Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)
Forecasted Federal grant Posted
- Opportunity number
- RFA-TS-27-018
- Agency
-
Centers for Disease Control and Prevention
Department of Health and Human Services
- Applications expected due
- Award size
- Up to $500,000
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Non-501(c)(3) Nonprofits
- Independent School Districts
- Public or Indian Housing Auth.
- Tribal Governments (Federally Recognized)
- Unrestricted
- State Governments
- 501(c)(3) Nonprofits
- Higher Education Inst. (Public)
- Special District Governments
- Higher Education Inst. (Private)
- City/Township Governments
- Tribal Organizations (Not Federally Recognized)
- County Governments
- Other
- Points of contact
-
- Dr. Candis M. Hunter ncipc_erpo@cdc.gov (770) 488-1347
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Centers for Disease Control and Prevention is soliciting cooperative agreement applications to identify and evaluate potential risk factors for amyotrophic lateral sclerosis, with a hard deadline to be included in the Notice of Funding Opportunity.
Eligible applicants include public and private nonprofits, for-profit organizations, state and local governments, tribal governments (federally and non-federally recognized), tribal organizations, independent school districts, public or Indian housing authorities, special district governments, county governments, city/township governments, higher education institutions (public and private), and other entity types.
The program funds four distinct options: Option A supports research with strong existing evidence on known environmental or genetic risk factors or investigations linking risk factors to ALS diagnosis and treatment; Option B funds new and exploratory research using innovative methods on ALS risk factors with limited existing evidence; Option C focuses on understanding ALS risk in affected populations such as military veterans; Option D analyzes biological samples from the Guamanian ALS cluster to investigate disease mechanisms, environmental factors, exposure routes, genetic studies, biomarkers, and potential mitigation therapeutics, diagnostics, or prevention strategies. Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infectious agents and exposures are encouraged.
The program operates under CFDA 93.061, Innovations in Applied Public Health Research. Project periods extend up to five years with non-competitive continuation eligibility contingent on satisfactory progress and fund availability. Initial awards cover the first budget period (typically 12 months). The forecast indicates $4.5 million in estimated total program funding, though individual award ceilings are not specified in this posting. Applications undergo peer review for scientific and technical merit, with selection based on relevance to program and CDC priorities and fund availability.
Forecast synopsis
CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encouraged. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.
Eligibility
Additional Eligibility Information to be included in the NOFO.
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