9230-27-R-RFIN-00001

Jackson State University is issuing a Notice of Proposed Sole Source Purchase (SSP26-03, RFX 3150007041) for a five-year software license to the Schrodinger Small Molecule Drug Discovery Suite, with objections due by October 13, 2026. This is a sole-source procurement — Schrodinger, LLC (101 SW Main Street, Suite 1300, Portland, Oregon 97204) is the only vendor offering a fully integrated suite combining quantum chemistry, molecular dynamics, machine learning, and biologics modeling through proprietary modules including Glide, DeepAutoQSAR, and LigPrep.

The scope covers a comprehensive software platform for chemical systems investigation, including tools for target preparation, ligand preparation, workflow automation, and virtual modeling. The license uses a floating model enabling shared use across the institution by faculty, staff, and students. The estimated total cost is $65,318.25 over the five-year term, reflecting academic and volume-based discounts tied to the license commitment and including first-year server hosting within the hosted, shared license model. Jackson State University's procurement department determined this price fair and reasonable following direct negotiation with the vendor. Objections to the sole-source designation must be submitted in writing to Kimberly R. Harris, Director of Procurement Services, at kimberly.r.harris@jsums.edu with the subject line "Sole Source Objection" and must include detailed explanation and supporting documentation that another vendor can provide the commodity.