Two Six Labs, LLC

Two Six Labs, LLC, doing business as Two Six Technologies, is a mission-focused cybersecurity and advanced technology solutions provider headquartered in Arlington, Virginia. The company specializes in research and development services for defense and intelligence agencies, with particular expertise in artificial intelligence, secure communications, data science, systems modeling and simulation, and prototype development. Two Six Labs serves as a key contractor for the federal government, delivering innovative technological solutions that support national security objectives across multiple defense and intelligence domains. Registered in SAM.gov since February 2006, the company operates as a for-profit limited liability corporation and maintains a robust portfolio of federal contract vehicles and indefinite delivery/indefinite quantity agreements that position it as a premier provider of advanced research and development capabilities.

Two Six Labs has executed an extensive portfolio of prime federal contracts valued at over $400 million, demonstrating sustained engagement with the Defense Advanced Research Projects Agency (DARPA), Department of Defense, and related federal agencies. The company's contract work encompasses sophisticated research initiatives including the Provably Weird Network Deployment and Detection (PWND2) program ($7.24 million), the Intelligent Generation of Tools for Security (INGOTS) program ($18.6 million), the MOUNTAIN program ($11.5 million), the CHALLAH program ($3.8 million), the HANDOFF BRATISLAVA program ($12.6 million), the EMBERS program ($13.9 million), the CARCOSA program ($26.4 million), the Resilient Supply-Demand Networks (RSDN) program ($7.0 million), the WICKET project ($2.97 million), the MIMESIS program ($11.9 million), and the CAMO program ($6.64 million). These contracts are predominantly cost-plus-fixed-fee definitive contracts with DARPA, reflecting the research-oriented nature of the work and the technical complexity involved. The company has also received significant contract awards from the Office of Naval Research, Defense Threat Reduction Agency, Department of Homeland Security, Office of the Secretary of Defense, and Air Education and Training Command. Through subsidiary IST Research, LLC, Two Six Labs has secured substantial SBIR Phase III delivery orders across multiple Department of Defense agencies including the Marine Corps, Army, Navy, Air Force, Special Operations Command, and Intelligence and Security Command, supporting the development and deployment of the IST PULSE platform—a cloud-based software-as-a-service system for data collection, analysis, and intelligence capabilities. Two Six Labs frequently collaborates with established subcontractors including Systems & Technology Research LLC, Leidos, Inc., Applied Research Associates, Inc., HII Mission Technologies Corp, and academic institutions such as New York University, enabling comprehensive technical solutions across distributed research domains. Prime contract awards typically do not utilize set-aside designations, reflecting the specialized and unrestricted nature of the research and development services provided.

Two Six Labs has provided federal grant funding support primarily through DARPA contracts that include subgrant components to academic partners, particularly New York University. Under the MIMESIS program, Two Six Labs issued subgrants to New York University for developing self-sustaining, adaptive, and scalable methods for generating causal system models based on local knowledge to support operational decision-making in non-Western populations. The subgrant awards to NYU, valued at approximately $124,000 in total across multiple award dates (August 2022 and January 2024), supported critical research tasks including data collection and provision efforts, threat model development, and challenge problem curation. These subgrant activities required NYU to provide an effective labor and skill mix encompassing subject matter experts, data scientists, UI engineers, and intelligence analysts to accomplish tasks specified in detailed statements of work. The funding supported monthly status reporting, ongoing data collection execution for synthetic content corpus development, and coordination of analysis, annotation, and threat model insights. Through this grant substructure, Two Six Labs leveraged academic research capabilities to enhance the scientific rigor and innovation potential of its primary DARPA research initiatives, demonstrating the company's integration of external expertise within its broader research portfolio.

Two Six Labs maintains an extensive portfolio of federal contract indefinite delivery/indefinite quantity (IDIQ) vehicles that provide government-wide acquisition frameworks for rapidly procuring specialized technical services. The company holds the OASIS+ Unrestricted Multiple Agency Contract (MAC) under the General Services Administration's Federal Acquisition Service, with a ceiling value of $999,999,999,999.00 extending through December 16, 2029, enabling federal agencies across civilian and defense sectors to rapidly acquire Two Six Labs' professional services and research and development solutions. Two Six Labs was awarded a Defense Threat Reduction Agency (DTRA) Indefinite Delivery/Indefinite Quantity contract on May 30, 2024, under the Combating Weapons of Mass Destruction (CWMD) 2024-2029 master IDIQ vehicle, with a four-billion-dollar ceiling value and an ultimate completion date of May 29, 2029. This multiple-award, non-set-aside contract provides for research, development, test and evaluation, procurement, maintenance, support, systems engineering, and sustainment services aligned with Department of Defense CWMD priorities. Two Six Labs also holds an Other Transaction IDV awarded by DARPA on July 17, 2025, valued at $28.8 million, supporting the Rapid Resilience Responses (R3) program, specifically the Advanced Resilience Through Enduring Missions (ARTEMIS) program and related resilience research efforts. Additional Other Transaction IDVs include the PROVABLY WEIRD NETWORK DEPLOYMENT AND DETECTION (PWND2) IDV ($1,085,037), the TWO SIX PROTOTYPE IDIQ ($983,843) awarded by Department of Defense Washington Headquarters Service, and a DARPA CLAMPED IDIQ contract ($999,271) for privacy-preserving machine learning services utilizing homomorphic encryption. These IDV vehicles support Two Six Labs' core competencies in cybersecurity, artificial intelligence, secure communications, automated reasoning, and systems modeling and simulation, enabling rapid task order acquisition by federal agencies and supporting the company's role as a strategic provider of advanced technological solutions for national security objectives.