771,445 in federal obligations

Program facts

Also known as
Exploration Systems Development Mission Directorate (ESDMD)
Assistance types
  • Cooperative Agreement
  • Project Grant
Treasury account
  • 80-0124-0-1-252
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

NASA awards grants under the Exploration program (CFDA 43.003) to develop systems and capabilities for human exploration of the Moon and Mars, with the most recent award made on July 16, 2026. The program funds development of the Orion crew exploration vehicle, Space Launch System (SLS) rocket, Exploration Ground Systems (EGS), lunar orbit and surface infrastructure including the Gateway lunar station, Human Landing System (HLS), extravehicular activity systems, and habitation technologies for long-duration lunar and deep-space missions. Awards also support advanced cislunar navigation, surface mobility systems, and preliminary concept studies for eventual Mars transit habitats.

Activity has slowed significantly in recent years. The program issued 593 total awards since 2007, but the award cadence has dropped sharply—from 16 awards in both 2022 and 2023 to just 7 in 2024, 4 in 2025, and 2 through mid-2026. No recent grant opportunities are currently posted in the source material; the most recent opportunity documents date to late 2023 and earlier.

The portfolio comprises predominantly Project Grants (77 percent, 454 awards) with a substantial Cooperative Agreement share (23 percent, 139 awards). Combined federal dollars obligated total $884.8 million. NASA Shared Services Center dominates by both award count and funding magnitude, accounting for 428 awards and $510 million in federal obligations. NASA Goddard Space Flight Center ranks second by funding with just 3 awards but $256.1 million obligated, reflecting large infrastructure or research center awards. NASA headquarters accounts for 156 awards and $112 million; smaller contributions come from Stennis Space Center ($492 thousand across 3 awards) and Ames Research Center ($5.9 million, 1 award).

Recent awards illustrate the program's breadth. A $40,700 project grant (July 2026) funds design and construction of a Langmuir probe to characterize the polar lunar plasma environment. A $4.9 million Cooperative Agreement (August 2023) supports the Center for Lunar Environment and Volatile Exploration Research (CLEVER). Large infrastructure awards include a $76.1 million Cooperative Agreement to Goddard's Center for Research and Exploration in Space Science and Technology (October 2024) and a $54.9 million award for Human Systems Integration collaborative research (January 2022). Technology development spans additive manufacturing, lunar landing trajectory optimization, battery materials for low-temperature applications, and magnetic joint actuators for space applications.

The award profile reveals maturation of earlier development phases: mega-awards to established research centers have grown while new solicitations appear infrequent. The dramatic decline in annual award count suggests the program may be in a consolidation phase or awaiting new budget-cycle opportunities.

Objective and description

Objective

The Exploration Systems Development Mission Directorate (ESDMD) defines and manages systems development for programs critical to the NASA's Artemis campaign and planning for NASA's Moon to Mars exploration approach in an integrated manner. ESDMD mana

Description

Exploration provides for the development of systems and capabilities needed for human exploration of the Moon and Mars. ESDMD is building a space transportation system comprised of the Orion deep crew exploration vehicle, Space Launch System (SLS) rocket, and Exploration Ground Systems (EGS). These capabilities enable the Agency's Artemis missions, extending human presence into the solar system by transporting crews to lunar orbit and safely back to Earth in preparation for future missions to Mars. Advanced Cislunar and Surface Capabilities (ACSC), Gateway, Human Landing System (HLS), and Exploration Extravehicular Activity (xEVA) and Human Surface Mobility Program (EHP) will create the exploration infrastructure in lunar orbit and on the lunar surface that astronauts will utilize during Artemis missions and that will inform future missions to Mars. The Exploration Capabilities Program develops habitation systems and technologies to enable long missions on the lunar surface and in deep space and to address high priority technology gaps. MCD will begin conducting preliminary concept studies for future systems, including an eventual transit habitat that will provide living quarters and other basic life support functions for future human mission to Mars.

