Health Program for Toxic Substances and Disease Registry

Active

Assistance listing
93.161
Agency
Grant awards
242 $91,850,715 in federal obligations

Program facts

Assistance types
  • Project Grant
  • Cooperative Agreement
  • Block Grant
Treasury account
  • 75-8252-0-1-551
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Health and Human Services Centers for Disease Control and Prevention (CDC) through its Agency for Toxic Substances and Disease Registry (ATSDR) funds research, educational initiatives, and biomonitoring programs addressing exposure to toxic substances at spill and waste disposal sites and related public health impacts, under Assistance Listing 93.161, with the most recent grant award dated November 1, 2018.

Program activity has contracted significantly. The portfolio documents 242 awards spanning from 1991 to 2018, but award frequency has declined sharply: the program issued 18 awards in 2014, dropping to 5 in 2016, 2 in 2015, 4 in 2012, and only 1 in 2018. No grant opportunities have been posted since December 2021; the most recent opportunity, "Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)" (RFA-TS-22-001), closed April 22, 2022. The program shows minimal recent solicitation activity despite some forecast language in older postings.

Funded activities span two distinct research domains. Environmental health initiatives support biomonitoring of legacy and emerging contaminants in susceptible populations (particularly around Great Lakes sites), brownfields assessment and community remediation, pediatric environmental health specialty units providing clinical consultation on environmental exposures during reproduction and early development, and environmental education and workforce development. ALS research represents a significant recent focus, with multiple awards investigating risk factors including environmental exposures, gene-environment interactions, occupational and lifestyle determinants, and medical comorbidities among ALS patients. Representative awards include a $1.2 million project examining antecedent medical conditions and medications as ALS risk factors (awarded September 30, 2015), an $8.552 million prospective birth cohort study of uranium exposure in the Navajo Nation (September 1, 2010), and a $4.236 million cooperative agreement on environmental threats to reproductive and pediatric health (September 30, 2014).

Funding splits between two CDC sub-organizations: CDC proper issued 210 awards valued at $65.8 million, while ATSDR issued 32 awards valued at $26.1 million, for combined federal obligations of $91.9 million. Awards are predominantly Project Grants (86% of awards), with smaller shares of Block Grants (8%) and Cooperative Agreements (6%). Cooperative agreements, which dominate by dollar value in recent awards, support multi-year initiatives with periods of performance up to five years and non-competitive continuation potential subject to satisfactory progress.

Individual award magnitudes vary widely: recent project grants range from $55 thousand to $1.2 million, while cooperative agreements on biomonitoring and pediatric health typically exceeded $2 million. Eligible applicants include states, political subdivisions, federally recognized Indian tribal governments, public and private nonprofits, and universities. Budget periods run 12 months within a performance period of up to five years, with non-competitive continuation available pending satisfactory recipient progress and fund availability.

No grant opportunities are currently open. The most recent posted opportunity, CDC-RFA-TS-24-0005 (Pediatric Environmental Health Specialty Units), was posted August 17, 2023, with a due date of May 7, 2024, now closed. This solicitation sought cooperative agreements to maintain and strengthen the PEHSU network, providing evidence-based consultation on environmental exposures affecting reproductive and pediatric health across five regional units.

Objective and description

Objective

To work closely with State, local, and other Federal agencies to reduce or eliminate illness, disability, and death resulting from exposure of the public and workers to toxic substances at spill and waste disposal sites.

Description

To work closely with State, local, and other Federal agencies to reduce or eliminate illness, disability, and death resulting from exposure of the public and workers to toxic substances at spill and waste disposal sites.

Eligibility

Applicant eligibility

States or political subdivisions thereof, to include the District of Columbia, American Samoa, Guam, the Commonwealth of Puerto Rico, the Commonwealth of the Northern Mariana Islands, the Federated States of Micronesia, the Virgin Islands, the Federated States of Marshall Island, the Republic of Palau, National organizations, Federally-recognized Indian tribal governments, public and private non-profit universities and colleges.

Beneficiary eligibility

The general public and particularly individuals and families who reside around or near hazardous waste sites.

Uses of assistance

To strengthen State and local environmental health programs. Services may include: (1) Health assessments; (2) health effects studies; (3) exposure and disease registries; (4) technical assistance; (5) consultation; (6) dissemination of technical information; (7) provision of specialized services and assistance, including responses to public health emergencies; 8) training State and other health professionals in broad areas related to environmental health; and (9) research of chemical toxicity.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Time to approval or disapproval

Approximately 60 to 90 days.

