Predictive Science Academic Alliance Program

Active

Assistance listing
81.124
Agency
Grant awards
40 $310,803,807 in federal obligations

Program facts

Also known as
NNSA Predictive Science Academic Alliance Program
Assistance types
  • Cooperative Agreement
  • Project Grant
Treasury account
  • 89-0240-0-1-053
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Energy National Nuclear Security Administration (NNSA) funds university-based research in predictive science modeling, simulation methodologies, and artificial intelligence applications for large-scale computational problems, under Assistance Listing 81.124, with the most recent grant awards made in September 2025.

The program focuses on development and demonstration of high-performance computing technologies for verification, validation, and uncertainty quantification in large-scale simulations across discipline-specific and multidisciplinary research centers. Recent awards fund exascale simulation capabilities in domains including plasma turbulence modeling, multiphase combustion, material interfaces in extreme environments, radiation resilience of electronics, and AI-enhanced performance modeling for parallel computing systems. Work integrates machine learning and data science methodologies to advance predictive capabilities across physics-based and engineering applications. The program explicitly supports workforce development in computational science to build recruiting pipelines for NNSA laboratory missions.

Cooperative Agreements dominate the portfolio, representing 85 percent of 40 total awards since 2006, with Project Grants comprising the remaining 15 percent. The NNSA accounts for 25 awards totaling $207 million in federal obligations, while the broader Department of Energy funds 15 awards for $103.8 million, for a combined federal obligated total of $310.8 million. Recipients have provided an additional $38.4 million in non-federal cost-sharing, bringing combined total obligations to $349.2 million. Award activity shows nine awards in 2025 and nine in 2020, with intermediate years ranging from one to seven awards annually. Recent awards cluster in the $1.5 million to $5.4 million range per five-year cooperative agreement, though historical mega-awards reached $21 million to $22 million.

The PSAAP IV Notice of Funding Opportunity (DE-FOA-NA0003284) closed October 4, 2024, with nine awards estimated for approximately $105 million total program funding at an estimated ceiling of $3.5 million annually per award for up to five years. Eligible applicants are public or private institutions of higher education that award professional doctoral degrees. No additional open solicitations are present in the source.

Objective and description

Objective

(1) To focus on development and demonstration of modeling/simulation technologies and methodologies through the structure of Multidisciplinary Simulation Centers, Single-Disciplinary Centers, and Focus Investigatory Centers to solve open science and

Description

The Predictive Science Academic Alliance Program (PSAAP) engages with leading U.S. universities, focusing on the development and demonstration of technologies and methodologies to solve open science and engineering application problems. The research performed by the universities in this program is discipline-focused to further predictive science and enabled by effective use of high-performance computing. Predictive science is the aim of this program and is based on verification and validation and uncertainty quantification methodologies for large-scale simulations.

Eligibility

Applicant eligibility

Applicants (either prime or sub applicant) must be an institution of higher education in any state, federal district, or United States territory. Prime applicants must provide an educational program for which the institution awards a professional doctoral degree (e.g. Doctor of Philosophy or PhD).

Beneficiary eligibility

Only institutions of higher education in any state, federal district, or United States territory.

Uses of assistance

Financial support in whole or in part may be provided for such purposes as salaries, materials and supplies, equipment, travel, publication costs, training costs, and services required for conducting research, training, NNSA laboratory internships, and advanced technology projects or assessments. Funding is provided for applied research in the field of computational science in support of the NNSA Stockpile Stewardship program. Restrictions on use of funds depend on grant provisions. Funding is provided for the purpose of exploring a research idea that does not unnecessarily duplicate work already in progress or contemplated by DOE, is not already known to DOE, or has previously unrecognized merit.

Length and time phasing of assistance

The NNSA cooperative award assistance is available for total of 5 project-year time window, subject to approval of annual renewals. The annual funding should be expended within the allocated timeframe, with at least 10% allowed for carryover to the next fiscal year.

How to apply

Preapplication coordination

A Request for Information (RFI) for PSAAP III was initiated by the National Nuclear Security Administration (NNSA) Office of Advanced Simulation and Computing (ASC) and Institutional Research and Development Programs, Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL) and Sandia National Laboratories (SNL). An RFI was issued on June 29, 2018 with a deadline of August 3, 2018 for eligible institutions to submit a preliminary application in accordance with the guidelines stated in the PSAAP III RFI document. We released a Funding Opportunity Announcement in mid FY19. The selected PSAAP III Centers began during FY20. During FY24, the NNSA Academic Programs and Community Support, Office of Advanced Simulation and Computing (ASC) and Institutional Research and Development Programs (NA-114), Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL) and Sandia National Laboratories (SNL), initiated the next phase of its academic program, called Predictive Science Academic Alliance Program IV (PSAAP IV). PSAAP IV will add an additional focus, on the development and application of artificial intelligence (AI) and machine learning (ML) technologies to improve quantified predictive capabilities. The PSAAP IV Notice of Funding Opportunity was posted on May 22, 2024.

Application procedure

Applications should be submitted as specified in the notice of funding opportunity posted at http://www.grants.gov.