Eligibility

Applicant eligibility

Categories of organizations that may be eligible for NASA grants and cooperative agreements include: • Institutions of Higher Education (IHE) - A two- or four-year university or college (including U.S. community colleges), public or private, accredited to confer degrees beyond that of the K-12 grade levels. 29 • Educational Institutions - Non-higher-education entities, such as K-12 education groups or institutions of informal education, are classified as Educational Institutions.2 • Non-profit Organization - An organization that: o Is operated primarily for scientific, engineering, educational, research, or similar purposes in the public interest; o Is not organized primarily for profit; o Uses net proceeds to maintain, improve, or expand the organization's operations; and o Is not an IHE. Non-profit organizations generally exclude (i) colleges and universities; (ii) hospitals; and (iii) state, local, and Federally recognized Indian tribal governments. • For-profit Entity - An organization of any size that is organized primarily for profit. • Federally Funded Research and Development Center (FFRDC) - FFRDCs are under a broad charter by a Government agency for performing, analyzing, or conducting research for the United States Government. NASA sponsors JPL as the Agency's sole FFRDC, and JPL is not an eligible applicant to receive a NASA-funded grant or cooperative agreement as a recipient or subrecipient3 . However, FFRDCs sponsored by agencies other than NASA may be eligible to receive a NASA-funded award as a recipient or subrecipient. • Non-U.S. Organizations - Organizations outside the U.S. that meet the definitions of foreign organization or foreign public entity in 2 CFR § 200.1. Non-U.S. organizations generally propose for opportunities on a no-exchange-of-funds basis in accordance with NASA policy. NOFOs may be issued jointly with a non-U.S. organization (e.g., those concerning guest observing programs for jointly sponsored space science programs) that will contain additional special guidelines for non-U.S. participants. • State, Local, or Federally-Recognized Tribal Government Agency - o State Government means any state of the United States, the District of Columbia, the Commonwealth of Puerto Rico, any territory or possession of the United States, and any agency or instrumentality of a State exclusive of its local governments

Uses of assistance

Although NASA's statutory authority extends beyond research awards, the Agency primarily issues grants and cooperative agreements to support research and research-related activities. Such activities include, but are not limited to, education, travel, conferences, and training. Information on both active and closed NASA grants and cooperative agreements is publicly available at USAspending.gov. Applicants and recipients must refer to the applicable Notice of Funding Opportunity (NOFO) and award terms and conditions for program-specific requirements and additional details.

Use restrictions

Restrictions on the use of assistance for this listing are governed by the limitations and conditions set forth in NASA's Grant and Cooperative Agreement Manual (GCAM). The GCAM includes a dedicated section on limitations and restrictions, which outlines the circumstances under which funds may not be used. Applicants and recipients should refer to the applicable GCAM limitations provisions, in conjunction with the specific Notice of Funding Opportunity (NOFO), to understand any restrictions that apply. Only restrictions that are unique to this Assistance Listing or organization are identified here; all other standard limitations apply as described in the GCAM.

Length and time phasing of assistance

Generally, up to three years but no more than five years. Review funding opportunity announcement for additional information.

How to apply

Preapplication coordination

This program is excluded from coverage under E.O. 12372. Applicants must follow the proposal submission instructions outlined in the applicable Notice of Funding Opportunity (NOFO). Specific submission requirements-including whether a Notice of Intent (NOI) and/or Phase I proposals are required-are defined in the individual funding opportunity announcement and may vary by program. In addition, all Principal Investigators (PIs) and Co-Investigators (Co-Is) must register in NASA's Solicitation and Proposal Integration and Review System (NSPIRES) at https://nspires.nasaprs.com/external as NSPIRES is used to support proposal submission, review, and award processing.

Criteria for selecting proposals

All proposals will undergo an administrative, merit, and financial review. The NASA funding organization responsible for managing the technical aspects of an awarded effort is responsible for the merit review process, which may be based on peer review. All applications for NASA discretionary awards are subject to a merit review with the objective of selecting the recipient most likely to be successful in delivering results based on the objectives outlined in this Assistance Listing. Applicants may consult the NASA Grant and Cooperative Agreement manual for additional information on NASA Proposal review and selection process. https://www.nasa.gov/grants-policy-and-compliance-team/#Regulations

Award procedure

After proposals are submitted, NASA evaluates all applications to determine funding selections, and applicants are notified of the outcome by email. Award selection announcements generally occur 150 to 220 days after the proposal due date, following approval of NASA funding through the federal budget process. Selection timelines may be extended due to budget delays, required final approvals and concurrence, or if additional information is needed from the applicant, such as revised budgets or supporting details required to finalize the award.

Deadlines

Applicants should review funding opportunity announcement for specific deadlines and other key dates.

Time to approval or disapproval

For information on application review procedures, applicants should refer to the applicable section of Proposal Review and Selection Criteria of the GCAM: https://www.nasa.gov/grants-policy-and-compliance-team/#Regulations

Renewals

Renewal and extension information can be found in the NASA Grants and Cooperative Agreement Manual (GCAM) and the NASA NSSC website at https://www.nasa.gov/centers/nssc/grants

Appeals

Information on NASA appeals policy and process can be found in the NASA Grant and Cooperative Agreement Manual (GCAM), and does not apply to proposals returned without review by NASA for an applicant's failure to: a. Submit a late proposal where information regarding the proposal deadline (i.e., date, time, and location) for submission had been previously specified. b. Meet the NASA proposal preparation requirements, such as page limitations, formatting, instructions, and electronic submission. c. Submit a proposal that is responsive to the NOFO or that contains sufficient detail. d. Submit the proposal with enough lead time before the activity is to commence.

