Hydrogel Embedded Dexamethasone for the Traumatic Brain Injury (TBI)
This Special Notice from the Walter Reed Army Institute of Research (WRAIR) seeks capability statements for providing Hydrogel Embedded Dexamethasone support for traumatic brain injury research. Respondents are requested to describe experience conducting studies to evaluate the pharmacokinetic profile and therapeutic efficacy of dexamethasone-embedded hydrogels in attenuating injury-induced edema, neuroinflammation, and behavioral dysfunction when administered post-injury.
The purpose of this Special Notice is to gather information to analyze small business capacity for a potential future set-aside to provide Hydrogel Embedded Dexamethasone for the Traumatic Brain Injury research program. Responses are due by June 3, 2020 and limited to five pages. Interested parties should demonstrate experience monitoring research animals, analyzing data, preparing reports and samples, and collaborating with WRAIR researchers on traumatic brain injury studies. Eligible respondents will assist in furthering the government's understanding of using dexamethasone-embedded hydrogels to treat traumatic brain injury.
W81XWH20R0066 Department of the Army Medical Command
5/27/20, 4:25 PM Rat Biomarker Analysis Services
This is a notice of intent to issue an award on the basis of other than full and open competition in accordance with the Federal Acquisition Regulation (FAR) 6.302-1 only one responsible source and no other supplies of services will satisfy agency requirements.
The US Army Medical Research Acquisition Activity (USAMRAA) intends to issue a single source award to the Quanterix Corporation. The total award amount is estimated to be $86,000.00.
Objectives: The objective of this requirement is to provide high-quality biomarker analytical services of rat blood samples for biochemical markers of neuronal, glial, and axonal damage (NF-L, tau, GFAP and UCH-L1) Samples will be provided by USARIEM.
Specific Tasks/Requirements:
1. The Contractor shall provide Accelerator Consumables Kit – all materials required to run three 96-well plates, including discs, tips, cuvettes, buffers, and sealing oil.
2. The Contractor shall provide Neurology 4-Plex A Kit (containing NF-L, tau, GFAP, and UCH-L1) – for running three 96-well plates of a Simoa 4-plex assay.
3. The Contractor shall provide Data analysis service charge – includes running of three plates in the Simoa Accelerator, data analysis, report, quality control procedures, and data review.
4. Contractor shall be available to answer and respond within 24 hours to USARIEM questions regarding sample analysis.
5. Disposal of unused sample volumes and return of Government shipping containers. Unless otherwise directed by the COR, the contractor shall dispose of any unused sample volumes no earlier than 60 days from the date of acceptance of analytical results by the Government. Disposal shall be done in accordance with all applicable laws and regulations required by the contractor’s facility.
6. All Government shipping containers, unless otherwise specified, shall be returned to the COR within three days of receipt if needed.
Period of Performance: A base of one year, plus 4 option years: 12/20/2019 through 12/19/2024
This is not a formal solicitation or request for quote. This synopsis of intent is to give notice of the Government's intent to make a sole source award. Contractors who can provide USAMRAA with the required services are invited to electronically submit an affirmative, written response indicating a bona fide ability to meet this specific requirement. Responses should appear on company letterhead and include, at minimum, affirmation of active registration in the System for Award Management (SAM), your Data Universal qualifications, and any applicable pricing data or information. All responses should include a point of contact, telephone number, and electronic mail address. Additionally, respondents should indicate whether they are a large business, small business, small disadvantaged business, 8(a) concern, women-owned small business, HUBZone, service disabled veteran-owned small business, or qualify as socially or economically disadvantaged and whether they are U.S. or foreign owned. Responses to this notice will be used to determine the availability of this type of service. All responsible sources may respond to this synopsis and all responses will be considered by the agency.
Responses should be furnished electronically to Ashley Atkins via email at: Ashley.n.atkins.civ@mail.mil no later than 08:00AM Eastern Standard Time, 03 December 2019.
W81XWH20Q0011 Department of the Army Medical Command
11/19/19, 10:40 AM Natural history studies of rubella-associated granulomatous lesions in aged individuals
The Centers for Disease Control and Prevention intends to award a sole source fixed-price purchase order to The Medical College of Wisconsin, Inc., for the procurement of a natural history study of rubella-associated granulomatous lesions in aged individuals.
