Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
Open Posted
- Opportunity number
- PAR-25-068
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Categories
-
- Food and Nutrition
- Health
- Eligible applicants
-
- Non-501(c)(3) Nonprofits
- Special District Governments
- 501(c)(3) Nonprofits
- Tribal Organizations (Not Federally Recognized)
- Higher Education Inst. (Private)
- Public or Indian Housing Auth.
- Other
- City/Township Governments
- County Governments
- Small Businesses
- State Governments
- Independent School Districts
- Tribal Governments (Federally Recognized)
- For Profit Organizations
- Higher Education Inst. (Public)
- Points of contact
-
- NIH OER Webmaster grantsinfo@nih.gov
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases is soliciting applications for innovative basic and translational pilot research projects aligned with NIH HIV/AIDS research priorities, with an application due date of November 16, 2027. This opportunity is expired as of September 15, 2026, in accordance with NOT-OD-26-029, and is no longer accepting new applications.
Eligible applicants include higher education institutions (public and private), for-profit organizations, small businesses, non-profit organizations (including non-501(c)(3) nonprofits), state and local governments, tribal governments (federally recognized and not federally recognized), special district governments, public or Indian housing authorities, independent school districts, and other entities. Eligible Agencies of the Federal Government, faith-based or community-based organizations, historically Black colleges and universities, Hispanic-serving institutions, Alaska Native and Native Hawaiian serving institutions, AANAPISIs, tribally controlled colleges and universities, regional organizations, and U.S. territories or possessions may also apply. Non-domestic entities and non-domestic components of U.S. organizations are not eligible; foreign components as defined in the NIH Grants Policy Statement are allowed.
The program prioritizes research addressing pathophysiological mechanisms contributing to HIV comorbidities, coinfections, and complications affecting organs, tissues, and processes within NIDDK's mission; biological mechanisms underlying HIV reservoirs in NIDDK-relevant tissues for developing strategies for long-term viral suppression or eradication; and health-impeding social determinants of health affecting these conditions. Clinical trials are not allowed under this R21 mechanism. The funding falls under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Synopsis
2 versions
Update #2 · Latest ·
This Notice of Funding Opportunity (NOFO) invites applications for innovative basic and translational pilot research projects within the mission of the NIDDK that are aligned with NIH HIV/AIDS research priorities. These priorities were most recently outlined by the NIH Office of AIDS Research (OAR) in NOT-20-018, UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding, scientific priorities. Potential topics could address multiple overarching priorities. These include elucidation of unique pathophysiological mechanisms contributing to HIV comorbidities, coinfections, and complications (CCCs) affecting organs, tissues, and processes within the mission of the NIDDK. Likewise, interrogations into biological mechanisms underlying HIV reservoirs in NIDDK-relevant tissues are important for developing strategies for long-term viral suppression or eradication. Finally, health-impeding social determinants of health may affect CCCs or viral reservoirs within NIDDK's mission through multiple pathways.
Update #1 ·
This Notice of Funding Opportunity (NOFO) invites applications for innovative basic and translational pilot research projects within the mission of the NIDDK that are aligned with NIH HIV/AIDS research priorities. These priorities were most recently outlined by the NIH Office of AIDS Research (OAR) in NOT-20-018, UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding, scientific priorities. Potential topics could address multiple overarching priorities. These include elucidation of unique pathophysiological mechanisms contributing to HIV comorbidities, coinfections, and complications (CCCs) affecting organs, tissues, and processes within the mission of the NIDDK. Likewise, interrogations into biological mechanisms underlying HIV reservoirs in NIDDK-relevant tissues are important for developing strategies for long-term viral suppression or eradication. Finally, health-impeding social determinants of health may affect CCCs or viral reservoirs within NIDDK's mission through multiple pathways.
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Files
| File | Type | Posted |
|---|---|---|
| PAR-25-068-Full-Announcement.html | HTML file | |
| PKG00289951.pdf |
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