Project Grants and Cooperative Agreements for Tuberculosis Control Programs
Active
- Assistance listing
- 93.116
- Agency
-
Centers for Disease Control and Prevention
Department of Health and Human Services
- Grant awards
- 412 $2,127,103,812 in federal obligations
Program facts
- Assistance types
-
- Cooperative Agreement
- Project Grant
- Block Grant
- Treasury account
-
- 75-0950-0-1-550
- More information
Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.
About this program
The Centers for Disease Control and Prevention (CDC) funds tuberculosis prevention and control programs through state, territorial, and local public health agencies and selected national partners, with the most recent grant awards disbursed on January 1, 2025. CFDA 93.116 provides $2.13 billion in combined federal dollars obligated across 412 awards since 2002, predominantly through Cooperative Agreements (78 percent of awards) with a smaller mix of Project Grants (21 percent) and Block Grants (1 percent). Award activity spiked significantly in 2025 with 34 awards after minimal activity in 2022–2024, suggesting a major funding cycle reopened after a sustained pause.
The program funds state and local TB prevention and control programs to carry out core activities: identifying and treating persons with active TB disease; screening and treating contacts of TB patients for latent TB infection (LTBI) to prevent progression to active disease; maintaining TB surveillance systems and disease registries; conducting targeted testing of high-risk populations including immigrants, refugees, and persons with comorbidities such as HIV or diabetes; and strengthening public health laboratory capacity for TB diagnostic services. Recent awards reflect this scope. Vermont's TB Prevention Program received $561 thousand to enhance training and laboratory services statewide; Ohio's Department of Health received $4.03 million for case management, contact investigations, and medical consultation across local health departments; and Los Angeles County received $16.19 million to support case finding, directly observed therapy, contact investigation, and laboratory services in a high-burden jurisdiction. The program also funds specialized centers of excellence—the Curry International TB Center at UCSF received $8.81 million and the Southeastern National TB Center at the University of Florida received $12.15 million for training, education, and expert medical consultation to the TB healthcare workforce.
CDC dominates funding across all 412 awards with 100 percent of award count and federal dollars. Award magnitudes range widely: sub-million awards to low-incidence states; awards of $1–$4 million to mid-burden jurisdictions; and awards exceeding $6 million to high-burden states and major cities. Texas historically received the largest share at $196.2 million across the prior funding cycle (2020–2024); California received $134.9 million; and Washington State received $37.4 million.
Two grant opportunities are currently open or recent. CDC-RFA-PS-25-0003 (Tuberculosis Elimination and Laboratory Cooperative Agreement) posted February 15, 2024, with a final due date of October 4, 2024, and targets state and local governments to fund TB prevention, control, laboratory services, and human resource development over five years. CDC-RFA-PS-27-0053 (Strengthening Collaboration Between TB Control Programs and Affiliated Partners) posted September 25, 2026, seeking one recipient among nonprofits, state governments, tribal governments, and county governments to build partnerships and advance TB elimination through collaboration with TB programs, academia, community-based organizations, and other stakeholders.
Objective and description
- Objective
This program supports entities to conduct TB preventive health service programs to assist in carrying out tuberculosis (TB) control activities designed to prevent transmission of infection and disease. Financial assistance is provided to TB programs
- Description
This program supports entities to conduct TB preventive health service programs to assist in carrying out tuberculosis (TB) control activities designed to prevent transmission of infection and disease. Financial assistance is provided to TB programs to ensure that the program needs for core TB prevention and control activities, human resource development and public health laboratories are met. In addition, objectives include: finding all cases of active tuberculosis and ensuring completion of therapy; finding and screening persons who have had contact with TB patients, evaluating them for TB infection and disease, and ensuring completion of appropriate treatment; and conducting TB surveillance and TB public health laboratory activities that are essential to addressing these priorities. Each of these core activities (completion of therapy, contact investigation, TB surveillance, and TB laboratory activities) is essential to effective TB prevention and control.
Eligibility
- Applicant eligibility
Dependent upon the individual NOFO, eligibility may range from open competition, limited competition, single-source, domestic and/or international in accordance with the authorizing legislation.
