Upstream Prevention Inc.
Greenwood, IN
- UEI
- TD5XAABM9954
- CAGE
- 7JVH0
- Primary NAICS
- Not on record
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Tax Exempt)
- SAM.gov registration date
- Physical address
- 530 US 31 S, Greenwood, IN 46142, USA
- Website
- upstreamprevention.org
- Founded
- 2015
- Employees
- 1-10
- Estimated annual revenue
- $0-$1M
- Industry
-
- Consumer Discretionary
- Consumer Services
- Diversified Consumer Services
- Specialized Consumer Services
- SIC code
- 86 Membership Organizations
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Grant awards
Latest 5 listed here. See the rest on GovTribe.
Grant subawards
| Prime recipient | Prime award | Amount | Awarded |
|---|---|---|---|
| Department Of Education Indiana | H79SM080975 | $1,000 | |
| Indiana Department Of Health | NU17CE010220 | $95,000 | |
| Indiana Department Of Health | NU17CE010220 | $190,000 | |
| Indiana Department Of Health | NU17CE010220 | $95,000 |
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| Power Of Putnam, Inc. | Cookeville, TN | — |
| Community Prevention Resources Of Warren County, Inc. | Slatington, PA | 813319 Other Social Advocacy Organizations |
| Porter County Substance Abuse Council | Valparaiso, IN | — |
| Inc.tion National African American Drug Policy | Washington, DC | 813319 Other Social Advocacy Organizations |
About the company
Upstream Prevention Inc., a woman-owned nonprofit based in Greenwood, Indiana, serves as a federal grant recipient delivering youth substance abuse prevention services under SAMHSA and CDC grant programs. The organization operates as a prime grant recipient (67% of recent awards) and as a sub-recipient on state health department pass-through grants (33%), with no federal contract prime footprint.
Upstream Prevention's customer base concentrates entirely within the Department of Health and Human Services. The organization has worked with the CDC and SAMHSA across nine awards spanning 2016 through 2026, with combined obligated dollars of $4.1 million. The largest and most recent award is a $180,000 Project Grant from SAMHSA's Center for Substance Abuse Prevention under the Substance Abuse and Mental Health Services Projects of Regional and National Significance program (CFDA 93.243), dated September 30, 2025, running through September 29, 2029. As fiscal agent for the Empower Johnson County STOP Act initiative, Upstream Prevention will deliver comprehensive youth substance abuse prevention throughout Johnson County, Indiana (population 167,000), with emphasis on reducing alcohol use among middle and high school students. Deliverables include peer-to-peer prevention messaging developed by the Empowered Youth Coalition, community educational opportunities, substance-free youth and family events, participation in local government meetings, and updated prevention programming. Measurable outcomes target maintaining baseline community awareness of youth substance abuse issues, increasing protective factors related to community rewards for prosocial involvement by 16 percentage points among 8th and 10th grade students, and reducing past 30-day alcohol use among 8th graders from 6% to 5% and among 10th graders from 19% to 17%. Upstream Prevention also operates as a sub-recipient on three Overdose Data to Action grants pass-through from the Indiana Department of Health (September 2024, March 2024, and February 2026), funded under CDC authority. The organization faces one recompete event within the next twenty-four months.
Quick answers
Is Upstream Prevention Inc. registered in SAM.gov?
Yes. Upstream Prevention Inc.'s SAM.gov registration is active through January 26, 2027.
What is Upstream Prevention Inc.'s most recent federal award?
Upstream Prevention Inc.'s most recent federal grant award is Empower stop act 2025 application - upstream prevention, INC. Is proud to serve as the fiscal agent for empower johnson… (H79SP084947), from SAMHSA Division of Grants Management, on September 30, 2025.
On GovTribe
See Upstream Prevention Inc.'s full federal record
- Federal grant awards
- Funding analysis by agency, NAICS and set-aside
- Similar vendors