PAR-25-068-Full-Announcement.html

This Notice of Funding Opportunity (NOFO) PAR-25-068 is issued by the Department of Health and Human Services National Institutes of Health for pilot studies examining biological, behavioral, and social mechanisms contributing to HIV pathogenesis within NIDDK's mission. The opportunity is available to a wide range of applicants including higher education institutions, for-profit organizations, small businesses, government entities, tribal organizations, and non-profit organizations.

The funding focuses on research projects aligned with NIH HIV/AIDS research priorities, specifically investigating pathophysiological mechanisms of HIV comorbidities, coinfections, and complications affecting NIDDK-relevant organs and tissues. Key research areas include studying biological mechanisms of HIV reservoirs and examining social determinants of health affecting these conditions. The grant falls under the federal grant program 93.847 for Diabetes, Digestive, and Kidney Diseases Extramural Research. The funding instrument is a grant, with research activities categorized under Health and Food and Nutrition. No clinical trials are allowed under this R21 mechanism.