This project will estimate the prevalence of rubella virus (RV)-associated granulomas in normal, aged individuals with cutaneous granulomas and assess the frequency and intensity of virus shedding by these long-term RV carriers. These results will help ascertain the impact of long-term RV carriers on CDC’s programmatic activities aimed on maintenance of rubella elimination in the United States. The Contractor will perform retrospective medical chart reviews to determine the numbers of patients with cutaneous granulomas at their institution during 2010–2020 and collect specimens (archival tissues blocks, prospective nasopharyngeal swabs) to determine the proportion of RV-associated granulomas and likelihood of virus shedding.
The Medical College of Wisconsin, Inc., has a computerized database of granuloma cases spanning the past 10 years and maintains a unique collection of archival skin biopsy specimens collected during last 10 years. We have not identified any other organization that has the expertise or collection of archival skin tissues necessary to meet this requirement.
This contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 13.106-1(b) (SAP) and 41 U.S.C. 3304(a)(1). Interested persons may identify their interest and capability to respond to the requirement or submit proposals.
This notice of intent is not a request for competitive quotations; however, all quotations/responses received within seven (7) days of the issuance of this notice will be considered by the government. A determination by the government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to the Contract Specialist at JHouston2@cdc.gov by 5:00PM Eastern Standard Time on Wednesday, February 19, 2019.
42153 Department of Health and Human Services Centers for Disease Control and Prevention Office of Acquisition Services
2/12/20, 3:28 PM Genotyping Onion DNA
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. Solicitation number 12505B20R1012731 is issued as a request for proposal (RFP). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2020-08. This solicitation will be a 100% Total Small Business Set-Aside. The associated NAICS code is 541714 (Research and Development in Biotechnology), with a small business size standard of 1,000 employees.
This acquisition is for the following item as identified in the Contract Line Item Number (CLIN):
0001) Genotyping of 192 Onion DNA
Specifications: See attached Statement of Work.
The Contractor shall provide all items F.O.B. destination. Location of the Government site is aboard USDA ARS Madison, WI 53706 and will be identified in the contract. The Government anticipates award of a Firm Fixed Price contract.
Offerors responding to this announcement shall submit their proposal in accordance with FAR 52.212-1. Submission of proposal shall include the following: (1) Technical Specifications and (2) Price (to include shipping).
All responses shall be submitted electronically to josh.dobereiner@usda.gov.
The basis for award is Best Value to the Government. "LPTA" means the best value is expected to result from selection of the technically acceptable proposal with the lowest evaluated price. Pursuant to FAR 52.212-2, the criteria for evaluation are: (1) Technical Specifications and (2) Price (to include shipping) and must also have satisfactory Past Performance. The lowest priced proposal will first be evaluated for technical acceptability in accordance with the minimum specifications identified. If determined not technically acceptable, it will be removed from competition and the next lowest priced proposal will be evaluated for technical acceptability. This will continue until the lowest price proposal is determined technically acceptable. Once the lowest priced proposal is determined technically acceptable, then a determination of responsibility will be completed. If found responsible, evaluations will be closed and award will be made.
INSPECTON AND ACCEPTANCE TERMS: Supplies will be inspected by Contracting Officer Representative (COR) and accepted at destination. Delivery is requested by December 1, 2020.
