Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
Closed Posted
- Opportunity number
- PAR-24-078
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
-
- 93.310 Trans-NIH Research Support
- 93.351 Research Infrastructure Programs
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Higher Education Inst. (Public)
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
This limited competition notice of funding opportunity announces continuing support for specific pathogen-free macaque colonies previously funded under PAR-21-089 and PAR-18-669. The National Institutes of Health seeks applicants from higher education institutions to sustain pedigree macaque colonies that are free of certain viruses. The macaques will support HIV/AIDS research and are genetically characterized for major histocompatibility complex class I types known to impact immune responses to simian immunodeficiency virus and human immunodeficiency virus. Applications will be evaluated based on the ability to maintain appropriate SPF macaques for HIV/AIDS research while avoiding risks to animal care personnel, with a deadline of January 25, 2024.
Anticipated award amounts and periods of performance will be determined in accordance with the applicable Public Health Service grant policies. Research is expected to be performed at the facilities of the applicant organization.
Synopsis
The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.
Files
| File | Type | Posted |
|---|---|---|
| PAR-24-078-Full-Announcement.html | HTML file |
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