PAR-25-225-Full-Announcement.html

This document is a Notice of Funding Opportunity (NOFO) for the Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed) grant program.

The NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agents have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders under the NINDS mission. Eligible applicants include for-profit organizations, non-profits, small businesses, higher education institutions, governments, and tribal organizations. The grant program is funded by the Department of Health and Human Services National Institutes of Health under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853). The goal is to advance projects to meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.