The following Federal Acquisition Regulation (FAR) and the Department of Agriculture Acquisition Regulation (AGAR) provisions and clauses apply to this acquisition: FAR 52.203-19 Prohibition on Requiring Certain Internal Confidentiality Agreements or Statements; FAR 52.204-7 System for Award Management; FAR 52.204-16 Commercial and Government Entity Code Reporting; FAR 52.204-17 Ownership or Control of Offeror; FAR 52.204-18 Commercial and Government Entity Code Reporting; FAR 52.204-23 Prohibition on Contracting for Hardware, Software, and Services Developed or Provided by Kaspersky Lab and Other Covered Entities; FAR 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment; FAR 52.204-25 Prohibition on Contracting for Certain Telecommunications and Video Surveillance Services or Equipment; AGAR 452.204-70 Inquiries; FAR 52.209-10 Prohibition on Contracting with Inverted Domestic Corporations; AGAR 452.209-71 Assurance Regarding Felony Conviction or Tax Delinquent Status for Corporate Applicants; FAR 52.212-1 Instructions to Offers-Commercial Items; FAR 52.212-2 Evaluation-Commercial Items (filled in as follows: Technical specifications and price); FAR 52.212-3 Offeror Representations and Certifications—Commercial Items; FAR 52.212-4 Contract Terms and Conditions-Commercial Items; FAR 52.212-5 Contract Terms and Conditions Required to Implement Statutes of Executive Orders-Commercial Items; FAR 52.219-6 Notice of Total Small Business Set-Aside; FAR 52.219-14 Limitations on Subcontracting; FAR 52.219-28 Post Award Small Business Program Rerepresentation; AGAR 452.219-70 Size Standard and NAICS Code Information; FAR 52.222-21 Prohibition of Segregated Facilities; FAR 52.222-26, Equal Opportunity; FAR 52.222-41 Service Contract Labor Standards; FAR 52.222-42 Statement of Equivalent Rates for Federal Hires; FAR 52.222-50 Combating Trafficking in Persons; FAR 52.222-55 Minimum Wages Under Executive Order 13658; FAR 52.222-62 Paid Sick Leave Under Executive Order 13706; FAR 52.223-18 Encouraging Contractor Policy to Ban Text Messaging While Driving; FAR 52.225-13 Restrictions on Certain Foreign Purchases; FAR 52.225-25 Prohibitions on Contracting with Entities Engaging in Certain Activities or Transactions Relating to Iran—Reps and Certs; FAR 52.232-33 Payment by Electronic Funds Transfer-System for Award Management; FAR 52.232-40 Providing Accelerated Payments to Small Business Subcontractors; FAR 52.233-3 Protest After Award; FAR 52.233-4 Applicable Law for Breach of Contract; FAR 52.252-1 Solicitations Provisions Incorporated by Reference; FAR 52.252-2 Clauses Incorporated by Reference.
To be eligible for an award, all contractors must be registered in the System for Award Management (SAM). A contractor can contact SAM by calling 1-866-606-8220 or e-mail at www.sam.gov. NO EXCEPTIONS. A DUNS (Dun and Bradstreet) number is required in order to register. All invoices shall be submitted electronically.
Proposals are due at 2:00 PM CDT on September 4, 2020.
Questions in regards to this combined synopsis/solicitation are due at 3:00 PM CDT on August 21, 2020. Answers to any questions received by that time will be posted as an amendment to this combined synopsis/solicitation.
12505B20R1012731 Department of Agriculture Agricultural Research Service Field Research Implementation and Information Delivery Midwest Area
8/14/20, 7:23 AM Base year and two (2) option years’ service contract for an Environmental Scanning Electron Microscope (ESEM)
1. Class Code: AJ
2. NAICS Code: 811219
3. Subject: Base year and two (2) option years’ service contract for an Environmental Scanning Electron Microscope (ESEM)
4. Solicitation Number: W911QX20Q0118
5. Set-Aside Code: N/A
6. Response Date: Five (5) Days After Posting
7. Place of Delivery/Performance:
U.S. Army Research Laboratory
2800 Powder Mill Road
Adelphi, MD 20783-1138
8.
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.
INTENT TO SOLICIT ONLY ONE SOURCE
The proposed contract action is for supplies or services for which the Government is soliciting and negotiating with only one source under the authority of FAR 13.106-1(b)(1)(i). The name of the company the Government intends to award a contract to is FEI Company, 5350 N.E. Dawson Creek Drive, Hillsboro, OR 97124-5793; (CAGE Code: 1FJ95). This notice of intent is not a request for competitive proposals. However, the Government will consider all proposals received prior to the closing date and time of this solicitation.
(ii) The solicitation number is W911QX20Q0118. This acquisition is issued as an Request for Quote (RFQ).
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2020-06 May 6, 2020.
(iv) The associated NAICS code is 811219. The small business size standard is $22,000,000.00 dollars.
(v) The following is a list of contract line item number(s) (CLIN) and items, quantities and units of measure, (including option(s), if applicable):
CLIN 0001: ESEM Base year service contract
CLIN 0002: ESEM Option year one (1) service contract
CLIN 0003: ESEM Option year two (2) service contract
(vi) Description of requirements: The Government requires maintenance and repair services for a government owned Environmental Scanning Electron Microscope as indicated in section v, located in Adelphi, MD 20783-1138.
