E-Sentience, Inc.

E-Sentience, Inc., doing business as Aegilys, is a woman-owned small disadvantaged business that develops wearable electrochemical sensors and physiological monitoring systems for military personnel performance optimization as a prime contractor exclusively under Total Small Business set-asides. The North Bethesda, Maryland-based firm competes entirely as a prime across SBIR Phase II programs and direct purchase orders, with no subcontract footprint in the source data.

E-Sentience's capability portfolio centers on noninvasive biomarker detection through wearable sensors designed to assess and maintain cognitive and physiological performance of military airmen and soldiers. The vendor's recent award history spans four contracts, all focused on cortisol and stress-hormone monitoring systems. Representative work includes a $2 million Army definitive contract (awarded September 8, 2025, completion June 8, 2027) for development of a wearable electrochemical sensor that detects cortisol in sweat and transmits real-time data to an edge device; a $1.25 million Air Force Research Laboratory SBIR Phase II purchase order (awarded August 9, 2024, completion April 9, 2026) for a real-time cortisol monitoring system designed to assess airmen cognitive performance; an earlier $1.9 million Army SBIR Phase II definitive contract (awarded September 1, 2023, completion March 1, 2025) for wearable physiological monitoring technologies; and a $74,956 Air Force Research Laboratory purchase order (awarded June 19, 2026, completion September 30, 2026) for a point-of-need salivary alpha amylase sensor to improve airman readiness.

Customer concentration is split evenly between the Department of the Army (two awards, $3.9 million combined potential value) and the Department of the Air Force Materiel Command Research Laboratory (two awards, $1.3 million combined potential value). All four awards are categorized under R&D in the physical, engineering, and life sciences, with two routed through National Defense R&D Services. One award carrying $2 million in potential value completes within the next twenty-four months and faces recompete. Combined obligated value across all awards stands at $5.2 million with no outstanding pipeline beyond the current four-contract set.