The U.S. President's Emergency Plan for AIDS Relief Programs

Inactive

Assistance listing
19.029
Agency
Grant awards
1,636 $768,308,730 in federal obligations

Program facts

Assistance types
  • Cooperative Agreement
  • Project Grant

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of State Office of the Secretary of State administers the U.S. President's Emergency Plan for AIDS Relief Programs (CFDA 19.029), which funds HIV prevention, treatment, care, and support services across PEPFAR-supported countries, with the most recent award issued May 12, 2026.

The program funds concrete HIV service delivery and community engagement activities: youth-focused HIV prevention campaigns and education, community-led monitoring to improve quality of HIV care, pre-exposure prophylaxis (PrEP) access expansion among high-risk populations, treatment adherence support and tracking services, home-based care for people living with HIV, and interventions targeting key populations including sex workers, people who use drugs, and incarcerated individuals. Recent awards also include substantial procurement of HIV prevention medications and medical supplies through international sourcing platforms.

The portfolio is dominated by Project Grants (97 percent of 1,636 awards) with a small Cooperative Agreement component (3 percent). Across six distinct funding agencies, the Department of State as a principal entity obligated $448.8 million in three awards, while the Defense Health Agency contributed $188.2 million in one award. The Department of State Bureau of African Affairs issued the largest award count at 1,130 grants totaling $36.9 million; the Office of the Secretary of State distributed 480 awards worth $93.3 million. Combined federal dollars obligated total $768.3 million with minimal non-federal cost-share.

Recent large awards include a $260.5 million Project Grant to the Global Fund to Fight AIDS, Tuberculosis and Malaria for procurement of HIV prevention products (May 2026), a $150 million Cooperative Agreement for autonomous drone delivery networks across five African countries (October 2025), and a $38.3 million Project Grant for lenacapavir PrEP procurement (November 2025). Smaller awards reflect ground-level implementation: $20 thousand to $50 thousand grants fund youth HIV prevention education, stigma reduction, and community health literacy in districts across Mozambique, Tanzania, Zambia, and other PEPFAR countries.

Award volume has declined sharply: 226 awards in 2022 dropped to 10 in 2025 and 1 in 2026, signaling program transition or reallocation. An open Annual Program Statement (DFOP0017890), "Advancing Global Health," remains active with Statement of Interest due February 14, 2027, seeking unrestricted applicant types to advance bilateral health priorities under the America First Global Health Strategy. Earlier community-led monitoring and youth HIV prevention opportunities posted in 2024 (due dates between June and October 2024) have closed.

Objective and description

Objective

The Office of the U.S. Global AIDS Coordinator is responsible for coordinating and overseeing the U.S. global response to HIV/AIDS through the U.S. President's Plan for Emergency AIDS Relief (PEPFAR). The objective of this program is to provide suppo

Grant opportunities

Opportunity Status Posted Applications due
Advancing Global Health DFOP0017890 Open
PEPFAR Community Led Monitoring (CLM)-Zambia PCLM-2025 Closed
HIV prevention boys & men PEPFARWDHFY2401 Closed
HIV prevention for people with disabilities PEPFARWDHFY2402 Closed
PEPFAR Small Grants Program U.S. Embassy Yaounde AFYDE-YCIF-GR-PEPFAR-2024 Closed
PEPFAR Community-Led Monitoring (CLM) Grant 2025-PECO-GRANT01 Closed
PEPFAR Uganda Community Grants to Combat HIV/AIDS DOS-UGA-SMGCG-FY25 Closed
PEPFAR Small Grants: National level Coordination & Technical Support of Community-led Monitoring Program PSG-MBA-FY24-02 Closed
Community-Led Monitoring (CLM) PSG-MBA-FY24-01 Closed
PEPFAR Small Grants Virtual Spaces Intervention and Community-led Monitoring for Priority Populations in Nigeria DOS-NGA-ABV-PEPFAR-GR-24-001-042524 Closed
Pepfar media training and HIV anti-stigma programs DOS-ACC-NOFO-2024-01 Closed
PEPFAR DRC Community-Led Monitoring (CLM) Program AFPCO-24-02 Closed
PEPFAR DRC Community-Led Monitoring (CLM) Program AFPCO-24-01 Closed
PEPFAR Small Grants: National level Coordination & Technical Support of Community-led Monitoring Program PSG-MBA-FY22-02 Closed
Community-Led Monitoring (CLM) PSG-MBA-FY23-01 Closed
HIV-Quick Impact to local communities MAPUTO-PCO-FY24-01 Closed
Leadership Training for Adolescent Girls and Young Women MAPUTO-PCO-FY23-02 Closed
Pepfar media training and HIV anti-stigma programs DOS-ACC-NOFO-2023-1 Closed
PEPFAR Uganda Community Grants to Combat HIV/AIDS DOS-UGA-SMGCG-FY24 Closed
Tamkeen (an Arabic word meaning Empowerment) 72066823RFA00001 Closed
PEPFAR Zambia CLM Scorecard 2024 PZ-CLM-SCORECARD-2024 Closed
South Africa PEPFAR Community Grants 2023 2023-CGSA Closed
PEPFAR Small Grants Program, Capacity Building and Coordination for Community-Led Monitoring DOS-MSU-PEPFARCLMCB-FY24 Closed
PEPFAR Small Grants Program, Community-Led Monitoring 2024 DOS-MSU-PEPFARCLM-FY24 Closed
U.S. President's Emergency Plan for AIDS Relief (PEPFAR) Small Grants Program DOS-PSGP-FY23-001 Closed
U.S. President's Emergency Plan for AIDS Relief (PEPFAR) Small Grants Program DOS-APSGP-FY23-001 Past —
PEPFAR Zambia 2024 Small Grants NOFO PEPFAR-ZM-2024-SMALL-GRANTS Closed
Ambassador's Special Self-Help Program - PEPFAR Small Grants Fund 005-2022 Closed
PEPFAR Small Grants Program POL/ECON, U.S. Embassy Yaounde AFYDE-PSGCLM-GR-POLECON-2022 Closed
Community Led Monitoring -Routine Data Collection and Provider feedback at PEPFAR supported sites DOS-NBO-PCO-FY22-006 Closed
PEPFAR Community Led Monitoring (CLM)-Zambia PCLM-2023 Closed
PEPFAR Community Led Monitoring - Mozambique MAPUTO-PCO-FY23-01 Closed
Community -Led Monitoring PSG-MBA-FY22-01 Closed
PEPFAR Botswana Community Led-Monitoring (CLM) Program PEPFAR-GABORONE-AF-CLM-GR-22-23 Closed
PEPFAR Ethiopia Community-Led Monitoring (CLM) Activities 2022-PECO-002 Closed
U.S. Ambassador's President's Emergency Plan for AIDS Relief (PEPFAR) Small Grants Program Financial Year (FY) 2022 DOS-APSGP-FY22-001 Closed
PEPFAR Small Grants - Ambassador's Special Self-Help Program 0052021 Closed
Community Led Monitoring-Routine Data Collection and Provider feedback DOS-NBO-PCO-FY22-001 Closed
Community Led Monitoring-Routine Data Collection and Provider feedback DOS-NBO-PCO-FY22-002 Closed
Show 29 more

