Proteome-wide cellular thermal shift assay (CETSA) analysis of RR-hydroxynorketamine (RR-HNK). This requisition is for melt and shift curves over 4000 protiens to deconvolute the target of RR-HNK.
Active Purchase Order Awarded Last action
- Contract number
- 140D0425P0202
- Awardee
-
Pelago Bioscience AB UEI PXCTD3HCRKN4
- Awarding agency
-
Interior Business Center
Office of Policy Management and Budget, Department of the Interior
- Obligated
- $30,400
Award facts
- Opportunity
-
- Notice of Intent to Sole Source Special Notice · 140D0425Q0740 · Posted Aug 19, 2025
- Contract value 100% obligated
- $30,400.00 Current and potential, with all options
- Completion date 74% complete
- Current and potential, with all options
- Funding agency
- National Center for Advancing Translational Sciences National Institutes of Health, Department of Health and Human Services
- NAICS code
- 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- PSC
- AJ11 General Science And Technology R&D Services; General Science And Technology; Basic Research
- Set-aside
- No set-aside
- Competition
- Not Competed under SAP · 1 offer Simplified Acquisition
- Pricing
- Firm Fixed Price
- Place of performance
- Sweden
- Legislative mandates
-
- Other statutory authority
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Supplemental Agreement for work within scope | $0 | |
| Supplemental Agreement for work within scope | $0 | |
| Original award | $30,400 |
About this award
The National Center for Advancing Translational Sciences awarded a purchase order to Pelago Bioscience AB on September 23, 2025, for $30,400 in proteome-wide Cellular Thermal Shift Assay analysis of RR-hydroxynorketamine. Work is performed in Sweden. The order calls for melt and shift curves across 4,000 proteins to deconvolute the molecular target of RR-HNK, supporting NCATS' development of new bioactive small molecules for multiple disease indications. The contract was sole-sourced under FAR 13.106-1(b)(1) to ensure data consistency and comparable sample analysis, building on the contractor's prior work on this project. Performance concludes March 31, 2027.
Quick answers
Who was awarded contract 140D0425P0202?
140D0425P0202 was awarded to Pelago Bioscience AB by Interior Business Center (Office of Policy Management and Budget) on September 23, 2025.
How much is contract 140D0425P0202 worth?
The government has obligated $30,400 on 140D0425P0202.
Which agency awarded contract 140D0425P0202?
Interior Business Center (Office of Policy Management and Budget) awarded 140D0425P0202, with funding from National Center for Advancing Translational Sciences (National Institutes of Health).
Was contract 140D0425P0202 competed?
The extent of competition for 140D0425P0202 was not competed under sap. The government received 1 offer.
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