Biotechnology Risk Assessment Research

Active

Assistance listing
10.219
Agency
Grant awards
328 $100,110,129 in federal obligations

Program facts

Also known as
BRAG
Assistance type
  • Project Grant
Treasury accounts
  • 12-1500-0-1-352
  • 12-1003-0-1-271
  • 12-1502-0-1-352
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Agriculture National Institute of Food and Agriculture funds research under Biotechnology Risk Assessment Research Grants (BRAG, Assistance Listing 10.219) to generate science-based information supporting federal regulatory decisions on ecological effects of genetically engineered organisms, with the most recent grant award disbursed September 15, 2026.

The program has remained continuously active since 2001, with 328 cumulative awards totaling $100.1 million in federal obligations. Award cadence has held steady at 12–13 grants annually in recent years, though 2025 dropped to 6 awards and only 1 award appears in 2026 year-to-date, suggesting a potential slowdown or reporting lag. All awards in the portfolio are Project Grants, with no Cooperative Agreements or other assistance types present.

Funding is concentrated entirely within a single federal agency: the Department of Agriculture National Institute of Food and Agriculture has issued 328 awards (100 percent of total portfolio) across two internal funding lines reported in the portfolio data. No other federal agencies participate in BRAG.

Recent funded research spans environmental risk assessment of genetically engineered plants, microorganisms, and animals. Representative awards include: transplastomic potato lines engineered for terpene production, with assessment of ecological effects on herbivores, beneficial insects, soil microbes, and neighboring plants ($644,140, September 2026); RNA-based tools to track engineered microbial DNA transfer in soil communities ($649,760, September 2025); assessment of transgene escape via pollinator-mediated gene flow in canola with implications for herbicide-resistant traits ($368,418, September 2025); and characterization of unintended genome modifications from multiplex CRISPR editing in tomato ($649,999, September 2025). Award magnitudes cluster in the $640 thousand to $650 thousand range for research grants; several smaller grants of $20 thousand to $25 thousand support conferences and workshops on biotechnology regulation and risk assessment.

A grant opportunity with due date July 13, 2026 (USDA-NIFA-BRAP-011857) was posted June 18, 2026, seeking risk assessment research on ecological effects of genetically engineered organisms including plants, microorganisms, arthropods, fish, birds, livestock, and other animals. Eligibility is open to United States public or private research or educational institutions and organizations. The program has released opportunities annually; the most recent prior opportunity closed February 29, 2024. Consult the program's website at https://nifa.usda.gov/funding-opportunity/biotechnology-risk-assessment-research-grants-program-brag for current solicitation details, award timelines, and specific research priority areas, as RFAs provide the most current guidance on deadlines and substantive expectations.

Objective and description

Objective

The purpose of the BRAG program Assistance Listing 10.219, is to support the generation of new information that will assist Federal regulatory agencies [USDA's - Animal and Plant Health Inspection Service - Biotechnology Regulatory Services (APHIS-BR

Description

The purpose of the Biotechnology Risk Assessment Grants (BRAG) program is to support the generation of new information that will assist Federal regulatory agencies make science-based decisions about the effects of introducing genetically engineered organisms (GE) into the environment.

Eligibility

Applicant eligibility

Any public or private research or educational institution or organization.

Beneficiary eligibility

Any public or private research or educational institution or organization.

Uses of assistance

Grant funds must be used for allowable costs necessary to conduct approved research objectives. Funds may not be used for purposes other than those approved in the grant award documents.

Use restrictions

The use of grant funds to plan, acquire, or construct a building or facility is not allowed. Some grant funds may be used for minor alterations, renovations, or repairs deemed necessary to retrofit existing teaching or research spaces in order to carry out a funded project. However, requests to use grant funds for such purposes must demonstrate that the alterations, renovations, or repairs are incidental to the major purpose for which a grant is made. Indirect Cost (IDC) is not to exceed 30 percent of the recipient's Total Federal Funds Awarded (TFFA). 7 U.S.C. 3310 limits the recovery of IDC for the overall award to 30 percent of the TFFA under a research, education, or extension grant. Grant funds may not be used for endowment investing. Please refer to the NOFO, Part III.E and F - Program Description - Funding Restrictions for specific details.

