Sciome LLC

Sciome LLC, a minority-owned small business specializing in bioinformatics, computational toxicology, and data science software, operates as a 100% prime contractor to federal research and civilian agencies. Based in Durham, North Carolina, Sciome is a for-profit limited liability company with Subcontinent Asian American ownership; it competes exclusively in full-and-open and sole-source procurements with no set-aside designation across its recent award footprint.

The National Institute of Environmental Health Sciences dominates Sciome's customer concentration, accounting for 9 awards valued at $52.9 million in combined potential value—roughly 98% of the vendor's total award portfolio. NIEHS procures Sciome's bioinformatics analysis, biostatistical programming, mathematical modeling, and computational support services through definitive contracts and delivery orders under the GSA Multiple Award Schedule. Sciome's two most significant active awards are a $26.23 million definitive contract for bioinformatics support to NIEHS's Divisions of Translational Toxicology and Intramural Research (awarded September 24, 2024, with completion targeted for March 23, 2032) and a $4.9 million delivery order for BCBB statistical programming support under GSA MAS (awarded September 30, 2023, through September 29, 2028). A completed $5.55 million sole-source definitive contract for bioinformatics support to NIEHS's Division of the National Toxicology Program and Division of Intramural Research (September 24, 2022 through September 23, 2024) illustrates Sciome's incumbent supplier position. The National Oceanic and Atmospheric Administration represents the second-largest customer with three awards totaling $358 thousand, including a sole-source purchase order for Swift-Active Screener enterprise-level licenses (August 17, 2026 through August 16, 2030 for $178,781), a software system Sciome manufactures and distributes exclusively. The Environmental Protection Agency's Office of Research and Development has awarded two task orders totaling $320 thousand for data extraction models and computational support.

Sciome holds a seat on the GSA Multiple Award Schedule with four task orders generating $7.6 million in combined potential value. The vendor's GSA labor portfolio spans thirty categories priced from $46.80 to $324.41 per hour, ranging from bachelor's-degree project specialists to PhD-level subject matter experts, with no security-cleared positions. Government-paid median hourly rates on SCI-reportable prime contracts run $117.42 per hour, with the 90th percentile at $137.48 per hour, consistent with scientific and programming labor positioning.

SCI-reported invoicing across prime contracts totaled $8 million over fiscal years 2022 through 2024 (FY2022: $2.4 million across 10.4 FTEs; FY2023: $2.7 million across 11.2 FTEs; FY2024: $2.9 million across 11.7 FTEs). Sciome self-performs 100% of contracted work on SCI-reportable service contracts with zero subcontractor engagement. The vendor recently held a $249,943 research grant from NIEHS (awarded September 1, 2023, completing August 31, 2025) to develop ToxGraph, an adverse outcome pathway-focused mechanistic inference tool for omics data analysis using semantic knowledge graphs and deep learning. Activity has been uneven—two awards in 2021, four in 2022, two in 2023, one in 2024, and one in 2026—with only one award (the NOAA Swift-Active Screener license order valued at $153 thousand) reaching ultimate completion inside the next twenty-four months. The vendor's $54.2 million combined potential value across all awards reflects a deep NIEHS incumbent position anchored by two long-duration definitive contracts spanning the next several years.