NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

Forecasted Federal grant Posted

Opportunity number
RFA-DA-28-002
Agency
Applications expected due
Award size
Up to $375,000

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Higher Education Inst. (Public)
  • Non-501(c)(3) Nonprofits
  • Independent School Districts
  • Higher Education Inst. (Private)
  • City/Township Governments
  • Tribal Governments (Federally Recognized)
  • Small Businesses
  • For Profit Organizations
  • County Governments
  • 501(c)(3) Nonprofits
  • Special District Governments
  • Tribal Organizations (Not Federally Recognized)
  • Public or Indian Housing Auth.
  • Other
  • State Governments
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute on Drug Abuse (NIDA) is soliciting applications for the Avenir Program, which supports fundamental mechanistic research in addiction science among early-stage investigators (ESIs), with a forecast status and no stated application deadline.

The program is open to a broad range of applicant types, including higher education institutions (public and private), 501(c)(3) and non-501(c)(3) nonprofits, small businesses, for-profit organizations, state and local governments, tribal governments (both federally and non-federally recognized), faith-based and community-based organizations, and eligible federal agencies. No cost share or matching requirement is stated.

NIDA is expanding the historically early-career-focused Avenir Program to support bold mechanistic research across genetic, epigenetic, molecular, cellular, circuit, chemical, pharmacological, behavioral, and cognitive processes relevant to Substance Use Disorders. Applications proposing novel, unconventional, or interdisciplinary wet-lab and data science approaches are encouraged. The program targets ESIs who may lack preliminary data for R01 applications but demonstrate high-impact research potential and capacity to lead future fundamental mechanistic addiction science.

Award ceiling, floor, and anticipated number of awards are not disclosed in the forecast. Period of performance, place of performance, and specific evaluation weighting are not detailed in this initial announcement. The opportunity is assigned CFDA 93.279 (Drug Use and Addiction Research Programs) under the broader NIH Drug Use and Addiction Research Programs portfolio, which emphasizes basic, clinical, translational, and implementation research in substance use prevention, diagnosis, and treatment.

Forecast synopsis

Avenir, the French word for "future," reflects NIDA's commitment to developing the next generation of leaders in addiction science. Since 2015, the Avenir Program has supported exceptionally creative early stage investigators (ESIs) in launching innovative research programs. NIDA is now expanding this program to support bold mechanistic research across a broader range of addiction science, including genetic, epigenetic, molecular, cellular, circuit, chemical, pharmacological, behavioral, and cognitive processes relevant to Substance Use Disorders (SUDs).

This initiative is intended to catalyze high-risk, high-reward research and attract outstanding new investigators, including those from outside the addiction field. Applications proposing novel, unconventional, or interdisciplinary wet-lab and/or data science approaches to advance understanding of the mechanisms underlying SUDs are encouraged. The Avenir Program is designed for ESIs who may lack the preliminary data needed for an R01 application but propose high-impact research and show strong potential to become future leaders in fundamental mechanistic addiction science.

Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

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