Immunization Cooperative Agreements

Active

Assistance listing
93.268
Agency
Grant awards
501 $6,863,656,310 in federal obligations

Program facts

Also known as
Immunizations CoAg and Vaccines for Children Program previously published as Immunization Grants and Vaccines for Children Program
Assistance types
  • Cooperative Agreement
  • Project Grant
  • Block Grant
Treasury account
  • 75-0943-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Health and Human Services Centers for Disease Control and Prevention funds state and local immunization infrastructure and vaccine distribution through the Immunization Cooperative Agreements program (CFDA 93.268), with the most recent grant awards disbursed as of September 30, 2025, and an active solicitation (CDC-RFA-IP-25-0007) due March 13, 2025.

The program funds establishment and maintenance of preventive health service programs delivering vaccines against measles, rubella, poliomyelitis, diphtheria, pertussis, tetanus, hepatitis B, and other vaccine-preventable diseases. Recent awards show funding for state immunization program operations including vaccine procurement and distribution, provider enrollment and compliance in the Vaccines for Children (VFC) program, immunization information system maintenance, vaccine confidence and education campaigns, outbreak response readiness, and targeted vaccination outreach to underserved and rural populations. Awards support activities across the full vaccination lifespan from perinatal hepatitis B prevention through adult immunization.

Portfolio activity shows 501 awards over more than two decades, with $6.86 billion in combined federal obligations. Awards per year have varied substantially, from 2 awards in 2022 to 19 in 2019 and 18 in 2025. The assistance-type distribution is predominantly Project Grants (88 percent, 440 awards) with a smaller share of Cooperative Agreements (12 percent, 60 awards). All funding concentration appears to rest with the Department of Health and Human Services Centers for Disease Control and Prevention across the portfolio.

Recent awards exemplify the program's scope: Colorado received $23.3 million for vaccine management, provider network expansion, and immunization information system certification; North Carolina received $33.1 million for Section 317 and VFC program operations including provider training and equity-focused vaccination efforts; Arizona received $18.7 million for vaccine access expansion through mobile units and tribal partnership strengthening; Missouri received $18.8 million for vaccine access, misinformation combat, and immunization infrastructure; and Houston received $10.4 million for VFC operations and perinatal hepatitis B prevention.

The current open solicitation (CDC-RFA-IP-25-0007, "Strengthening Vaccine-Preventable Disease Prevention and Response") requires Cooperative Agreement applications from U.S. states, political subdivisions, and other public entities (private individuals and private nonprofits are ineligible). The NOFO mandates application to all three components: Core funding, rapid small-scale outbreak response (funded), and rapid large-scale outbreak response (approved but unfunded). Projects run 1 to 5 years with up to five-year continuation possible on satisfactory progress. Initial budget periods typically run 12 months. The program requires no state match.

Objective and description

Objective

To assist states and communities in establishing and maintaining preventive health service programs to immunize individuals against vaccine-preventable diseases (including measles, rubella, poliomyelitis, diphtheria, pertussis, tetanus, hepatitis B,

Eligibility

Applicant eligibility

Any U.S. state, and in consultation with state health authorities, political subdivisions of states and other public entities and U.S. territories may apply; private individuals and private nonprofit agencies are not eligible for immunization grants.

Beneficiary eligibility

Any U.S. state, political subdivision (as described above), and other public entities will benefit.

Credentials and documentation

Any required credentials and/or documentation will be identified in the specific Notice of Funding Opportunity (NOFO) for this Assistance Listing.

Uses of assistance

Cooperative Agreement funds may be used for costs associated with planning, organizing, and conducting immunization programs directed toward vaccine-preventable diseases and for the purchase of vaccine; and for the implementation of other program elements, such as assessment of the problem; surveillance and outbreak control; information and education; adequate notification of the risks and benefits of immunization; compliance with compulsory school immunization laws; vaccine storage, supply management, and delivery; citizen participation; and use of volunteers. Vaccine will be available "in lieu of cash" if requested by the applicants. Requests for personnel and other items "in lieu of cash" will also be considered. Vaccine purchased with Cooperative Agreement funds may be provided to private practitioners who agree not to charge for vaccine. Cooperative Agreement funds may be used to supplement (not substitute for) existing immunization services and operations provided by a state or locality.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Renewals

