Production of large populations of hematopoietic stem cells (hscs) in microgravity to treat serious medical conditions including blood cancers (leukemias, lymphomas, multiple myeloma), fatal blood…
Active Awarded Last action
- Contract number
- 80JSC022F0146
- Awardee
-
The Regents Of The University Of Colorado UEI SPVKK1RC2MZ3
- Awarding agency
-
Johnson Space Center
National Aeronautics and Space Administration
- Obligated
- $3,318,354
Award facts
- Contract value 100% obligated
- $3,318,354.00 Current and potential, with all options
- Completion date 93% complete
- Current and potential, with all options
- Contracting staff
- NAICS code
- 541990 All Other Professional, Scientific, and Technical Services
- Set-aside
- No set-aside
- Competition
- Full and Open Competition Basic Research
- Pricing
- Firm Fixed Price
- Place of performance
- Boulder, CO 80309, USA
- Legislative mandates
-
- Service Contract Act FAR subpart 22.10
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Funding Only Action | $183,354 | |
| Funding Only Action | $285,000 | |
| Other Administrative Action | $0 | |
| Supplemental Agreement for work within scope | $0 | |
| Supplemental Agreement for work within scope | $285,000 | |
| Funding Only Action | $570,000 | |
| Funding Only Action | -$855,000 | |
| Funding Only Action | $855,000 | |
| Funding Only Action | $570,000 | |
| Funding Only Action | $285,000 | |
| Funding Only Action | $285,000 | |
| Funding Only Action | $285,000 | |
| Original award | $570,000 |
Show all 13
About this award
NASA Johnson Space Center awarded The Regents of the University of Colorado a $3.32 million firm fixed-price delivery order on June 6, 2022, to support the production of large populations of hematopoietic stem cells (HSCs) in microgravity for treating serious medical conditions including blood cancers, fatal blood disorders, and severe immune diseases. This delivery order falls under a larger indefinite delivery vehicle with NASA Johnson Space Center focused on space life science research platforms and in-space manufacturing capabilities. The work, to be performed in Boulder, Colorado, with an ultimate completion date of February 20, 2027, represents a non-set-aside competitive award with no small business designation applied. The University of Colorado will leverage its established research capabilities and partnerships to advance this critical biomedical research initiative supporting NASA's life sciences objectives.
The prime contractor has engaged two major subcontractors to execute the project scope. The Regents of the University of Colorado-Denver (operating as ClinImmune Labs) will isolate, purify, and characterize clinical-grade CD34+ stem cells and gene-edited cells, conducting preflight validation and postflight analysis using flow cytometry and functional assays. Mayo Clinic Jacksonville, through Dr. Abba Zubair's team at the Medical Director of Transfusion Medicine and Stem Therapy Laboratory, will generate and analyze HSCs for the project, conduct all preflight validation studies, manage postflight experiments, and prepare scientific manuscripts for peer-reviewed publication. Together, these institutions will develop and validate specialized bioreactor technology for deployment on commercial space stations to expand cord blood and mobilized peripheral blood HSCs collected on Earth, with the ultimate goal of producing cryopreserved stem cell transplant units for clinical use in treating patients worldwide.
Description
Production of large populations of hematopoietic stem cells (hscs) in microgravity to treat serious medical conditions including blood cancers (leukemias, lymphomas, multiple myeloma), fatal blood disorders, and severe immune diseases.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Mayo Clinic Jacksonville (A Nonprofit Corporation) | $68,151 | |
| The Regents Of The University Of Colorado | $54,119 | |
| Mayo Clinic Jacksonville (A Nonprofit Corporation) | $90,000 | |
| The Regents Of The University Of Colorado | $90,000 | |
| Mayo Clinic Jacksonville (A Nonprofit Corporation) | $250,000 | |
| The Regents Of The University Of Colorado | $253,500 |
Quick answers
Who was awarded contract 80JSC022F0146?
80JSC022F0146 was awarded to The Regents Of The University Of Colorado by Johnson Space Center (National Aeronautics and Space Administration) on June 6, 2022.
How much is contract 80JSC022F0146 worth?
The government has obligated $3,318,354 on 80JSC022F0146.
Is contract 80JSC022F0146 an order under another contract?
Yes. 80JSC022F0146 is a delivery order under 80JSC019D0026, an indefinite delivery contract.
Was contract 80JSC022F0146 competed?
The extent of competition for 80JSC022F0146 was full and open competition.
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