Grant opportunities

Opportunity Status Posted Applications due
2023 Human Exploration Research Opportunities (HERO) Overview NNJ23ZSA001N Closed
2023 HERO Appendix A: NASA Human Research Program Omnibus Opportunity NNJ23ZSA001N-OMNIBUS Closed
2021 HERO Appendix A: Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions NNJ21ZSA001N-FLAGSHIP Closed
2021 Human Exploration Research Opportunities (HERO) NNJ21ZSA001N Closed
2021 HERO Appendix B: NASA Human Research Program Omnibus Opportunity NNJ21ZSA001N-OMNIBUS Closed
2020 HERO Appendix F: NASA Human Research Program Omnibus Opportunity 80JSC020N0001-OMNIBUS3 Closed
2020 HERO Appendix E: Human Health and Performance Topics 80JSC020N0001-HHP Closed
2020 HERO Appendix C: Human Health Countermeasures and Space Radiation Topics 80JSC020N0001-HHCSR Closed
2020 HERO Appendix D: NASA Human Research Program Omnibus Opportunity 80JSC020N0001-OMNIBUS2 Closed
2020 HERO Appendix A: NASA Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions 80JSC020N0001-FLAGSHIP Closed
2020 HERO Appendix B: NASA Human Research Program Omnibus Opportunity 80JSC020N0001-OMNIBUS1 Closed
2020 Human Exploration Research Opportunities (HERO) 80JSC020N0001 Closed
HERO Appendix G: Team Composition 80JSC019N0001-TEAM Closed
HERO Appendix E: Topics in Human Factors and Behavioral Performance 80JSC019N0001-HFBP Closed
HERO Appendix F: NASA Human Research Program Omnibus Opportunity 80JSC019N0001-OMNIBUS3 Closed
Dual Use Technology Development Cooperative Agreement Notice (CAN) 2020 80SSC020Z0001 Closed
HERO Appendix C: Topics in Human Health Countermeasures, Behavioral Performance, and Space Radiation 80JSC019N0001-HHCBPSR Closed
HERO Appendix D: NASA Human Research Program Omnibus Opportunity 80JSC019N0001-OMNIBUS2 Closed
ROSBio Appendix D: Solicitation of Proposals for Flight and Ground Space Biology Research NNH18ZTT001N-FG2 Closed
Use of the NASA Physical Sciences Informatics System - Appendix F NNH17ZTT001N-17PSI-F Closed
HERO Appendix A: NASA Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions 80JSC019N0001-FLAGSHIP Closed
Human Exploration Research Opportunities (HERO) 80JSC019N0001 Closed
HERO Appendix B: NASA Human Research Program Omnibus Opportunity 80JSC019N0001-OMNIBUS Closed
Appendix D: Topics in Human Health Countermeasures, Human Factors, and Behavioral Performance 80JSC018N0001-HHCHFBP Closed
Appendix B: Solicitation of Proposals for Flight and Ground Space Biology Research NNH18ZTT001N-FG Closed
Appendix C: Countermeasures for Mitigation of Spaceflight Associated Neuro-ocular Syndrome 80JSC018N0001-SANS Closed
Use of the NASA Physical Sciences Informatics System - Appendix E NNH17ZTT001N-17PSI-E Closed
2018 Human Exploration Research Opportunities (HERO) 80JSC018N0001 Closed
Appendix A: NASA Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions 80JSC018N0001-FLAGSHIP Closed
Appendix B: NASA Human Research Program Omnibus Opportunity 80JSC018N0001-OMNIBUS Closed
ROSBio Appendix A: Orion Exploration Mission-1 Research Pathfinder for Beyond Low Earth Orbit Space Biology Investigations NNH18ZTT001N-EM1 Closed
Dual Use Technology Development Cooperative Agreement Notice (CAN) 2018 80SSC017Z0001 Closed
Appendix C: Topics in Biological, Physiological, and Behavioral Adaptations to Spaceflight: Integrated One Year Mission Project and Other Opportunities 80JSC017N0001-BPBA Closed
ROSBio Appendix G: Solicitation of Proposals for Flight and Ground Space Biology Research NNH16ZTT001N-FG Closed
Use of the NASA Physical Sciences Informatics System - Appendix D NNH17ZTT001N-17PSI-D Closed
ROSBio Appendix F: Solicitation of Proposals to Conduct Research on Antarctic Balloon Flights NNH16ZTT001N-AB Closed
ROSBio Appendix D: Solicitation of Proposals to Conduct Research Using Microgravity Simulation Devices NNH16ZTT001N-MS Closed
ROSBio Appendix E: Solicitation of Proposals to Conduct Research In Parabolic and Suborbital Flights NNH16ZTT001N-PS Closed
Appendix A: NASA Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions 80JSC017N0001-FLAGSHIP1 Closed
Appendix B: NASA Human Research Program Omnibus Opportunity 80JSC017N0001-OMNIBUS Closed
ROSBio Appendix C: Solicitation of Proposals for Possible Inclusion in a Russian Bion-M2 Mission NNH16ZTT001N-BION Closed
2017 Human Exploration Research Opportunities (HERO) 80JSC017N0001 Closed
HERO Appendix E: Space Radiobiology and Human Health Countermeasures Topics NNJ16ZSA001N-SRHHC — —
Dual Use Technology Development at NASA John C. Stennis Space Center NNS17ZDA001C Closed
Use of the NASA Physical Sciences Informatics System - Appendix B NNH15ZTT001N-15PSI-B Closed
Research Opportunities in Materials Science - MaterialsLab Open Science Campaigns for Experiments on the International Space Station NNH15ZTT002N Closed
Human exploration research opportunities NASA research announcement NNJ15ZSA001N Closed
Use of the NASA Physical Sciences Informatics System - Appendix A NNH15ZTT001N-15PSI-A Closed
Technology advancing partnerships call at john f. Kennedy space center NNK15AD01A Closed
Spaceflight Research Opportunities in Space Biology NNH14ZTT001N Closed
Show 40 more