Criteria for selecting proposals

(1) Alignment with the areas of technical scope called forth in the call for application; (2) Scientific/technical merit of the project; (3) Expected impact on the proposed area of research activity; (4) Consistency with the objective of this academic alliances program to focus on advanced computational science investigations; (5) Qualifications of the Applicant's personnel and adequacy of proposed resources; (6) Feasibility of plans for carrying out the proposed research, considering such factors as: appropriateness of the technical method and approach, facility compatibility, other commitments, competition and timing; (7) Level of interaction with NNSA laboratory personnel and the potential to train students in scientific areas defined by the technical scope in order to build a long-term recruiting pool for the NNSA laboratory complex; (8) Leverage provided by cost sharing by applicant and with other funding sources.

Award procedure

Proposals will be screened for ASC programmatic relevance and then reviewed for scientific and technical merit by qualified individuals. Recommendations for award are made by the ASC office, Defense Programs, NNSA, and selected proposals will be forwarded to NNSA Partnership Acquisition Services, for grant development and award.

Time to approval or disapproval

See individual opportunity announcements at http://www.grants.gov for deadlines for each specific announcement.

Renewals

Applications for annual renewal are subject to review and acceptance by the NNSA Office of Advanced Simulation and Computing and Institutional Research & Development.

Grant opportunities

Opportunity Status Posted Applications due
Predictive science academic alliance program IV DE-FOA-NA0003284 Closed
NNSA Notice of Intent to Issue PSAAP IV Funding Opportunity Announcement Number DE-FOA-0003284 DE-FOA-0003299 Closed
Predictive Science Academic Alliance Program III (PSAAP III) DE-FOA-0002068 Closed
Predictive Science Academic Allance Program III DE-FOA-0001955 Closed

Grant awards

Award Recipient Federal obligations Awarded
Center for optimized modern parallel adaptive system software (COMPASS) will devise, utilize, and validate… DENA0004266 Massachusetts Institute Of Technology $2,858,543
To focus on development and demonstration of modeling/simulation technologies and methodologies through the structure… DENA0004269 Rector & Visitors Of The University Of Virginia $2,821,068
Through the center for optimized modern parallel adaptive system software (COMPASS), improve modern systems with… DENA0004267 University Of New Mexico $1,000,000
Psaap IV - high order plasma turbulence modeling for Z-pinch - focused investigatory center develop high-order… DENA0004265 Michigan State University $1,000,000
The vision for the predictive simulation center (PSC) is to revolutionize predictive science by unraveling and… DENA0004264 Regents Of The University Of Michigan $3,500,000
Exascale driven topology optimization of nonlinear metamaterial systems DER impact, enabled by ML accelerated… DENA0004262 University Of California, San Diego $1,000,000
The center for information geometric mechanics and optimization (CIGMO) will develop robust, high order-accurate… DENA0004261 Brown University $1,000,000
Center for advancing the radiation resilience of electronics (CARRE) - a psaap-IV predictive science center (PSC)… DENA0004268 Oregon State University $3,500,000
Multiscale modeling of multiphase combustion - a psaap IV predictive simulation center (PSC). In collaboration with the… DENA0004263 University Of Florida $2,134,252
The purpose of this cooperative agreement (CA) is to improve public safety and security by providing additional… DENA0004212 NYE County $0

Latest 10 of 40 listed here. See the rest on GovTribe.

Top recipients by federal obligations

Rank Recipient Federal obligations Share
1 The Leland Stanford Junior University $46,816,977 15%
2 University Of Illinois $37,880,856 12%
3 Purdue University $32,452,348 10%
4 University Of Utah $31,333,898 10%
5 University Of Texas At Austin $25,594,708 8%
6 Regents Of The University Of Michigan $23,998,437 8%
7 California Institute Of Technology $21,599,948 7%
8 The Regents Of The University Of Colorado $14,083,200 5%
9 University Of Florida $12,852,671 4%
10 Massachusetts Institute Of Technology $11,458,543 4%

10 of 22 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2025 $18,813,526
FY2024 $20,278,658
FY2023 $19,356,535
FY2022 $19,424,123
FY2021 $18,750,000
FY2020 $14,292,600
FY2019 $8,610,998
FY2018 $16,965,367
FY2017 $16,986,551
FY2016 $17,500,000
FY2015 $17,854,698
FY2014 $17,406,011
FY2013 $9,500,000
FY2012 $22,297,901
FY2011 $24,500,000
FY2010 $29,200,000
FY2009 $16,066,841
FY2008 $3,000,000
Show all 18

Quick answers

What is Assistance Listing 81.124?

Assistance Listing 81.124 is Predictive Science Academic Alliance Program, a federal grant program run by Department of Energy.

What is the CFDA number for Predictive Science Academic Alliance Program?

Its CFDA number is 81.124: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 81.124 awarded?

40 grant awards under 81.124 have obligated $310,803,807 in federal funds to 22 recipients.

Who receives the most funding from 81.124?

The recipients obligated the most under Predictive Science Academic Alliance Program are The Leland Stanford Junior University ($46,816,977), University Of Illinois ($37,880,856) and Purdue University ($32,452,348).

How much did 81.124 obligate in fiscal year 2025?

Grants under 81.124 obligated $18,813,526 in federal funds in fiscal year 2025.

Are there open grant opportunities under 81.124?

No opportunity listed under 81.124 is open now. The latest, Predictive science academic alliance program IV, was posted on May 22, 2024.

On GovTribe

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