9230-26-R-RFIN-00003

Jackson State University is pursuing a sole source procurement for the Schrodinger Small Molecule Drug Discovery Suite software under RFX 3150006510, with a solicitation released on September 9, 2025, and proposals due by September 22, 2025. The procurement specifically targets a comprehensive software platform designed for investigating chemical systems, which includes advanced tools for target preparation, ligand preparation, workflow automation, and virtual modeling. The software will be available for use by faculty, staff, and students, supporting the university's Center's mission to advance drug discovery through high-performance computational resources. The procurement is being conducted as a sole source purchase due to the unique and unparalleled capabilities of the Schrodinger software, which has been determined to have no comparable alternatives in the market. Potential vendors must recognize that Jackson State University has conducted extensive market research confirming Schrodinger, LLC as the sole manufacturer of this molecular modeling software with an integrated, validated framework. Any objections to the sole source procurement must be submitted in writing to Kimberly R. Harris, Director of Procurement Services, with appropriate supporting documentation.

The procurement appears to be open to all vendors, with no specific set-aside designations or restrictions mentioned in the documentation. Schrodinger, LLC is the incumbent and sole vendor for this specific software suite, having negotiated directly with Jackson State University to secure academic and volume-based discounts. The total estimated cost of the software is $44,460.00, which covers a three-year license term with a floating license model. The university has strategically evaluated the software's capabilities and determined it meets their computational research requirements. No specific integration requirements with existing infrastructure are explicitly outlined in the documentation. The procurement represents a targeted acquisition of specialized scientific software with a clear focus on supporting advanced molecular modeling and drug discovery research capabilities at the university.