Latest 39 listed here. See the rest on GovTribe.

Grant awards

Award Recipient Federal obligations Awarded
Letter agreement between the united states of america acting through the department of state and the global fund to… SAQMMA26GR0022 The Global Fund To Fight Aids, Tuberculosis And Malaria (The Global Fund) $260,479,713
To fund the purchase of lenacapavir for prep through wambo.ORG for DOS / ghsd-financed beneficiaries in… SAQMIP26GR0017 The Global Fund To Fight Aids, Tuberculosis And Malaria (The Global Fund) $38,339,677
Enhance and expand recipient 's autonomous drone delivery network across up to five strategically selected african… SAQMIP26CA0007 Zipline International Inc. $150,000,000
Promote HIV/aids prevention among adolescents and young people aged 15-24 in vila DE gondola by creating youth clubs… SMZ50025GR0011 Associacao De Iniciativa Para O Desenvolvimento DA Comunidade- Aipdc $20,000
Enhance HIV literacy, foster a supportive and inclusive environment for discussions on safe SEX practices, and increase… SMZ50025GR0010 — $20,000
Enhance HIV knowledge and prevention among adolescents and young people while increasing their utilization of HIV… SMZ50025GR0008 Associacao Silver Lining Mocambique $20,000
To enhance awareness of safe sexual practices, reduce stigma and discrimination associated with HIV/aids, and promote… SMZ50025GR0007 Associacao Taremba Para Desenvolvimento Comunitario $20,000
To contribute to the prevention of HIV and aids among adolescents and young people, and promote services through… SMZ50025GR0006 Associacao Tchova Tchova Programas De Comunicacao Ttpc $20,000
To empower youth in moamba district with knowledge and resources to prevent HIV/aids, reduce stigma and discrimination… SMZ50025GR0005 — $20,000
To raise awareness, promote prevention, and encourage adherence to HIV/aids treatment among younger generations through… SMZ50025GR0004 — $20,000

Latest 10 of 1,636 listed here. See the rest on GovTribe.

Top recipients by federal obligations

8 of 516 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $546,467,904
FY2025 $50,124,370
FY2024 $44,403,443
FY2023 $7,466,051
FY2022 $7,114,269
FY2021 $7,528,464
FY2020 $4,926,320
FY2019 $2,931,101
FY2018 $4,356,957
FY2017 $8,133,068
FY2016 $84,037,714
FY2015 $437,211
FY2014 $381,859
Show all 13

Quick answers

What is Assistance Listing 19.029?

Assistance Listing 19.029 is The U.S. President's Emergency Plan for AIDS Relief Programs, a federal grant program run by Office of the Secretary of State (Headquarters Offices). It is inactive.

What is the CFDA number for The U.S. President's Emergency Plan for AIDS Relief Programs?

Its CFDA number is 19.029: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 19.029 awarded?

1,636 grant awards under 19.029 have obligated $768,308,730 in federal funds to 516 recipients.

Who receives the most funding from 19.029?

The recipients obligated the most under The U.S. President's Emergency Plan for AIDS Relief Programs are The Global Fund To Fight Aids, Tuberculosis And Malaria (The Global Fund) ($298,819,388), The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. ($188,156,400) and Zipline International Inc. ($150,000,000).

How much did 19.029 obligate in fiscal year 2025?

Grants under 19.029 obligated $50,124,370 in federal funds in fiscal year 2025.

Are there open grant opportunities under 19.029?

1 of the latest 39 opportunities under 19.029 is open or forecasted. The latest, Advancing Global Health, was posted on September 21, 2026.

On GovTribe

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