Discovery of the Genetic Basis of Childhood Cancers and of Structural Birth Defects: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

Closed Posted

Opportunity number
PAR-23-035
Agency
Applications due
Award size
Not on record

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Non-501(c)(3) Nonprofits
  • Other
  • Independent School Districts
  • Higher Education Inst. (Private)
  • Higher Education Inst. (Public)
  • Public or Indian Housing Auth.
  • Small Businesses
  • Special District Governments
  • For Profit Organizations
  • County Governments
  • Tribal Organizations (Not Federally Recognized)
  • City/Township Governments
  • Tribal Governments (Federally Recognized)
  • 501(c)(3) Nonprofits
  • State Governments
Full announcement

Opportunity details come from Grants.gov. Updated .

Synopsis

As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program-supported sequencing center. Applicants are encouraged to propose sequencing of existing pediatric cancer or structural birth defect cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of structural birth defects, to study the molecular basis of the associations between birth defects and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts of underrepresented racial and ethnic groups or to increase racial and ethnic representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the research community.

Files

File Type Posted
PAR-23-035-Full-Announcement.html HTML file

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