Renewals

Cooperative agreement period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government."

Grant opportunities

Opportunity Status Posted Applications due
Pediatric Environmental Health Specialty Units (PEHSU) CDC-RFA-TS-24-0005 Closed
Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) RFA-TS-22-001 Closed
Pediatric Environmental Health Specialty Unit (PEHSU): Expansion Supplement CDC-RFA-TS19-19010301SUPP21 Closed
Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) RFA-TS-21-001 Closed
PEHSU COVID-19 Emergency Response Supplement CDC-RFA-TS19-19010201SUPP20 Closed
Pediatric Environmental Health Specialty Units (PEHSU) CDC-RFA-TS19-1901 Closed
Biomonitoring Legacy and Emerging Great Lakes Contaminants in Susceptible Great Lakes Populations CDC-RFA-TS16-1601 Closed
Continuing Prospective Birth Cohort Study Involving Environmental Uranium Exposure in the Navajo Nation RFA-TS-13-0010501SUPP15 Closed
Public Health Conference Support Program CDC-RFA-EH12-1201 Closed

Grant awards

Award Recipient Federal obligations Awarded
Analyze and evaluate potential risk factors for amyotrophic lateral sclerosis (ALS) R01TS000296 Dartmouth-Hitchcock Clinic $55,817
A population-based ohio ALS repository and a case-control study of ALS risk factors R01TS000245 Trustees Of Dartmouth College $632,549
Environmental risk factors and gene-environment interactions in ALS risk and progression R01TS000244 University Of Miami $724,475
ALS risk in latin americans- a population based case control comparative study with 3 european population based cohorts. R01TS000242 Trinity College Dublin $800,000
Biomonitoring legacy and emerging great lakes contaminants in susceptible great lakes populations U61TS000269 State Of Wisconsin Department Of Health Services $895,000
Biomonitoring legacy and emerging great lakes contaminants in susceptible great lakes populations NU61TS000269 State Of Wisconsin Department Of Health Services $358,671
Antecedent medical conditions and medications: associations with the risk and prognosis ALS R01TS000249 The Leland Stanford Junior University $1,200,000
Case-control studies nested in national ALS registry to evaluate environmental risks R01TS000243 The Trustees Of Columbia University In The City Of New York $1,142,115
Building partnership, expanding access & increasing awareness to reduce envir threats to reproductive & pediatric health U61TS000238 American College Of Medical Toxicology, Inc. $2,476,614
Meeting the environmental health needs of children U61TS000237 American Academy Of Pediatrics $2,202,485

Latest 10 of 242 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 44 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2024 $1,818,300
FY2023 $8,019,806
FY2022 $9,499,286
FY2021 $6,444,635
FY2020 $9,380,700
FY2019 $2,468,421
FY2018 $3,397,260
FY2017 $6,508,126
FY2016 $7,088,994
FY2015 $5,149,601
FY2014 $4,898,628
FY2013 $3,513,017
FY2012 $6,436,824
FY2011 $8,135,164
FY2010 $5,728,648
FY2009 $2,670,000
FY2008 $6,535,929
FY2007 $2,654,752
FY2006 $4,417,829
FY2005 $2,569,316
FY2004 $350,316
FY2003 $14,557,454
FY2002 $2,863,395
FY2001 $543,275
Show all 24

Quick answers

What is Assistance Listing 93.161?

Assistance Listing 93.161 is Health Program for Toxic Substances and Disease Registry, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Health Program for Toxic Substances and Disease Registry?

Its CFDA number is 93.161: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.161 awarded?

242 grant awards under 93.161 have obligated $91,850,715 in federal funds to 44 recipients.

Who receives the most funding from 93.161?

The recipients obligated the most under Health Program for Toxic Substances and Disease Registry are Association Of Occupational And Environmental Clinics ($11,160,491), University Of New Mexico ($8,552,760) and American College Of Medical Toxicology, Inc. ($7,299,936).

Are there open grant opportunities under 93.161?

No opportunity listed under 93.161 is open now. The latest, Pediatric Environmental Health Specialty Units (PEHSU), was posted on August 17, 2023.

On GovTribe

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