Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
Closed Posted
- Opportunity number
- PAR-24-129
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
-
- 93.351 Research Infrastructure Programs
- 93.310 Trans-NIH Research Support
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Higher Education Inst. (Public)
- Points of contact
-
- NIH OER Webmaster grantsinfo@nih.gov
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health is no longer accepting applications under this cooperative agreement funding specific pathogen-free macaque colonies to support HIV/AIDS research; this opportunity expired effective immediately per NOT-OD-26-029, superseding the original September 25, 2026 application deadline.
Eligibility was limited to public higher education institutions that previously received funding under PAR-21-089 and PAR-18-669. Non-domestic entities and foreign components of U.S. organizations were not eligible to apply. The instrument was a cooperative agreement, with award values ranging from approximately $22,000 to $4,000,000 and project periods of one to five years.
The program provided continuing support for breeding colonies essential to sustain specific pathogen-free macaques for HIV/AIDS research. Pedigree SPF macaques are free of certain viruses that may confound HIV/AIDS investigation results or present personnel risk. The macaques are genetically characterized for major histocompatibility complex class I types, as MHC class I genotypes substantially influence macaque immune responses to Simian Immunodeficiency Virus and human immune responses to HIV.
The opportunity operated under two CFDA numbers: Trans-NIH Research Support (93.310) and Research Infrastructure Programs (93.351). Applications were reviewed for scientific and technical merit by a scientific review group and for program relevance by a national advisory council or board. The review cycle typically required four to nine months. Grantees were subject to audit requirements under OMB 2 CFR 200 as implemented by 45 CFR 75, with financial and programmatic records retained for three years from the date the annual Federal Financial Report was submitted to NIH.
Synopsis
The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.
Eligibility
Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. see NOFO for eligibility details
Files
| File | Type | Posted |
|---|---|---|
| PKG00289338.pdf | ||
| PKG00284512.pdf |
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