Isomics Inc.
Cambridge, MA
- UEI
- V1M9ZMG8APN3
- CAGE
- 4YEQ9
- Primary NAICS
- 541511 Custom Computer Programming Services
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Not Tax Exempt)
- SAM.gov registration date
- Physical address
- 55 Kirkland St, Cambridge, MA 02138, USA
- Website
- isomics.com
- Employees
- 1-10
- Estimated annual revenue
- $0-$1M
- Industry
-
- Information Technology
- Software & Services
- Internet Software & Services
- SIC code
- 73 Business Services
- Profiles
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Grant subawards
| Prime recipient | Prime award | Amount | Awarded |
|---|---|---|---|
| Brigham & Womens Hospital Inc. | R01CA310962 | $164,174 | |
| University Of North Carolina At Chapel Hill | R01DE024450 | $80,000 | |
| Brigham & Womens Hospital Inc. | R01CA235589 | $297,710 | |
| Brigham & Womens Hospital Inc. | R01MH136160 | $71,906 |
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About the company
Isomics Inc., a Cambridge, Massachusetts–based medical-imaging software company, operates exclusively as a grant sub-recipient on National Institutes of Health research programs, with no prime contract or direct federal procurement footprint. The Subchapter S corporation functions as an investigator-led technology partner in academic-industry collaborations, contributing specialized expertise in 3D medical image analysis, deep learning, and software integration rather than pursuing federal contracts as a prime.
Isomics holds a research-stage position anchored by Dr. Steven Pieper, the company's founder and CEO, whose 15-year collaboration with the NIH and leading academic medical centers (Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, MIT) frames the vendor's federal engagement. The company specializes in medical image computing, segmentation and measurement software, and the integration of deep neural networks into clinical workflow systems. Pieper's background includes eight years as CTO of Medical Media Systems, where he led development of the Preview system for 3D segmentation in aortic aneurysm planning—software that remains in clinical use over two decades later. Since founding Isomics in 2002, Pieper has maintained joint NIH funding with collaborators and served as a technical leader on the 3D Slicer open-source medical imaging platform, downloaded over 100,000 times annually.
The vendor's federal grant sub-award footprint spans three NIH institutes. Recent work includes a March 2026 sub-award from the University of North Carolina at Chapel Hill (National Institute of Dental and Craniofacial Research) to integrate temporomandibular joint quantification technologies into 3D Slicer, an April 2025 sub-award from Brigham and Women's Hospital (National Cancer Institute) as an industry partner on a Lymph Node Quantification System for multisite clinical trials, and a March 2025 sub-award from Brigham and Women's Hospital (National Institute of Mental Health) to develop deep neural network software for real-time transcranial magnetic stimulation prediction and EEG visualization. Combined federal dollars obligated across the three awards total $410 thousand, with activity concentrated in 2025 and early 2026. The vendor does not bid on IDIQs, GWACs, or agency-wide contract vehicles; federal engagement is limited to investigator-led grant sub-awards through academic institutions.
Quick answers
Is Isomics Inc. registered in SAM.gov?
Yes. Isomics Inc.'s SAM.gov registration is active through January 13, 2027.
On GovTribe
See Isomics Inc.'s full federal record
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