Project period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
Strengthening Vaccine-Preventable Disease Prevention and Response CDC-RFA-IP-25-0007 Closed
Immunization and Vaccines for Children CDC-RFA-IP19-19010101SUPP24 Closed
Immunization Barriers in the United States: Targeting Medicaid Partnerships CDC-RFA-IP-23-0002 Closed
Promoting, Strengthening and Enhancing Disease Prevention through Collaboration with Targeted Partnerships CDC-RFA-IP-23-0001 Closed
Improving Standard Immunization Practices Among Pharmacists and Other Healthcare Providers CDC-RFA-IP-23-0003 Closed
Developing and Disseminating Targeted Immunization Materials CDC-RFA-IP21-2104 Closed
Human Papillomavirus (HPV) Roundtable: Supporting a National Network of Partners to Promote Cancer Prevention through Human Papillomavirus Vaccination CDC-RFA-IP21-2105 Closed
Immunization Barriers in the United States: Targeting Medicaid Partnerships CDC-RFA-IP20-2001 Closed
Promoting Research on Music and Health: Fundamentals and Applications (R21 Clinical Trials Optional) RFA-NS-19-009 Closed
Immunization and Vaccines for Children CDC-RFA-IP19-1901 Closed
Improving Standard Immunization Practices Among Pharmacists and Other Healthcare Providers CDC-RFA-IP18-1803 Closed
PPHF 2016 - Immunization - Immunization and Vaccines for Children Program - Financed in Part by 2016 Prevention and Public Health Funds CDC-RFA-IP13-130104PPHF16 Closed
Immunization - Utilization of Immunization Information Systems (IIS) for Assessment, Feedback, Incentives, and eXchange (AFIX) Assessments - financed in part by 2015 Prevention and Public Health Funds CDC-RFA-IP15-1505PPHF15A Closed
Immunization Information Systems (IIS) Sentinel Site Project CDC-RFA-IP13-130204CONT16 Closed
Immunization and Vaccines for Children Program CDC-RFA-IP13-130104CONT16 Closed
Improving Adult Immunization Rates through Partnerships with Providers and National Organizations CDC-RFA-IP15-1503 Closed
Immunization Information Systems (IIS) Sentinel Site Project CDC-RFA-IP14-140702CONT15 Closed
Immunization Information Systems (IIS) CDC-RFA-IP13-130203CONT15 Closed
Show all 18

Grant awards

Award Recipient Federal obligations Awarded
Breathe well: development and implementation of a training program to increase vaccination in early childcare and… U48DP006966 Regents Of The University Of Michigan $394,701
Operation funding for the nevada state immunization program, including nevada webiz and the vaccines for children (VFC)… NH23IP922729 Nevada Department Of Health And Human Services $14,522,265
Strengthening vaccine-preventable disease prevention and response. - the state of nebraska immunization program will… NH23IP922728 Nebraska Department Of Health & Human Services $9,926,384
Strengthening vaccine-preventable disease prevention and response - immunizations are one of the most successful public… NH23IP922725 Minnesota Department Of Health $16,468,204
LOS angeles city immunization cooperative agreements 2025 - vaccination against infectious diseases is one of the… NH23IP922719 County Of LOS Angeles $2,655,638
New mexico department of health immunization program grant application for immunization and vaccines for children… NH23IP922709 State Of New Mexico $15,756,128
Strengthening vaccine-preventable disease prevention and response - the new hampshire immunization program (nhip)… NH23IP922707 New Hampshire Department Of Health & Human Services $7,470,613
The implementation of activities designed to increase immunization coverage rates across idaho and to reduce… NH23IP922703 Idaho Department Of Health & Welfare $13,142,240
Strengthening vaccine-preventable disease prevention and response NH23IP922696 City Of Houston $10,427,585
Strengthening vaccine-preventable disease prevention and response colorado department immunization branch NH23IP922691 Colorado Department Of Public Health & Environment $23,269,617

Latest 10 of 501 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 101 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $198,527,676
FY2025 $395,490,303
FY2024 $298,008,845
FY2023 $864,012,872
FY2022 $647,227,056
FY2021 $7,178,401,038
FY2020 $1,389,136,062
FY2019 $361,631,847
FY2018 $329,002,402
FY2017 $379,583,290
FY2016 $247,574,580
FY2015 $303,636,151
FY2014 $311,097,393
FY2013 $306,724,336
FY2012 $302,967,141
FY2011 $290,876,485
FY2010 $287,141,913
FY2009 $289,825,024
FY2008 $233,101,265
FY2007 $37,555,914
FY2006 $96,753,941
FY2005 $1,458,632
FY2004 $5,493,402
FY2003 $3,677,025
FY2002 $170,008,552
Show all 25

Quick answers

What is Assistance Listing 93.268?

Assistance Listing 93.268 is Immunization Cooperative Agreements, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Immunization Cooperative Agreements?

Its CFDA number is 93.268: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.268 awarded?

501 grant awards under 93.268 have obligated $6,863,656,310 in federal funds to 101 recipients.

Who receives the most funding from 93.268?

The recipients obligated the most under Immunization Cooperative Agreements are California Department Of Public Health ($1,573,417,600), North Carolina Department Of Health & Human Services ($457,744,524) and Michigan Department Of Health And Human Services ($416,725,454).

How much did 93.268 obligate in fiscal year 2025?

Grants under 93.268 obligated $395,490,303 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.268?

No opportunity listed under 93.268 is open now. The latest, Strengthening Vaccine-Preventable Disease Prevention and Response, was posted on August 7, 2024.

On GovTribe

See this program's full record

  • Every grant award and opportunity under it
  • Funding by recipient, agency and assistance type
  • Alerts for new opportunities
  • Ask GovTribe AI about this program