New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
Open Posted
- Opportunity number
- PAR-25-272
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
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- 93.396 Cancer Biology Research
- 93.865 Child Health and Human Development Extramural Research
- 93.866 Aging Research
- Funding instrument
- Grant
- Categories
-
- Health
- Education
- Income Security and Social Services
- Eligible applicants
-
- Special District Governments
- County Governments
- Tribal Organizations (Not Federally Recognized)
- Other
- For Profit Organizations
- Independent School Districts
- Small Businesses
- Non-501(c)(3) Nonprofits
- 501(c)(3) Nonprofits
- Tribal Governments (Federally Recognized)
- State Governments
- City/Township Governments
- Higher Education Inst. (Public)
- Higher Education Inst. (Private)
- Public or Indian Housing Auth.
- Points of contact
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- NIH OER Webmaster grantsinfo@nih.gov
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health is soliciting applications for exploratory research developing novel or innovative approaches to measure brain activity, connectivity, genomics, or other aspects of neurodevelopment across the age spectrum, with an application due date of May 7, 2027. This R21 mechanism is designated high-risk, high-reward and intended for multidisciplinary investigators whose work either lacks preliminary data or requires additional preliminary work.
Eligible applicants include higher education institutions (public and private), nonprofits (501(c)(3) and non-501(c)(3)), for-profit organizations, small businesses, state and local governments, tribal governments (federally recognized and other), special district governments, independent school districts, housing authorities, and other entities. Additionally eligible are Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, HBCUs, Asian American Native American Pacific Islander Serving Institutions, Tribally Controlled Colleges and Universities, faith-based or community-based organizations, regional organizations, non-domestic entities, and U.S. territories or possessions.
Research may focus on healthy human participants of any age, specific clinical groups such as those with cognitive, motor, or affective regulation challenges, and animal research. Studies can examine longitudinal neuroanatomical or functional changes at any level, including genetics and genomics, single cells, connectomics, neural population activity patterns, and other domains. The overarching goal is to extend understanding of brain development and aging, including neurodevelopmental origins of later health and disease, by improving repeated measures across longer lifespan epochs to better predict outcomes at later ages.
This opportunity operates under three CFDA programs: Child Health and Human Development Extramural Research (93.865), Cancer Biology Research (93.396), and Aging Research (93.866). Evaluation criteria include significance of the proposed research, approach, innovation, investigator qualifications, and research environment. Applications receive dual scientific review by non-NIH scientists and secondary review by the relevant national advisory council.
Synopsis
The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing exploratory, highly novel new approaches, or innovative applications of existing approaches to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease, by improving repeated measures across longer epochs of the lifespan to better predict outcomes at later ages. . Research can include healthy human participants of any age, specific clinical groups such those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function. The studies can focus on longitudinal neuroanatomical or functional changes at any level, including genetics/genomics, single cells, connectomics, neural population activity patterns, and others. This funding opportunity is intended to encourage technological and conceptual innovation through this high risk, high reward funding mechanism to develop highly innovative ideas that either lack preliminary data or need additional preliminary data
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Files
| File | Type | Posted |
|---|---|---|
| PAR-25-272-Full-Announcement.html | HTML file | |
| PKG00288973.pdf |
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