Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)
Forecasted Federal grant Posted
- Opportunity number
- RFA-TS-27-018
- Agency
-
Centers for Disease Control and Prevention
Department of Health and Human Services
- Applications expected due
- Award size
- Up to $500,000
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- County Governments
- Independent School Districts
- Unrestricted
- Tribal Governments (Federally Recognized)
- Higher Education Inst. (Public)
- Non-501(c)(3) Nonprofits
- City/Township Governments
- State Governments
- Tribal Organizations (Not Federally Recognized)
- Other
- Special District Governments
- Public or Indian Housing Auth.
- Higher Education Inst. (Private)
- 501(c)(3) Nonprofits
- Points of contact
-
- Candis Hunter ncipc_erpo@cdc.gov (770) 488-1347
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Centers for Disease Control and Prevention (CDC/ATSDR) is forecasting a cooperative agreement to fund research into risk factors for amyotrophic lateral sclerosis (ALS) under Assistance Listing 93.061, Innovations in Applied Public Health Research, with the forecast posted July 8, 2026. The listed applicant types are county governments, independent school districts, unrestricted, federally recognized tribal governments, public and private higher education institutions, non-501(c)(3) and 501(c)(3) nonprofits, city and township governments, state governments, tribal organizations (not federally recognized), special district governments, public or Indian housing authorities, and other. Additional eligibility information will be included in the NOFO. The source states no cost share or matching requirement and no award floor, ceiling, or expected award count for this opportunity.
Research falls under four funding options. Option A supports research with strong existing evidence, such as studies of known environmental or genetic risk factors. Option B supports new and exploratory research, including risk factors with little existing evidence or innovative methods. Option C examines ALS risk in affected populations, such as military veterans. Option D analyzes biological samples from the Guamanian ALS cluster. Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infectious agents and exposures are encouraged.
The source gives no place of performance. Program-level descriptions cite typical research awards of $150,000 to approximately $2 million and project periods of 1 to 5 years with 12-month initial budget periods, while the program description cites project periods of up to 3 years. Review applies scientific and technical merit by objective or peer review, availability of funds, and relevance to program and CDC priorities, with no weighting stated.
The program's portfolio shows 236 awards totaling $163.8 million since 2002, with no awards after September 2020. Recent ALS metabolomic and biomarker awards under the program were $2.06 million and $1.96 million.
Forecast synopsis
CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.
Eligibility
Additional Eligibility Information to be included in the NOFO.
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