Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
Closed Posted
- Opportunity number
- PAR-24-306
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Up to $499,000
Opportunity facts
- Assistance listings
-
- 93.393 Cancer Cause and Prevention Research
- 93.394 Cancer Detection and Diagnosis Research
- 93.395 Cancer Treatment Research
- 93.396 Cancer Biology Research
- Funding instrument
- Grant
- Categories
-
- Education
- Health
- Eligible applicants
-
- 501(c)(3) Nonprofits
- For Profit Organizations
- Special District Governments
- Higher Education Inst. (Private)
- Public or Indian Housing Auth.
- City/Township Governments
- County Governments
- Tribal Organizations (Not Federally Recognized)
- Tribal Governments (Federally Recognized)
- Independent School Districts
- State Governments
- Higher Education Inst. (Public)
- Other
- Small Businesses
- Non-501(c)(3) Nonprofits
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Cancer Institute (NCI) is seeking applications for the "Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)" federal grant opportunity. The NCI is inviting projects that aim to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. The key objectives are to demonstrate that mammalian models are robust representations of human biology, appropriate for testing clinically important questions, and provide reliable information for patient benefit. Eligible applicants include nonprofits, for-profit organizations, higher education institutions, and state/local governments. The grant opportunity is part of the NCI's Cancer Detection and Diagnosis Research, Cancer Treatment Research, Cancer Cause and Prevention Research, and Cancer Biology Research federal grant programs.
Recent Federal Grant Awards under similar NCI programs have ranged from approximately $200,000 to over $1.6 million in total costs, with typical project periods spanning 2-5 years. The research activities are expected to be conducted at the recipient organizations' facilities across the United States, with some opportunities allowing for international collaboration, particularly for clinical trial components.
Synopsis
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for projects to expand, improve, or transform the utility of mammalian cancer and tumor models for translational research. With this NOFO, the NCI intends to encourage submission of projects devoted to demonstrating that mammalian models or their derivatives used for translational research are robust representations of human biology, are appropriate to test questions of clinical importance, and provide reliable information for patients' benefit. These practical goals contrast with the goals of many mechanistic, NCI-supported R01 projects that employ mammals, or develop and use mammalian cancer models, transplantation tumor models, or models derived from mammalian or human tissues or cells for hypothesis-testing, non-clinical research. Among many other possible endeavors, applicants in response to this FOA could propose demonstrations of how to overcome translational deficiencies of mammalian oncology models, define new uses of mammalian models or their genetics for unexplored translational challenges, advance standard practices for use of translational models, test approaches to validate and credential models, or challenge current practices for how models are used translationally
Files
| File | Type | Posted |
|---|---|---|
| PAR-24-306-Full-Announcement.html | HTML file |
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