Immunization Cooperative Agreements
Active
- Assistance listing
- 93.268
- Agency
-
Centers for Disease Control and Prevention
Department of Health and Human Services
- Grant awards
- 501 $6,863,656,310 in federal obligations
Program facts
- Also known as
- Immunizations CoAg and Vaccines for Children Program previously published as Immunization Grants and Vaccines for Children Program
- Assistance types
-
- Cooperative Agreement
- Project Grant
- Block Grant
- Treasury account
-
- 75-0943-0-1-550
- More information
Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.
About this program
The Department of Health and Human Services Centers for Disease Control and Prevention funds state and local immunization infrastructure and vaccine distribution through the Immunization Cooperative Agreements program (CFDA 93.268), with the most recent grant awards disbursed as of September 30, 2025, and an active solicitation (CDC-RFA-IP-25-0007) due March 13, 2025.
The program funds establishment and maintenance of preventive health service programs delivering vaccines against measles, rubella, poliomyelitis, diphtheria, pertussis, tetanus, hepatitis B, and other vaccine-preventable diseases. Recent awards show funding for state immunization program operations including vaccine procurement and distribution, provider enrollment and compliance in the Vaccines for Children (VFC) program, immunization information system maintenance, vaccine confidence and education campaigns, outbreak response readiness, and targeted vaccination outreach to underserved and rural populations. Awards support activities across the full vaccination lifespan from perinatal hepatitis B prevention through adult immunization.
Portfolio activity shows 501 awards over more than two decades, with $6.86 billion in combined federal obligations. Awards per year have varied substantially, from 2 awards in 2022 to 19 in 2019 and 18 in 2025. The assistance-type distribution is predominantly Project Grants (88 percent, 440 awards) with a smaller share of Cooperative Agreements (12 percent, 60 awards). All funding concentration appears to rest with the Department of Health and Human Services Centers for Disease Control and Prevention across the portfolio.
Recent awards exemplify the program's scope: Colorado received $23.3 million for vaccine management, provider network expansion, and immunization information system certification; North Carolina received $33.1 million for Section 317 and VFC program operations including provider training and equity-focused vaccination efforts; Arizona received $18.7 million for vaccine access expansion through mobile units and tribal partnership strengthening; Missouri received $18.8 million for vaccine access, misinformation combat, and immunization infrastructure; and Houston received $10.4 million for VFC operations and perinatal hepatitis B prevention.
The current open solicitation (CDC-RFA-IP-25-0007, "Strengthening Vaccine-Preventable Disease Prevention and Response") requires Cooperative Agreement applications from U.S. states, political subdivisions, and other public entities (private individuals and private nonprofits are ineligible). The NOFO mandates application to all three components: Core funding, rapid small-scale outbreak response (funded), and rapid large-scale outbreak response (approved but unfunded). Projects run 1 to 5 years with up to five-year continuation possible on satisfactory progress. Initial budget periods typically run 12 months. The program requires no state match.
Objective and description
- Objective
To assist states and communities in establishing and maintaining preventive health service programs to immunize individuals against vaccine-preventable diseases (including measles, rubella, poliomyelitis, diphtheria, pertussis, tetanus, hepatitis B,
Eligibility
- Applicant eligibility
Any U.S. state, and in consultation with state health authorities, political subdivisions of states and other public entities and U.S. territories may apply; private individuals and private nonprofit agencies are not eligible for immunization grants.
- Beneficiary eligibility
Any U.S. state, political subdivision (as described above), and other public entities will benefit.
- Credentials and documentation
Any required credentials and/or documentation will be identified in the specific Notice of Funding Opportunity (NOFO) for this Assistance Listing.
