Countering Biological Weapons Threats

Closed Posted

Opportunity number
DFOP0017244
Agency
Applications due
Award size
$250,000 to $5,000,000

Opportunity facts

Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Other
Eligible applicants
Not on record
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The Department of State's Bureau of International Security and Nonproliferation (ISN/CTR) is soliciting cooperative agreement proposals through its Biosecurity Engagement Program (BEP) to counter biological weapons threats. The program seeks to prevent U.S. adversaries from developing biological weapons, protect U.S. biotechnologies and intellectual property, and bolster U.S. leadership in global biotechnology markets. Eligible applicants include U.S. and foreign for-profit organizations, non-profit organizations, higher education institutions, and public international organizations. Proposals will be evaluated based on their ability to demonstrate an institutional record of successful projects and potential to achieve the NOFO's objectives of preventing biological weapons development and promoting U.S. laboratory security standards. The application deadline is July 30, 2025, at 11:59 PM EDT, with an anticipated project start date of January 1, 2026.

The funding opportunity will award approximately 10 grants totaling $15 million, with individual awards ranging from $250,000 to $5 million. The program targets partner countries across Africa, East Asia Pacific, Europe, Near East, South and Central Asia, and the Western Hemisphere, with a focus on specific countries including Argentina, Brazil, Japan, Kenya, and India. Project performance periods are expected to range from 12 to 24 months, with a preference for 15-month timelines. The grants are part of the Global Threat Reduction program (CFDA Number 19.033) and will be administered through cooperative agreements or inter-agency agreements, emphasizing engagement with biological laboratories, universities, government entities, and private industry to strengthen international biosecurity practices.

Synopsis

ISN/CTR's Biosecurity Engagement Program (BEP) advances the Trump Administration's Executive Order (E.O.) on Improving the Safety and Security of Biological Research, which pledges to "balance the prevention of catastrophic consequences with maintaining readiness against biological threats and driving global leadership in biotechnology, biological countermeasures, biosecurity, and health research". In alignment with this E.O., BEP engages partner countries to prevent U.S. adversaries from developing or using biological weapons (BW) against Americans. BEP also protects U.S. biotechnologies, sensitive data, and intellectual property (IP), and bolsters U.S. leadership of global biotechnology markets through private sector engagement to outcompete China, and promotes partner countries' adoption of U.S. laboratory security, safety, and cybersecurity standards. To successfully achieve this mission, BEP partners include biological and biotechnology laboratories, bio- and data repositories, universities, science and technology organizations or academies, foreign government organizations and entities, biosafety associations or similar professional associations, and private industry. The expertise and tools acquired through BEP engagements are critical to enable our partners to counter the predatory and exploitative efforts of U.S. adversaries that threaten U.S. national and economic security.

Files

File Type Posted
CTR NOFO Q&A - Posted 18 July 2025.docx DOCX document
CTR NOFO Q&A - Final posted 28 July.pdf PDF
CTR NOFO Q&A - 6 June.docx DOCX document
CTR NOFO Q&A - Posted 20 June 2025.docx DOCX document
CTR NOFO Q&A - For teams to added to - posted 27 June.docx DOCX document
CTR NOFO Q&A - posted 11 July.docx DOCX document
CTR NOFO Q&A - 13 June 2025.docx DOCX document
CTR NOFO Q&A - posted 8 July.docx DOCX document
CTR NOFO Q&A - posted 25 July.docx DOCX document
Monitoring Indicator Table Sample.xlsx XLSX spreadsheet
Monitoring Indicator Table Sample.xlsx XLSX spreadsheet
FY25 CTR Project Narrative Template 250708.docx DOCX document
FY25 CTR Project Narrative Template 250401.docx DOCX document
FY25 CTR Consolidated Project List.xlsx XLSX spreadsheet
FY 2025 Budget Template 241004.xlsx XLSX spreadsheet
BEP FY25 NOFO DFOP0017244 - 30 May 2025.docx DOCX document
BEP FY25 NOFO DFOP0017244 - 6 June 2025.docx DOCX document
Show all 17

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