Exploration technology demonstration and national lab utilization enhancements bioserve support services for the micro 12 payload this study intends to systematically investigate the effects of…

This is a firm fixed-price delivery order contract awarded by the National Aeronautics and Space Administration (NASA) Johnson Space Center to The Regents of the University of Colorado, for the Micro 12 payload on the International Space Station. The contract, valued at $322,821.00, is for the University to provide turn-key mission integration and operation services, including space flight hardware like the Cell Growth Biopharmaceutical Apparatus (CGBA) or Slow Accelerated Growth Apparatus (SABL) incubator, to support research investigating the effects of microgravity on an exoelectrogenic microorganism, Shewanella oneidensis MR-1. This research directly addresses recommendations from the Decadal Survey report on cell, microbial, and molecular biology in space. The contract has no set-aside designation.

Exploration technology demonstration and national lab utilization enhancements bioserve support services for the micro 12 payload this study intends to systematically investigate the effects of spaceflight and microgravity on the physiology of a model exoelectrogen, shewanella oneidensis MR 1, using a combination of genetic, biochemical, and, omic, approaches. No space research has been conducted in this area and IT is unclear whether biofilm changes will have an impact, negative or positive, on bioelectrochemical systems, BES, technology. This flight experiment directly address decadal survey report recommendations P2, establish a robust space flight program of research analyzing plant and microbial growth and physiological responses to the multiple stimuli encountered in space flight environments, and will directly address the following overarching questions for cell, microbial, and molecular biology, CMM, in the space biology science plan, i.e., CCM 1, how do alterations in gravity affect: 1. Cell and microbial replication including genetic and metabolic regulation? And 2. Microbial biofilm formation and/or altered potential for disease?, and CMM 5, what are the genetic changes underlying physiological responses to space flight demonstrated in biological systems. Bioserve will provide its full service turn-key mission integration and operation services and associated space flight hardware which includes 36 gaps and 288 fpas, flight and ground, and its sabl or cgba incubator on board ISS, to support the slps micro 12 payload entitled, investigating the physiology and fitness of an exoelectrogenic microorganism under microgravity conditions. This scope of work includes: providing or coordinating the use of all space flight hardware required to meet the micro 12 experiment objectives. This includes cgba or sabl on board ISS for incubation, 36 gaps and 288 fpas, flight and ground combined. Coordinating the usage of cold stowage assets for transport to or from ISS: 4C on ascent and 4C and 95C on descent. Completing all necessary tasks to launch and operate the micro 12 experiment on the appropriate targeted mission, spacex 12 targeted mission. Specifically, bioserve will manage and perform all of the work necessary for the successful integration, launch, on orbit operations, and return of samples for the micro-12 experiment.