(vii) Delivery: Base year period of performance one (1) year after contract award, option year one (1) will be exercised at the end of base year period of performance, and option year two (2) after exercising option and the end of option year one (1) period of performance. Performance shall be made at US Army Research Laboratory, 2800 Powder Mill Road, Building #207, Adelphi, MD 20783-1138. Acceptance shall be performed at Adelphi, MD 20783-1138.
(viii) The provision at 52.212-1, Instructions to Offerors – Commercial DEVIATION 2018-O0018, applies to this acquisition. The following addenda have been attached to this provision: NONE.
(ix) Offerors shall include a completed copy of the provision at FAR 52.212-3 (with its Alternate I), Offeror Representations with its offer.
(x) The clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition. The following addenda have been attached to this clause NONE.
(xi) The clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items and the selected clauses listed in DFARS 212.301 Solicitation provisions and Contract Clauses for the Acquisition of Commercial Items, applies to this acquisition. The following additional FAR/DFARS clauses cited in this clause are applicable:
FAR:
52.204-10: REPORTING EXECUTIVE COMPENSATION AND FIRST-TIER SUBCONTRACT AWARDS (OCT 2016)
52.209-6: PROTECTING THE GOVERNMENT’ INTEREST WHEN SUBCONTRACTING WITH CONTRACTORS DEBARRED, SUSPENDED, OR PROPOSED FOR DEBARMENT (OCT 2015)
52.219-28: POST-AWARD SMALL BUSINESS PROGRAM REREPRESENTATION (JUL 2013)
52.222-3: CONVICT LABOR (JUN 2003)
52.222-21: PROHIBITION OF SEGREGATED FACILITIES (APR 2015)
52.222-26: EQUAL OPPORTUNITY (SEP 2016)
52.222-36: AFFIRMATIVE ACTION FOR WORKERS WITH DISABILITIES (JUL 2014)
52.222-50: COMBATING TRAFFICKING IN PERSONS (MAR 2015)
52.222-51: EXEMPTION FROM APPLICATION OF THE SERVICE CONTRACT LABOR STANDARD TO CONTRACTS FOR MAINTENANCE, CALIBRATION, OR REPAIR OF CERTAIN EQUIPMENT—REQUIREMENTS (MAY 2014)
52.222-53: EXEMPTION FROM APPLICATION OF THE SERVICE CONTRACT ACT TO CONTRACTS FOR CERTAIN SERVICES—REQUIREMENTS (MAY 2014)
52.223-18: ENCOURAGING CONTRACTOR POLICIES TO BAN TEXT MESSAGING WHILE DRIVING (AUG 2011)
52.225-13: RESTRICTIONS ON CERTAIN FOREIGN PURCHASES (JUN 2008)
52.232-33: PAYMENT BY ELECTRONIC FUNDS TRANSFER—CENTRAL CONTRACTOR REGISTRATION (JUL 2013)
52.232-36: PAYMENT BY THIRD PARTY (MAY 2014)
DFARS:
*252.203-7005: REPRESENTATION RELATING TO COMPENSATION OF FORMER DOD OFFICIALS (NOV 2011)
*252.204-7008: COMPLIANCE WITH SAFEGUARDING COVERED DEFENSE INFORMATION CONTROLS (OCT 2016)
252.204-7015: DISCLOSURE OF INFORMATION TO LITIGATION SUPPORT CONTRACTORS (MAY 2016)
*252.204-7016: COVERED DEFENSE TELECOMMUNICATIONS EQUIPMENT OR SERVICES—REPRESENTATION (DEC 2019)
*252.204-7017: PROHIBITION ON THE ACQUISTION OF COVERED DEFENSE TELECOMMUNICATIONS EQUIPMENT OR SERVICES—REPRESENTATION (DEC 2019)
252.204-7018: PROHIBITION ON THE ACQUISITION OF COVERED DEFENSE TELECOMMUNICATIONS EQUIPMENT OR SERVICES (DEC 2019)
252.223-7008: PROHIBITION OF HEXAVALENT CHROMIUM (JUN 2013)
