Purchase Order 75N98026P00480
- Not listed
- The National Institutes of Health's National Center for Advancing Translational Sciences awarded a $99,000 firm fixed price purchase order to Targetmol Chemicals Inc. to synthesize analogs of repsox and intermediates from two ongoing medicinal chemistry projects. Over a six-month period after receipt of order, Targetmol will synthesize the requested compounds and deliver milligram to gram quantities to NCATS along with electronic progress reports, analytical data including LCMS and 1H NMR, and...
- The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) awarded a $30,035 firm fixed price purchase order to Medchemexpress LLC of Princeton, New Jersey for the synthesis of synthetic compounds to support NCATS. Under the terms of the award, Medchemexpress will provide synthetic compound synthesis services to NCATS by November 11, 2022. No set-aside provisions were applied to this procurement. As the lead institute for NIH's translational...
- The National Center for Advancing Translational Sciences (NCATS), a division of the National Institutes of Health, awarded a $59.8K firm fixed-price purchase order to Reaction Biology Corporation for bioactive small molecule development services. The contract, awarded on September 19, 2025, with an ultimate completion date of September 22, 2026, encompasses Gamma 33P ATP kinase assay and NanoBRET kinase assay services to be performed at the contractor's facility in Malvern, Pennsylvania. This...
- The National Center for Advancing Translational Sciences (NCATS) awarded a $24,150 firm fixed-price purchase order to Davos Chemical Corp. to procure analytical characterization services for a small molecule pyruvate kinase activator compound (NCGC-4932). The scope of work involves defining and characterizing the solid-state properties of the free base form of this pharmaceutical agent. This contract represents a targeted procurement supporting NCATS's mission to accelerate the translational...
- The National Institute on Drug Abuse awarded a $101,000 firm fixed-price purchase order to Chemogenics Biopharma, LLC on September 16, 2025, for synthesis and bioanalytical analysis services supporting the National Center for Advancing Translational Sciences (NCATS) Early Translational Branch Chemistry Program. The contract, which extends through July 15, 2026, is performable in Durham, North Carolina. This procurement does not utilize a small business set-aside designation. The work involves...
- This $29,376 firm-fixed-price purchase order was awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH), to Reaction Biology Corporation, a self-certified small disadvantaged business. The award is to obtain kinase hotspot assay compound testing services from Reaction Biology. This contract is not associated with a larger vehicle. The purpose is to test 120 novel small molecule compounds for inhibitory activity...
- The National Cancer Institute awarded a $42,941.42 delivery order to Alchem Laboratories Corporation for the non-Good Manufacturing Practice (non-GMP) synthesis of 100 grams of (R)-N-(6-chloro-4-((1-phenylethyl)amino)pyrido[3,4-d]pyrimidin-5-yl)methanesulfonamide (MTX-531), a small molecule compound. The contract was awarded on July 22, 2022, with an ultimate completion date of October 21, 2022, under a cost-plus-fixed-fee pricing structure. This award was designated as a Total Small Business...
- This is a firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH), to Cellmosaic, Inc., a small disadvantaged business, for the synthesis and delivery of 100g of the lead NNMT inhibitor compound '960 over a 12-month period. The total contract value is $45,000.00. The award was made through a non-competitive, commercial item acquisition under FAR Parts 13 and 12, as Cellmosaic was...
- This is a $447,635.80 firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency within the U.S. government. The contract is for the "SMALL MOLECULES FOR NCATS PHARMACOLOGICALLY ACTIVE CHEMICAL TOOLBOX (NPACT)" program and was awarded to Analyticon Discovery, LLC, a for-profit foreign-owned organization. The contract does not have a set-aside designation and has an ultimate completion date of January 31, 2016. NCATS is...
- This $16,035 firm-fixed price purchase order was awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the U.S. Department of Health and Human Services, to MedChemExpress LLC, a New Jersey-based foreign-owned minority-owned small business. The award is for the acquisition of 2 grams of Minnelide (CAS: 1254702-87-8) and 10 grams of GNE-618 (CAS: 1362151-42-5), which are chemical compounds used to support NCATS' biomedical research programs. MedChemExpress has...
The National Center for Advancing Translational Sciences (NCATS) awarded a purchase order to Karebay Biochem Inc. for $38,600 on May 11, 2026, to provide calibration services for analytical instruments. Work is performed in Rockville, Maryland. The order covers synthesis of two specialized JAK2 inhibitor compounds at 95% purity, confirmed by NMR and LCMS analysis, for brain cancer cell assays: 10 grams of 4-amino-N,N-dicyclopropyl-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide and 2.5 grams of N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide. The contractor must deliver within two months of order approval. This procurement originated from Special Notice 75N98026Q00251, a sole-source acquisition under FAR 6.302-1 and conducted under FAR Part 12 and Part 13 simplified procedures. Ultimate completion is May 10, 2027.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
NOI- Preparation of chemical compounds needed for a Janus kinase 2 (JAK2) enzyme project | 75N98026Q00251 | Department of Health and Human Services National Institutes of Health Office of Logisitics and Acquisition Operations | Special Notice 1/1 | 4/23/26, 1:29 PM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $38.6k | 5/10/26 |