NBS Laboratory Information Management System - OIT

The Colorado Office of Information Technology is issuing RFI 2027000011 for a Laboratory Information Management System to support the state's Newborn Screening program, with responses due November 2, 2026. This is a Request for Information — a market research vehicle, not a binding procurement — and does not establish contract obligations or award timelines.

The LIMS must support comprehensive case management for abnormal newborn screens, including automated case creation, outcome tracking, specialist referral integration, and timestamped patient and family contact history. The system must provide hierarchical chain-of-custody tracking with electronic chain-of-custody logging, immutable possession records, and automated aliquot genealogy. Customer management capabilities must include submitter profiles for hospitals and birthing centers with automated ICD-10 and CPT code mapping and EDI integration compatible with state enterprise resource planning systems. Advanced data analysis is required, including a complex formula engine for user-defined calculations such as analyte ratios in mass spectrometry, multi-tiered cutoff logic based on gestational age and birth weight, automated result interpretation via decision-tree logic, and Ct value analysis. The system must incorporate Levey-Jennings and Westgard rules for quality control monitoring with real-time application to invalidate failed runs, population trend monitoring to detect instrument drift, and second-tier trigger logic for automated flagging.

The vendor must be a US-based entity with at least five years of SOC II Type II certification experience, provide a cloud-based application with 99.9% uptime guarantee, maintain a documented disaster recovery plan with annual reviews, and supply dedicated project management, implementation support including legacy data migration, and comprehensive testing and validation services. The contract period spans five years, with budgeting structured across development, implementation, and ongoing maintenance phases. Vendor responses should address system functionality, technical architecture, implementation timelines, and support capabilities to inform Colorado OIT's subsequent formal procurement strategy.