Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
Open Posted
- Opportunity number
- PAR-25-225
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- Higher Education Inst. (Public)
- Small Businesses
- 501(c)(3) Nonprofits
- Non-501(c)(3) Nonprofits
- Independent School Districts
- Tribal Organizations (Not Federally Recognized)
- State Governments
- City/Township Governments
- Special District Governments
- Public or Indian Housing Auth.
- Tribal Governments (Federally Recognized)
- County Governments
- Other
- Higher Education Inst. (Private)
- For Profit Organizations
- Points of contact
-
- NIH OER Webmaster grantsinfo@nih.gov
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health is soliciting applications for the Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies, with an application due date of October 20, 2027. Clinical trials are not permitted under this funding opportunity.
Eligible applicants include higher education institutions (public and private), small businesses, 501(c)(3) and non-501(c)(3) nonprofits, independent school districts, tribal organizations, state and local governments, public or Indian housing authorities, for-profit organizations, and other entities. Additionally eligible are Alaska Native and Native Hawaiian serving institutions, Asian American Native American Pacific Islander serving institutions, faith-based or community-based organizations, Hispanic-serving institutions, historically Black colleges and universities, Indian or Native American tribal governments (whether or not federally recognized), non-domestic entities, regional organizations, tribally controlled colleges and universities, and U.S. territories or possessions.
The program funds pharmacodynamic, pharmacokinetic, and in vivo efficacy studies designed to demonstrate that proposed therapeutic agents possess sufficient biological activity to warrant further development for neurological or neuromuscular disorders falling under the NINDS mission. Eligible therapeutic agents include small molecules, biologics, and biotechnology-derived products. The funded work aims to advance projects to meet entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.
This opportunity is reissued as PAR-21-122 and operates under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). Awards are made as grants. Review occurs through technical panels and the National Advisory Neurological Disorders and Stroke Council, with evaluation based on scientific merit, experimental design adequacy, investigator competency, facilities and resources, budget necessity, and relevance to program objectives.
Synopsis
Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders that fall under the NINDS mission. Therapeutic agents include small molecules, biologics or biotechnology-derived products. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Files
| File | Type | Posted |
|---|---|---|
| PAR-25-225-Full-Announcement.html | HTML file | |
| PKG00288452.pdf |
On GovTribe
Work this opportunity
- Track it in your pipeline
- Find teaming partners
- Similar grant opportunities
- Ask GovTribe AI about this opportunity