Openeye Scientific Software, Inc.
Santa Fe, NM Part of Cadence Design Systems Inc.
- UEI
- NUUHK6HHEW91
- CAGE
- 3WAW7
- Primary NAICS
- 513210 Software Publishers
- SAM.gov registration
- Active through
Company facts
- FY2025 rankings
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Its parent company, Cadence Design Systems Inc., ranks:
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Not Tax Exempt)
- Other NAICS codes in SAM.gov
- Corporate family
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-
Parent
San Jose, CA
NC1VVZ3DJ3K4
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Parent
San Jose, CA
NC1VVZ3DJ3K4
- SAM.gov registration date
- Physical address
- 9 Bisbee Ct d, Santa Fe, NM 87508, USA
- Website
- eyesopen.com
- Founded
- 1997
- Employees
- 51-250
- Estimated annual revenue
- $1B-$10B
- Industry
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- Information Technology
- Software & Services
- Internet Software & Services
- SIC code
- 73 Business Services
- Profiles
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Contract obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2027 To date | $0 |
| FY2026 | $140,816 |
| FY2025 | $82,910 |
| FY2024 | $126,212 |
| FY2023 | $118,202 |
Top agencies by obligations
| Rank | Agency | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | Department of Health and Human Services | $140,816 |
Contract awards
Latest 5 listed here. See the rest on GovTribe.
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About the company
Openeye Scientific Software, Inc., a subsidiary of Cadence Design Systems Inc., sells computational chemistry and molecular modeling software licenses and toolkit maintenance to federal research agencies as a prime contractor, competing on full-and-open, no-set-aside purchase orders. The company is a for-profit corporate entity headquartered in Santa Fe, New Mexico, and carries primary NAICS classifications in Software Publishers and Other Computer Related Services, with a Federal Procurement Data System footprint dominated by Information Technology Software (PSC) codes.
Openeye's federal capability portfolio centers on proprietary cheminformatics and molecular screening software—toolkits including OMEGA, ROCS, SZMAP, FILTER, BROOD, EON, SITEHOPPER, SZYBKI, OEDocking, QUACPAC, SPRUCE, VIDA, and OEChem TK—deployed for drug discovery, virtual screening, structure-activity relationship analysis, and computational chemistry research. Recent awards exemplify the work: a $274 thousand purchase order from the National Library of Medicine issued July 24, 2026 for toolkit maintenance and annual renewal support running through July 2029; a $53.8 thousand purchase order from the National Center for Advancing Translational Sciences (June 15, 2026) covering annual subscriptions to the OpenEye Non-Profit Package, FastROCS evaluation license, and Shape evaluation license; and a $237.1 thousand firm fixed-price purchase order from the National Library of Medicine (July 7, 2023) for renewal of Lexichem TK, OEChem TK, and Quacpac TK licenses supporting PubChem research infrastructure.
Customer concentration is narrow and stable. The top two customer agencies—the National Library of Medicine (7 awards, $1.8 million combined potential value) and the National Institute of Environmental Health Sciences (9 awards, $1.2 million)—account for 16 of 37 total awards and 62% of the award count, covering 84% of combined potential value across the portfolio. These two agencies anchor the National Institutes of Health ecosystem; the National Center for Advancing Translational Sciences, NIH proper, and the National Heart Lung and Blood Institute round out the active customer set. All ten distinct customer agencies served fall within the Department of Health and Human Services. No parent contract vehicles (GWACs, IDIQs, BPAs) appear in the portfolio; all awards are direct purchase orders from end-using agencies.
Activity has been episodic and low-volume. The past five years show one to two awards annually (2020, 2021, 2023, 2024, 2026), with 37 total awards and $4.2 million combined potential value since the first award in 2004. Combined dollars obligated stand at $4 million (94% of potential value), indicating execution-stage performance. Only one award ($54 thousand) reaches ultimate completion inside the next twenty-four months, yielding minimal recompete exposure in that window. Openeye competes exclusively on full-and-open solicitations with no set-aside designation across the prime footprint, and operates with no documented subcontract engagements in the federal space.
Quick answers
Is Openeye Scientific Software, Inc. registered in SAM.gov?
Yes. Openeye Scientific Software, Inc.'s SAM.gov registration is active through June 4, 2027.
How much has Openeye Scientific Software, Inc. received in federal contracts?
Federal contracts obligated $82,910 to Openeye Scientific Software, Inc. in fiscal year 2025 and $468,139 in fiscal years 2023 through 2027.
How does Openeye Scientific Software, Inc. rank among federal contractors?
Openeye Scientific Software, Inc.'s parent company, Cadence Design Systems Inc., ranked #26 at the Defense Microelectronics Activity, #82 in NAICS 5132 and #91 in NAICS 513 in FY2025.
What is Openeye Scientific Software, Inc.'s most recent federal award?
Openeye Scientific Software, Inc.'s most recent federal contract award is Openeye scientific software INC:1124148 [26-001015] toolkit maintenance (75N98026P01111), from Office of Logisitics and Acquisition Operations (NIH), on July 24, 2026.
On GovTribe
See Openeye Scientific Software, Inc.'s full federal record
- Federal contract awards
- Funding analysis by agency, NAICS and set-aside
- Similar vendors