Emergency Department Alternatives to Opioids Program

Closed Posted

Opportunity number
TI-26-018
Agency
Applications due
Award size
Up to $500,000

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Other
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The Substance Abuse and Mental Health Services Administration (SAMHSA) is soliciting applications for the Emergency Department Alternatives to Opioids Program with an application due date of July 27, 2026. The program funds organizations to establish and implement practices that develop alternatives to pharmacological opioid interventions for pain, reduce harmful consequences of opioid use in hospitals and emergency departments, and promote safer pain treatment while reducing risk of future opioid misuse and overdose.

Eligible applicants are categorized as "Other," reflecting the program's focus on organizations beyond traditional state agencies and tribes. The program operates under CFDA 93.788, the Opioid STR grant program administered by SAMHSA.

The core program objective requires establishing evidence-based alternatives to opioid pain management in acute care settings. Activities encompass implementing non-pharmacological and pharmacological alternatives, reducing opioid-related harms, and evaluating intervention effectiveness to identify sustainable practices for safer pain treatment protocols.

Grantees must maintain complete records on fund disposition and retain all grant-related records for three years. Awards are administered as project grants with performance occurring at applicant organization locations. Applications are reviewed on merit, undergo program analysis, and require Center for Substance Abuse Treatment National Advisory Council concurrence before award.

The source does not specify award ceiling, award floor, expected number of awards, period of performance duration, or cost share requirements.

Synopsis

The purpose of the program is to establish and implement practices which will help your organization develop alternatives to pharmacological opioid interventions, reduce the potential harmful consequences of opioid use for pain care in hospitals and emergency departments, thereby promoting safer pain treatment and reducing the risk of future opioid misuse and possible opioid overdose.

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