- Beneficiary eligibility
Anyone/general public Beneficiary eligibility is the same as applicant eligibility.
- Uses of assistance
Funds may be used in the prevention or control of disease, disability and/or death by infectious diseases. Restrictions to funding are designated in the individual Notice of Funding Opportunity (NOFO) and, for those awarded, in the Notice of Award (NoA).
- Length and time phasing of assistance
Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.
How to apply
- Criteria for selecting proposals
Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity Announcements (NOFOs). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific and technical merit by objective or peer review, availability of funds, and relevance of program priorities and the priorities of CDC.
- Award procedure
After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.
- Deadlines
Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.
- Time to approval or disapproval
As specified in the individual NOFOs.
- Renewals
Cooperative agreement period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.
Grant opportunities
Grant awards
Latest 10 of 412 listed here. See the rest on GovTribe.
Top recipients by federal obligations
| Rank | Recipient | Federal obligations | Share |
|---|---|---|---|
| 1 | Department Of State Health Services | $260,668,807 | 12% |
| 2 | California Department Of Public Health | $230,498,562 | 11% |
| 3 | City Of New York | $154,090,975 | 7% |
| 4 | Florida Department Of Health | $146,040,704 | 7% |
| 5 | County Of LOS Angeles | $76,861,278 | 4% |
| 6 | New Jersey Department Of Health | $71,829,412 | 3% |
| 7 | Washington State Department Of Health | $49,229,325 | 2% |
| 8 | Massachusetts Department Of Public Health | $49,116,681 | 2% |
| 9 | City Of Houston | $46,731,985 | 2% |
| 10 | Department Of Public Health Illinois | $44,576,103 | 2% |
10 of 85 recipients listed here. See the rest on GovTribe.
Federal obligations by fiscal year
| Fiscal year | Federal obligations |
|---|---|
| FY2026 | $57,679,066 |
| FY2025 | $167,658,680 |
| FY2024 | $188,088,375 |
| FY2023 | $285,865,989 |
| FY2022 | $382,240,416 |
| FY2021 | $73,737,929 |
| FY2020 | $156,704,663 |
| FY2019 | $157,008,811 |
| FY2018 | $77,989,755 |
| FY2017 | $77,149,999 |
| FY2016 | $86,617,648 |
| FY2015 | $85,870,930 |
| FY2014 | $81,085,300 |
| FY2013 | $85,139,644 |
| FY2012 | $89,080,881 |
| FY2011 | $91,252,980 |
| FY2010 | $97,708,440 |
| FY2009 | $92,680,674 |
| FY2008 | $93,519,136 |
| FY2007 | $9,922,396 |
| FY2006 | $50,479,872 |
| FY2005 | $136,896 |
| FY2004 | $567,808 |
| FY2003 | $180,000 |
| FY2002 | $3,570,149 |
Show all 25
Quick answers
What is Assistance Listing 93.116?
Assistance Listing 93.116 is Project Grants and Cooperative Agreements for Tuberculosis Control Programs, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).
What is the CFDA number for Project Grants and Cooperative Agreements for Tuberculosis Control Programs?
Its CFDA number is 93.116: Assistance Listing numbers were called CFDA numbers before 2018.
How much funding has Assistance Listing 93.116 awarded?
412 grant awards under 93.116 have obligated $2,127,103,812 in federal funds to 85 recipients.
Who receives the most funding from 93.116?
The recipients obligated the most under Project Grants and Cooperative Agreements for Tuberculosis Control Programs are Department Of State Health Services ($260,668,807), California Department Of Public Health ($230,498,562) and City Of New York ($154,090,975).
How much did 93.116 obligate in fiscal year 2025?
Grants under 93.116 obligated $167,658,680 in federal funds in fiscal year 2025.
Are there open grant opportunities under 93.116?
1 listed opportunity under 93.116 is open or forecasted. The latest, Strengthening Collaboration Between Tuberculosis Control Programs and Affiliated Partners in the United States., was posted on September 25, 2026.
On GovTribe
See this program's full record
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