Project Grant R01AI194318
- The U.S. National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,166,933 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Vanderbilt University Medical Center to study Mycobacterium tuberculosis transmission. The project aims to identify bacterial genetic and phenotypic features associated with M. tuberculosis transmission outcomes, including infection, subclinical TB, and clinical TB disease. It will also define M. tuberculosis...
- This Project Grant award of $375,996.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to assess the potential carriage state of Mycobacterium tuberculosis (MTB) in the upper respiratory tract of individuals who have been exposed to tuberculosis (TB) but do not display active disease. The research aims to understand the mechanisms by which the majority of people...
- This $193,375 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to identify bacterial determinants that may contribute to variable treatment responses for tuberculosis (TB). The project, conducted by researchers at the Harvard T.H. Chan School of Public Health, aims to investigate the effects of clinically prevalent variants in the ESX1 secretion system on TB...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,041,944 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Rutgers, The State University of New Jersey. The grant will support research to understand the mechanisms underlying heterogeneous transmission of Mycobacterium tuberculosis (MTB) strains, as well as the immune responses of individuals who resist MTB infection despite exposure. The research aims to identify potential...
- This Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID, CFDA 93.855 Allergy and Infectious Diseases Research), provides $466,500.00 in funding to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on the bacterial genetic basis underlying the transmissibility of tuberculosis (TB). The project aims to: (1) identify key mutations that drive high transmissibility in Mycobacterium tuberculosis (MTB) using a global collection of...
- This federal Project Grant award of $1,141,359 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research to investigate the mechanisms underlying tuberculosis (TB) transmission, with a focus on understanding how host and bacterial factors influence the cough reflex and aerosolization of Mycobacterium tuberculosis (MTB). The project aims to analyze the impact of biological...
- This $190,892 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will support a study to optimize tuberculosis (TB) active case finding strategies in Nairobi, Kenya. The key products and services to be delivered include: Employing multiple data sources on human mobility and activity spaces to identify high-yield geographic locations for TB screening within Nairobi. Developing a geospatial model to estimate...
- This Project Grant award of $821,087 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research to examine the relationship between latent tuberculosis infection (LTBI) and the risk of developing diabetes mellitus and cardiovascular disease. The key objectives are to: 1) Estimate the association between LTBI and indicators of diabetes and cardiovascular disease; 2) Determine if established...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $429,546 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to National Jewish Health in Colorado. The grant will fund research to evaluate the efficacy of tuberculosis (TB) treatment regimens by analyzing the transcriptomic patterns of Mycobacterium tuberculosis injury and adaptation during drug treatment. The research aims to develop more reliable preclinical measures of TB treatment...
- This Project Grant award of $104,262, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to explore the relationship between genetic variants, transcriptional responses, and tuberculosis (TB) infection outcomes in macrophages derived from genetically diverse mice. The project aims to understand the basis for variability in TB infection outcomes, which may help identify ways to...
This $1,173,748.00 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research on the role of asymptomatic tuberculosis (TB) in disease transmission. The research aims to improve understanding of when individuals become infectious and where transmission is occurring, particularly in community settings outside of household contacts. Key areas of focus include characterizing infectiousness during the asymptomatic stage of TB and analyzing social contact patterns during early stages of the disease. The research will be conducted by Emory University in Atlanta, GA, and is expected to run from September 16, 2025 through August 31, 2030. Findings from this project have the potential to inform innovative strategies for halting TB transmission at the population level.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/23/25 | ||
| Not listed | $1.2m | 9/16/25 |