Strategic Prevention Framework - Partnerships for Success for Communities/Tribes

The Substance Abuse and Mental Health Services Administration (SAMHSA) is accepting applications for the Strategic Prevention Framework - Partnerships for Success for Communities/Tribes program through July 15, 2026, with a hard cap of 60 complete, high-quality applications reviewed; once this threshold is met, the submission portal closes and no further applications are considered.

Eligible applicants include state governments, local governments, federally recognized Indian tribal governments, institutions of higher education, nonprofit organizations, and community-based service providers. The program supports the development and delivery of community-based substance use prevention services that strengthen protective factors, reduce risk factors, build resilience, and promote well-being. Grantees must expand and strengthen the capacity of prevention providers serving communities and tribes to implement evidence-based, evidence-informed, and community-defined evidence-based prevention strategies.

Awards are made through the Center for Substance Abuse Prevention Projects of Regional and National Significance (CFDA 93.492). SAMHSA issues awards directly to applicants following merit review, program analysis, and concurrence by the CSAP National Advisory Council. Recipients must retain records for three years; retention extends beyond three years if final audits remain incomplete or findings are unresolved. The source does not specify award amount, award floor, expected number of awards beyond the 60-application intake limit, period of performance, or place of performance.