Length and time phasing of assistance

In accordance with statutory time limits, project periods, including no-cost extensions of time, are not to exceed five (5) years. Further details are provided in the Award document Form NIFA-2009 and the NIFA General Terms and Conditions Grants and Cooperative Agreements.

How to apply

Preapplication coordination

All NOFOs are published on the NIFA website and Grants.gov. Applicants must complete the SAM.gov and Grants.gov registration process prior to applying. See the program NOFO for any program specific pre-application requirements.

Criteria for selecting proposals

Within guidelines established for the program as described in the Notice of Funding Opportunity (NOFO). The most current NOFOs are available via: https://nifa.usda.gov/funding-opportunity/biotechnology-risk-assessment-research-grants-program-brag

Award procedure

Applications are subjected to a system of peer and merit review in accordance with section 103 of the Agricultural Research, Extension and Education Reform Act of 1998 (7 U.S.C. 7613) by a panel of qualified scientists and other appropriate persons who are specialists in the field covered by the proposal. Within the limit of funds available for such purpose, the NIFA Authorized Departmental Officer (ADO) shall make grants to those responsible, eligible applicants whose applications are judged most meritorious under the procedures set forth in the NOFO. Reviewers will be selected based upon training and experience in relevant scientific, extension, or education fields, taking into account the following factors: (a) The level of relevant formal scientific, technical education, or extension experience of the individual, as well as the extent to which an individual is engaged in relevant research, education, or extension activities; (b) the need to include as reviewers experts from various areas of specialization within relevant scientific, education, or extension fields; (c) the need to include as reviewers other experts (e.g., producers, range or forest managers/operators, and consumers) who can assess relevance of the applications to targeted audiences and to program needs; (d) the need to include as reviewers experts from a variety of organizational types (e.g., colleges, universities, industry, state and Federal agencies, private profit and non-profit organizations) and geographic locations; (e) the need to maintain a balanced composition of reviewers with regard to minority and female representation and an equitable age distribution; and (f) the need to include reviewers who can judge the effective usefulness to producers and the general public of each application. See the program NOFO for specific details about evaluation criteria.

Time to approval or disapproval

From 30 to 60 days. Contact the National Program Leader (NPL), as indicated per CFDA Section # 152 - Headquarters Office regarding dates for specific deadlines, start and end dates, and range of approval/disapproval time. Information is also available via our website and may be obtained via the Grants.gov website. NIFA's respective links regarding general information are provided below: http://nifa.usda.gov/ http://www.grants.gov. SPECIAL NOTE: Please refer to the Competitive Request for Applications (RFAs) for further specific and pertinent details. The most current RFA is available via: https://nifa.usda.gov/funding-opportunity/biotechnology-risk-assessment-research-grants-program-brag RFAs are generally released annually. Hence, the RFAs provide the most current and accurate information available. Any specific instructions in the Competitive RFAs supersede the general information provided in the CFDA database.

Grant opportunities

Opportunity Status Posted Applications due
Biotechnology Risk Assessment Research Grants Program USDA-NIFA-BRAP-011857 Closed
Biotechnology Risk Assessment Research Grants Program USDA-NIFA-BRAP-010309 Closed
Biotechnology Risk Assessment Research Grants Program USDA-NIFA-BRAP-009504 Closed
Biotechnology Risk Assessment Research Grants Program USDA-NIFA-BRAP-008702 Closed
Biotechnology Risk Assessment Research Grants Program USDA-NIFA-BRAP-008032 Closed
Biotechnology Risk Assessment Grants Program USDA-NIFA-BRAP-007072 Closed
Biotechnology Risk Assessment Grants Program USDA-NIFA-BRAP-006674 Closed
Biotechnology Risk Assessment Grants Program USDA-NIFA-BRAP-006408 Closed
Biotechnology Risk Assessment Grants Program USDA-NIFA-BRAP-005435 Closed
Biotechnology Risk Assessment Grants Program USDA-NIFA-BRAP-004935 Closed
Biotechnology Risk Assessment Grants Program USDA-NIFA-BRAP-004069 Closed
Show all 11