252.232-7010: LEVIES ON CONTRACT PAYMENTS (DEC 2006)
252.237-7010: PROHIBITION ON INTERROGATION OF DETAINEES BY CONTRACTOR PERSONNEL (JUN 2013)
252.244-7000: SUBCONTRACTS FOR COMMERCIAL ITEMS (JUN 2013)
252.247-7023: TRANSPORTATION OF SUPPLIES BY SEA (APR 2014)
(xii) The following additional contract requirement(s) or terms and conditions apply (full text of all FAR/DFARS clauses that contain fill-in information, as well as all local clauses, can be found in the attached Provisions and Clauses Full-Text document):
FAR/DFARS:
*52.204-7: SYSTEM FOR AWARD MANAGEMENT
52.204-13: SYSTEM FOR AWARD MANAGEMENT MAINTENANCE
*52.204-16: COMMERCIAL AND GOVERNMENT ENTITY CODE REPORTING (JUL 2016)
52.204-18: COMMERCIAL AND GOVERNMENT ENTITY CODE MAINTENANCE (JUL 2016)
52.204-21: BASIC SAFEGUARDING OF COVERED CONTRACTOR INFORMATIONS SYSTEMS (JUN 2016)
*52.204-24: REPRESENTATION REGARDING CERTAIN TELECOMMUNICATIONS AND VIDEO SURVEILLANCE SERVICES OR EQUIPMENT (DEC 2019)
52.232-40: PROVIDING ACCELERATED PAYMENTS TO SMALL BUSINESS SUBCONTRACTORS (DEC 2013)
252.201-7000: CONTRACTING OFFICER’S REPRESENTATIVE (DEC 1991)
252.203-7000: REQUIREMENTS RELATING TO COMPENSATION OF FORMER DOD OFFICIALS (SEP 2011)
252.204-7000: DISCLOSURE OF INFORMATION (OCT 2016)
252.232-7003: ELECTRONIC SUBMISSION OF PAYMENT REQUESTS AND RECEIVING REPORTS (JUN 2012)
FAR/DFARS FILL-IN CLAUSES:
*52.252-1: SOLICITATION PROVISIONS INCORPORATED BY REFERENCE (FEB 1998)
52.252-2: CLAUSES INCORPORATED BY REFERENCE (FEB 1998)
252.232-7006: WIDE AREA WORKFLOW PAYMENT INSTRUCTIONS (DEC 2018)
ADELPHI LOCAL CLAUSES:
ACC - APG POINT OF CONTACT
CONTRACTING OFFICER REP
TYPE OF CONTRACT
*INTENT TO SOLICIT ONLY ONE SOURCE
CONTRACTOR MANPOWER REPORTING
NON-PERSONAL SERVICES
AT-OPSEC REQUIREMENTS
DISTRIBUTION STATEMENT A
GOVERNMENT INSPECTION AND ACCEPTANCE
EXERCISE OF OPTION
PAYMENT OFFICE (BANKCARD - INVOICES REQUIRED)
TAX EXEMPTION CERTIFICATE (ARL)
RECEIVING ROOM – ALC
PAYMENT INSTRUCTIONS
SUPERVISION OF EMPLOYEES
WORK HOURS
ID OF CONTRACTOR EMPLOYEES
GOVT-CONTRACTOR RELATIONSHIPS
KEY PERSONNEL
DFARS COMMERCIAL CLAUSES
*EXCEPTIONS OR CONDITIONS CONTAINED IN OFFEROR'S PROPOSAL
*AWARD OF CONTRACT
*ADELPHI CONTRACTING DIVISION WEBSITE
*FOREIGN NATIONALS PERFORMING
*PAYMENT TERMS
(xiii) This acquisition is rated under the Defense Priorities and Allocations System (DPAS) as N/A.
(xiv) The following notes apply to this announcement: The Government is contemplating a commercial firm-fixed price (FFP) contract type for this requirement under FAR Part 13 Simplified Acquisition Procedures (SAP). In accordance with FAR 32.003, contract financing cannot not be provided for this acquisition.
(xv) Offers are due five (5) days after posting, by 11:59 AM EST, by email to Contract Specialist, Dale Brunson dale.m.brunson.civ@mail.mil.
(xvi) For information regarding this solicitation, please contact Contract Specialist, Dale Brunson dale.m.brunson.civ@mail.mil.
W911QX20Q0118 Department of the Army Materiel Command Army Contracting Command Aberdeen Proving Ground
6/15/20, 9:40 AM