Tufts Medical Center Parent, Inc.

Tufts Medical Center Parent, Inc., doing business as Tufts Medical Center, is a non-profit tax-exempt academic medical center based in Boston, Massachusetts, that acts as both a prime recipient and subrecipient on federal grants and as a prime contractor on federal service contracts, with 71% of recent awards in prime roles across healthcare delivery, clinical research, and biomedical research spanning 53 customer agencies. The organization does not operate under any SBA set-aside designation and competes in full-and-open federal grant and contract vehicles.

Tufts Medical Center's portfolio divides cleanly between clinical service contracts routed through the Department of Veterans Affairs and a dominant grant footprint anchored in the National Institutes of Health. On the contract side, the organization holds a single-award Blanket Purchase Agreement with Veterans Integrated Service Network 1 (VISN 1) for eye pathology testing services—a $296 thousand vehicle established in October 2023 and running through October 2028, under which three calls totaling $90 thousand have been issued. A recent July 2026 educational cost contract with VISN 1 carries $39.218 thousand with a five-year performance window through June 2030. These contracts reflect specialized ophthalmic pathology and diagnostic capabilities delivered at Tufts Medical Center in Jamaica Plain and Boston.

The grant portfolio is substantially larger. The National Institutes of Health accounts for 202 awards, with the National Institute on Aging (56 awards), National Heart Lung and Blood Institute (44 awards, $5.4 million combined potential value), and National Cancer Institute (32 awards, $3.8 million combined potential value) as leading NIH components. However, the Agency for Healthcare Research and Quality (AHRQ) leads on dollar magnitude with 26 awards carrying $20.6 million in combined potential value. Representative recent grant work spans cardiovascular and metabolic research—a $889.728 million National Institute on Aging award (August 2026) for circuit-based multi-focal neurostimulation targeting depression and memory in older adults with Alzheimer's dementia; a $357 thousand NIA award (September 2026) investigating endothelial pannexin1-induced inflammation in Alzheimer's disease; a $490.875 thousand National Eye Institute award (August 2026) for genome-wide association studies on steroid-induced ocular hypertension and glaucomas; and an $8.296 million NIA Cooperative Agreement (July 2026) for an advance care planning educator video program for older adults and those with dementia. Tufts Medical Center also holds project grants from the National Heart Lung and Blood Institute, National Institute of Neurological Disorders and Stroke, National Institute of Allergy and Infectious Diseases, and the Defense Health Agency, with work spanning babesiosis vaccine development, vascular biology, neurodegenerative disease mechanisms, and chemical exposure countermeasures.

Recent contract activity shows annual award volume of 26 to 76 awards across 2022–2026, with 2024 representing a peak year at 76 awards. The organization faces 26 awards with completion dates in the next twenty-four months, carrying combined potential value of $80 thousand—a modest recompete window relative to the overall grant-dominant portfolio. Tufts Medical Center subcontracts to prime grantees including The General Hospital Corporation (Massachusetts General Hospital) on Lyme disease surveillance work, Boston University Trustees on CARB-X antibacterial research, and numerous academic medical centers and research institutions on NIH-funded collaborative studies. In its subgrant role, Tufts Medical Center provides research infrastructure, statistical analysis, clinical trial coordination, and scientific leadership across studies led by Brown University, Columbia University, Mayo Clinic, Northwestern University, and other research centers, with investigators contributing expertise in biostatistics, clinical informatics, obstetrics and gynecology, cardiology, and gerontology.

The organization's federal footprint is entirely grant and contract work; it does not hold positions on government-wide IDIQs, GWACs, or agency-wide vehicles beyond the single-award VISN 1 eye pathology BPA. Its activity trajectory is stable, with annual award volume ranging 26 to 76 across the past five years. Work is performed in Boston, Massachusetts, with administrative offices at 800 Washington Street.