Cooperative Agreement 23OTASD0006

This Project Grant award for $650,000 was provided by the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program. The grant supports the development of a novel mucosal vaccine approach to control bovine tuberculosis (BTB) caused by Mycobacterium tuberculosis variant bovis (M. bovis) in livestock and wildlife populations. The principal investigator at the University of Missouri System will engineer immunogenic proteins from the M. tuberculosis complex into...

Montana State University was awarded a $644,000 Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The three-year grant will fund research to better understand Mycoplasma ovipneumoniae, a bacterium that infects domestic sheep and can lead to asymptomatic colonization in adult sheep or severe pneumonia outbreaks in lambs and wild ruminants. Specifically, the...

Montana State University received a three-year, $176,186 Project Grant award from the United States Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The grant will fund research into Mycoplasma ovipneumoniae, a bacterial pathogen of sheep that can cause respiratory disease, especially when co-occurring with other pathogens such as Mannheimia haemolytica. The university researchers will...

The Department of Agriculture's National Institute of Food and Agriculture awarded Kansas State University $650,000 under the Agriculture and Food Research Initiative competitive grants program to develop improved vaccines for bovine respiratory disease complex. With funding through May 2026, the university aims to generate new knowledge needed to design vaccines capable of protecting calves against multiple strains of Bovine parainfluenza virus 3 and Bovine viral diarrhea virus. Researchers...

Long Island University received a three-year, $627,000 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The grant will fund research to develop an improved vaccine for bovine respiratory disease (BRD) in cattle. BRD costs the U.S. beef industry over $3 billion annually. Current commercial vaccines have limited effectiveness. The university will generate...

The U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) awarded a $225,000 Agriculture and Food Research Initiative (AFRI) project grant to the Division of Agriculture of the University of Arkansas. The grant will fund a 2-year research project to characterize the probiotic capabilities of commensal Corynebacterium bacteria isolated from the bovine respiratory microbiota. The goal is to evaluate the potential of these bacterial isolates to inhibit the growth...

This $150,000 cooperative agreement from the United States Department of Agriculture Agricultural Research Service will fund research at the Universidad Autónoma De Querétaro in Mexico to understand and control bovine babesiosis. Over five years, the university will 1) compare genome sequences to understand genetic variation in pathogens that cause bovine babesiosis, 2) determine infection rates in cattle using molecular and serological assays, and 3) provide risk assessment for the spread of...

The U.S. Department of Agriculture (USDA) awarded a $650,000 project grant to Oklahoma State University (OSU) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The grant aims to identify cellular and viral genes that induce reactivation of Bovine Herpesvirus 1 (BoHV-1) from latency in cattle. Understanding the mechanisms of BoHV-1 reactivation will allow the development of improved vaccine strategies to reduce the spread of the virus and incidence of Bovine...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $447,009 to the University of Massachusetts to conduct research on the early immune response to Mycobacterium tuberculosis (MTB) infection. The key objectives are to: 1) Categorize alveolar macrophage sensing abilities and defects in responding to MTB pathogen-associated molecular patterns, and screen for novel...

This Project Grant award of $800,000 from the U.S. Department of Agriculture's Agriculture and Food Research Initiative (CFDA 10.310) supports two critical solutions to address the emerging threat of Influenza D virus (IDV) in cattle: Development of new diagnostic tests to monitor IDV in cattle and other livestock, led by the University of Pittsburgh in collaboration with South Dakota State University. Development of an innovative nasal spray vaccine to protect cattle from IDV and prevent the...