Latest 50 listed here. See the rest on GovTribe.

Grant awards

Award Recipient Federal obligations Awarded
The polar lunar plasma environment is poorly known and characterizing IT is of paramount importance for human space… 80NSSC26K1135 Embry-Riddle Aeronautical University, Inc. $40,700
Support for the 2026 space generation congress (SGC) the 2026 space generation fusion forum and SGX 2026 conferences… 80NSSC26K0641 Space Generation Advisory Council $46,500
The dual use technology development program s objective is to create partnerships with U.S. Industry and… 80NSSC25M7059 The University Of Texas At El Paso $64,358
The dual use technology development program s objective is to create partnerships with U.S. Industry and… 80NSSC25M7053 University Of Tennessee $45,267
This opportunity seeks to build knowledge and technologies required to traverse and navigate the complex cislunar… 80NSSC25M7050 Purdue University $85,000
Execute a balanced science program based on discipline-specific guidance from the national academies of sciences… 80NSSC25M7031 The Ohio State University $144,624
The dual use technology development program s objective is to create partnerships with U.S. Industry and… 80NSSC25M7058 Auburn University $85,911
The goddard center for research and exploration in space science and technology (cresstii) will carry out observational… 80GSFC24M0006 University Of Maryland, College Park $76,110,879
CAN24-123 filler metal for repair of high strength aluminum components 80NSSC24M0203 Fortius Metals, Inc. $1
Single source timeline verification statement of work 80NSSC24M0199 Iowa State University Of Science And Technology $174,606

Latest 10 of 593 listed here. See the rest on GovTribe.

Top recipients by federal obligations

Rank Recipient Federal obligations Share
1 University Of Maryland, College Park $256,145,864 29%
2 Baylor College Of Medicine $141,261,185 16%
3 San Jose State University Research Foundation $65,106,284 7%
4 The University Of Texas Southwestern Medical Center $22,932,704 3%
5 Georgetown University $20,015,668 2%
6 Colorado State University $16,357,783 2%
7 The Regents Of The University Of Colorado $14,260,498 2%
8 Duke University $12,920,956 1%
9 The Trustees Of The University Of Pennsylvania $11,312,877 1%
10 University Of California Irvine $11,104,872 1%

10 of 226 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $45,992,684
FY2025 $86,688,896
FY2024 $65,484,063
FY2023 $77,403,970
FY2022 $61,951,417
FY2021 $62,880,722
FY2020 $65,683,389
FY2019 $89,428,882
FY2018 $58,793,442
FY2017 $39,565,503
FY2016 $29,334,972
FY2015 $28,684,118
FY2014 $27,262,612
FY2013 $22,989,930
FY2012 $19,206,974
FY2011 $19,097,491
Show all 16

Quick answers

What is Assistance Listing 43.003?

Assistance Listing 43.003 is Exploration, a federal grant program run by National Aeronautics and Space Administration.

What is the CFDA number for Exploration?

Its CFDA number is 43.003: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 43.003 awarded?

593 grant awards under 43.003 have obligated $884,771,445 in federal funds to 226 recipients.

Who receives the most funding from 43.003?

The recipients obligated the most under Exploration are University Of Maryland, College Park ($256,145,864), Baylor College Of Medicine ($141,261,185) and San Jose State University Research Foundation ($65,106,284).

How much did 43.003 obligate in fiscal year 2025?

Grants under 43.003 obligated $86,688,896 in federal funds in fiscal year 2025.

Are there open grant opportunities under 43.003?

None of the latest 50 opportunities under 43.003 is open now. The latest, 2023 Human Exploration Research Opportunities (HERO) Overview, was posted on December 1, 2022.

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