Center For Computational Science Research, Inc.

Center For Computational Science Research, Inc. (CCSR), doing business as Open Cloud Consortium, is a nonprofit organization dedicated to supporting research in science, medicine, healthcare, and the environment by providing advanced cyberinfrastructure for open data and open research. The organization operates through three primary divisions: BloodPAC Consortium, Open Commons Consortium, and Data Mining Group, generating revenues through membership fees, grants, and contributions. CCSR specializes in developing and managing cloud computing platforms, data commons, and data meshes that facilitate scientific, medical, and healthcare research, with a particular focus on creating secure, scalable computational environments for complex research initiatives.

In terms of federal contract awards, CCSR has demonstrated capability in providing specialized software and computational services. The most recent contract, a $56,000 firm-fixed-price purchase order from the U.S. Department of the Navy's Office of Naval Research, involved acquiring and maintaining FEFLO software for numerical simulations. As a sub-contractor, CCSR has worked with entities like the University of Chicago on collaborative projects, specifically a pilot study with the Veterans Health Administration to develop a VA Data Commons. This sub-contract involved setting up and operating a Gen3 data commons, developing granular access control mechanisms, importing VA data securely, and providing project management support for creating a scalable, secure research data infrastructure.

For federal grant awards, CCSR has been actively involved in medical research support, particularly in cancer research initiatives. Through sub-awards with The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., CCSR has contributed to projects like the Cancer Moonshot and Prometheus programs. These grants have involved developing data platforms that link multiple data commons, repositories, and data lakes to support research ecosystems. Specifically, through its BloodPAC Consortium division, CCSR has conducted inter-laboratory studies on liquid biopsy research, including projects that examine variance in the analysis of contrived samples, gene variant detection, and collaborative research on oncology biomarkers. These grant-funded efforts have involved partnerships with institutions such as the University of Chicago, the Boston VA, and the Ellison Institute for Transformational Medicine, focusing on creating standardized, high-quality research data environments.