Grant awards

Award Recipient Federal obligations Awarded
A recent study in plastid genetic engineering from the PDS' laboratories has greatly advanced chloroplast metabolic… 20263352246923 University Of Tennessee $644,140
Genetically engineered crops provide many benefits such as decreased pesticide use, increased yield, and increased… 20253352245312 Washington State University $368,418
The western corn rootworm, diabrotica virgifera virgifera, is the most serious insect pest of corn in the US corn belt… 20253352245311 Iowa State University Of Science And Technology $650,000
RNA interference (rnai) is a sequence-specific gene silencing mechanism and a promising novel mode of action for… 20253352245305 University Of Tennessee $643,910
The proposed research aligns with program area #5: other research topics designed to support the purposes of the brag… 20253352245304 University Of Maryland, College Park $649,999
Multiplex genome editing is a powerful tool for crop improvement, but IT also raises concerns about unintended… 20253352245288 University Of Connecticut $649,998
Microbes are increasingly being engineered to benefit society in areas such as agriculture and health. For example, new… 20253352245287 William Marsh Rice University $649,760
Awards issued prior to january 20, 2025, were funded under previous administrations and may not reflect the… 20243352243706 University Of Maryland, College Park $649,847
Awards issued prior to january 20, 2025, were funded under previous administrations and may not reflect the… 20243352243699 Board Of Regents Of The University Of Nebraska $649,929
Awards issued prior to january 20, 2025, were funded under previous administrations and may not reflect the… 20243352243698 University Of Florida $645,674

Latest 10 of 328 listed here. See the rest on GovTribe.

Top recipients by federal obligations

Rank Recipient Federal obligations Share
1 University Of Maryland, College Park $7,846,416 8%
2 North Carolina State University $7,190,733 7%
3 University Of Tennessee $4,491,129 4%
4 Iowa State University Of Science And Technology $4,118,053 4%
5 Oregon State University $4,085,925 4%
6 Board Of Regents Of The University Of Nebraska $3,326,056 3%
7 Regents Of The University Of Minnesota $3,059,786 3%
8 University Of Connecticut $2,934,644 3%
9 Clemson University $2,415,645 2%
10 Texas A&M Agrilife Research $2,391,837 2%

10 of 68 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $619,659
FY2025 $3,382,897
FY2024 $5,540,694
FY2023 $6,364,788
FY2022 $6,483,495
FY2021 $5,963,338
FY2020 $5,473,696
FY2019 $5,229,446
FY2018 $6,113,156
FY2017 $5,423,930
FY2016 $4,782,886
FY2015 $3,830,428
FY2014 $3,414,692
FY2013 $4,180,982
FY2012 $4,209,812
FY2011 $4,061,862
FY2010 $6,124,175
FY2009 $3,714,643
FY2008 $3,691,363
FY2007 $2,877,843
FY2006 $2,012,460
FY2005 $2,055,841
FY2004 $1,502,064
FY2003 $1,271,007
FY2002 $593,445
FY2001 $1,191,525
Show all 26

Quick answers

What is Assistance Listing 10.219?

Assistance Listing 10.219 is Biotechnology Risk Assessment Research, a federal grant program run by National Institute of Food and Agriculture (Department of Agriculture).

What is the CFDA number for Biotechnology Risk Assessment Research?

Its CFDA number is 10.219: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 10.219 awarded?

328 grant awards under 10.219 have obligated $100,110,129 in federal funds to 68 recipients.

Who receives the most funding from 10.219?

The recipients obligated the most under Biotechnology Risk Assessment Research are University Of Maryland, College Park ($7,846,416), North Carolina State University ($7,190,733) and University Of Tennessee ($4,491,129).

How much did 10.219 obligate in fiscal year 2025?

Grants under 10.219 obligated $3,382,897 in federal funds in fiscal year 2025.

Are there open grant opportunities under 10.219?

No opportunity listed under 10.219 is open now. The latest, Biotechnology Risk Assessment Research Grants Program, was posted on June 18, 2026.

On GovTribe

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