- Uses of assistance
Cooperative Agreement funds may be used for costs associated with planning, organizing, and conducting immunization programs directed toward vaccine-preventable diseases and for the purchase of vaccine; and for the implementation of other program elements, such as assessment of the problem; surveillance and outbreak control; information and education; adequate notification of the risks and benefits of immunization; compliance with compulsory school immunization laws; vaccine storage, supply management, and delivery; citizen participation; and use of volunteers. Vaccine will be available "in lieu of cash" if requested by the applicants. Requests for personnel and other items "in lieu of cash" will also be considered. Vaccine purchased with Cooperative Agreement funds may be provided to private practitioners who agree not to charge for vaccine. Cooperative Agreement funds may be used to supplement (not substitute for) existing immunization services and operations provided by a state or locality.
- Length and time phasing of assistance
Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.
How to apply
- Criteria for selecting proposals
Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.
- Award procedure
After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.
- Deadlines
Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.
- Renewals
Project period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.
Grant opportunities
Show all 18
Grant awards
Latest 10 of 501 listed here. See the rest on GovTribe.
Top recipients by federal obligations
| Rank | Recipient | Federal obligations | Share |
|---|---|---|---|
| 1 | California Department Of Public Health | $1,573,417,600 | 23% |
| 2 | North Carolina Department Of Health & Human Services | $457,744,524 | 7% |
| 3 | Michigan Department Of Health And Human Services | $416,725,454 | 6% |
| 4 | New Jersey Department Of Health | $331,177,870 | 5% |
| 5 | Minnesota Department Of Health | $251,012,687 | 4% |
| 6 | Department Of State Health Services | $214,822,900 | 3% |
| 7 | Health Research, Inc. | $161,921,706 | 2% |
| 8 | Chicago Department Of Public Health | $159,096,493 | 2% |
| 9 | Florida Department Of Health | $152,651,201 | 2% |
| 10 | South Carolina Department Of Public Health | $150,339,142 | 2% |
10 of 101 recipients listed here. See the rest on GovTribe.
Federal obligations by fiscal year
| Fiscal year | Federal obligations |
|---|---|
| FY2026 | $198,527,676 |
| FY2025 | $395,490,303 |
| FY2024 | $298,008,845 |
| FY2023 | $864,012,872 |
| FY2022 | $647,227,056 |
| FY2021 | $7,178,401,038 |
| FY2020 | $1,389,136,062 |
| FY2019 | $361,631,847 |
| FY2018 | $329,002,402 |
| FY2017 | $379,583,290 |
| FY2016 | $247,574,580 |
| FY2015 | $303,636,151 |
| FY2014 | $311,097,393 |
| FY2013 | $306,724,336 |
| FY2012 | $302,967,141 |
| FY2011 | $290,876,485 |
| FY2010 | $287,141,913 |
| FY2009 | $289,825,024 |
| FY2008 | $233,101,265 |
| FY2007 | $37,555,914 |
| FY2006 | $96,753,941 |
| FY2005 | $1,458,632 |
| FY2004 | $5,493,402 |
| FY2003 | $3,677,025 |
| FY2002 | $170,008,552 |
Show all 25
Quick answers
What is Assistance Listing 93.268?
Assistance Listing 93.268 is Immunization Cooperative Agreements, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).
What is the CFDA number for Immunization Cooperative Agreements?
Its CFDA number is 93.268: Assistance Listing numbers were called CFDA numbers before 2018.
How much funding has Assistance Listing 93.268 awarded?
501 grant awards under 93.268 have obligated $6,863,656,310 in federal funds to 101 recipients.
Who receives the most funding from 93.268?
The recipients obligated the most under Immunization Cooperative Agreements are California Department Of Public Health ($1,573,417,600), North Carolina Department Of Health & Human Services ($457,744,524) and Michigan Department Of Health And Human Services ($416,725,454).
How much did 93.268 obligate in fiscal year 2025?
Grants under 93.268 obligated $395,490,303 in federal funds in fiscal year 2025.
Are there open grant opportunities under 93.268?
No opportunity listed under 93.268 is open now. The latest, Strengthening Vaccine-Preventable Disease Prevention and Response, was posted on August 7, 2024.
On GovTribe
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