Hepatitis C Elimination Initiative Pilot

Closed Posted

Opportunity number
TI-25-005
Agency
Applications due
Award size
Up to $7,500,000

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Other
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The Substance Abuse and Mental Health Services Administration (SAMHSA) is seeking pilot program grants to develop a Hepatitis C Elimination Initiative focusing on preventing, testing, treating, and curing Hepatitis C in individuals with substance use disorder and/or severe mental illness, particularly in communities experiencing homelessness. The primary objective is to create a proof-of-concept program that identifies effective strategies for patient identification, treatment completion, and reinfection reduction. Applicants will be evaluated based on merit and peer review criteria, with applications scored and typically funded in order of their ranking. The grant falls under the Substance Abuse and Mental Health Services Projects of Regional and National Significance program (CFDA 93.243), which supports comprehensive behavioral health initiatives. The application deadline is August 1, 2025, and applicants must comply with federal administrative requirements, including using the SF-424 form and adhering to HHS grants policy guidelines.

While specific award amounts are not explicitly stated, similar grants under this program have historically ranged from $120,000 to $3,200,000, with project periods typically spanning 3-5 years. Eligible applicants include public organizations such as state and local government units, domestic nonprofit organizations, community-based organizations, universities, colleges, hospitals, and tribal educational agencies. The performance locations are expected to be nationwide, with a focus on community health centers, academic institutions, and various healthcare settings that can effectively implement interventions for populations with substance use disorders and mental health challenges. The initiative aims to develop nationally significant intervention models that can be potentially scaled or replicated in other communities experiencing similar health challenges.

Synopsis

The purpose of this proof-of-concept program is to leverage existing health care institutions' capacity to prevent, test for, treat, and cure Hepatitis C (HCV) in individuals with substance use disorder (SUD) and/or severe mental illness (SMI), particularly in communities severely affected by homelessness and to gain insights on effective ways to identify patients, complete treatment and reduce reinfection.

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