Biopharmaceutical Automated Fill Machine Isolator
Open State & local contract opportunity Posted
- Solicitation number
- 134-202627-001
- State
- North Carolina
- Responses due
Opportunity facts
- Jurisdiction
Opportunity details come from evp.nc.gov. Updated .
About this opportunity
Wilson Community College, operating the Biomanufacturing Education & Skills Training (BEST) Center of Eastern North Carolina, is requesting proposals for design, fabrication, delivery, installation, and commissioning of a biopharmaceutical automated fill machine isolator, with proposals due November 10, 2026 at 2:00 PM ET and questions due October 27, 2026.
The isolator will serve as a training device for manual aseptic processing and drug product manufacturing techniques within the BEST Center expansion, emphasizing educational value over high-throughput capability. The system must accommodate 2 ml and 25 ml injection vials with manual loading, automated filling at up to 40 units per minute with 1% accuracy, mechanical stopper insertion, and integrated containment with glove ports and rapid transfer ports. The awardee will execute design, fabrication, assembly, integration, and programming; Factory Acceptance Testing; delivery and installation on or after August 11, 2027; startup and commissioning; functional and acceptance testing; training; and delivery of required documentation through final project acceptance.
Pricing shall be submitted on a milestone basis across ten deliverable phases: Project Initiation & Project Management, Engineering and Design, Equipment and Materials Procurement, Fabrication/Assembly/Integration/Programming, FAT & PreShipment Inspection, Packaging/Freight/Transportation/Delivery, Installation/Startup/Commissioning, Acceptance Testing & Final Inspection, Training & Knowledge Transfer, and Final Documentation/Certificates/Project Closeout. All costs must be included in the proposal price; vendors may propose temporary import tariff surcharges as a separate line item subject to negotiation. The anticipated performance period is one year beginning after contract execution, with an anticipated award in December 2026.
Evaluation uses a Best Value methodology ranked by Technical Approach, Vendor References, Vendor Experience, Financial Statements, and Cost, in that order of importance. Vendors must be registered with the North Carolina Secretary of State and eVP, provide three customer references, demonstrate financial stability, and certify E-Verify compliance and fair employment practices. State responses to written questions are due November 3, 2026.
Opportunity text
The Biomanufacturing Education & Skills Training (BEST) Center of Eastern North Carolina, operated by Wilson Community College, is expanding its current design to include simulated cleanrooms that will be utilized for training in drug product manufacturing. To provide a capstone experience for trainees, the expansion will feature an automated fill machine housed in an isolator that simulates a controlled environment. Wilson Community College is seeking proposals to build and install a unit that meets the user requirements listed within. The design should facilitate advanced training on manual operations and aseptic techniques, with emphasis on educational value rather than high-throughput capability, operational flexibility, or additional premium features. The contract will include multiple phases, including project kickoff and design review; equipment design, fabrication, assembly, integration, and programming; Factory Acceptance Testing (FAT); delivery and installation; startup and commissioning; functional and acceptance testing; training; delivery of required documentation; and final project acceptance. Interested vendors should provide a written proposal that describes their solution.
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