Clinical Data Ecosystem for Genomics (CDEG)

Past Federal grant forecast Posted

Opportunity number
FOR-HG-26-005
Agency
Applications expected due
Award size
Not on record

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • Independent School Districts
  • Tribal Organizations (Not Federally Recognized)
  • Public or Indian Housing Auth.
  • Tribal Governments (Federally Recognized)
  • Higher Education Inst. (Private)
  • County Governments
  • 501(c)(3) Nonprofits
  • Higher Education Inst. (Public)
  • For Profit Organizations
  • Small Businesses
  • State Governments
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health National Human Genome Research Institute (NHGRI) intends to solicit applications through a cooperative agreement to establish a Clinical Data Ecosystem for Genomics (CDEG) network that identifies, shares, and improves approaches for clinical integration and structured data sharing of genome sequencing data and interpretation among labs, healthcare providers, and patients; no application due date has been announced, as this is a forecast intended to allow applicants time to develop collaborations. Applications are not currently being accepted.

Eligible applicants include independent school districts, tribal organizations (not federally recognized), public or Indian housing authorities, federally recognized tribal governments, private and public higher education institutions, county and state governments, 501(c)(3) nonprofits, for-profit organizations, and small businesses.

The network will establish a pilot ecosystem demonstrating best practices for sharing genomic structured data across healthcare settings including primary care; create standardized application programming interfaces to support data access; develop open-source clinical software applications and databases utilizing these APIs; demonstrate the pilot ecosystem's ability to overcome barriers to accessing patient genomic data as patients move across healthcare systems; and refine practices into implementation resources for broader adoption. Collaborative investigations combining expertise in computational genomics and data science, electronic health records, genomic data standards, cloud and database development, health information exchange, and clinical genomics implementation are encouraged.

The funding instrument is listed under U01 activity code (cooperative agreement). Awards fall under Assistance Listing 93.172 (Human Genome Research). A Notice of Funding Opportunity will be published with specific award amounts, period of performance, cost share requirements, and evaluation criteria at that time.

Forecast synopsis

The National Human Genome Research Institute (NHGRI) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research reduce barriers to a Clinical Data Ecosystem for Genomics (CDEG) by establishing a network to identify, share, and improve approaches for clinical integration and sharing of genome sequencing data and their interpretation as structured data among labs, health care providers, and patients. Specifically, the Network will: 1) establish a pilot ecosystem that demonstrates best practices for the sharing of genomic structured data (GSD) across different health care settings, including primary care; 2) create standardized application programming interfaces (APIs) to support access to such data; 3) develop open-source clinical software applications and databases that utilize these APIs; 4) demonstrate the ability of the pilot ecosystem to overcome barriers to accessing patient genomic data as patients travel across healthcare systems; and 5) refine and develop these practices into implementation resources for broader sharing and adoption. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. Investigators with expertise and insights into this area of genomic medicine and implementation science are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in computational genomics and data science, electronic health records (EHR), genomic data standards, cloud and database development, health information exchange, and implementing genomics in clinical care will be encouraged and these investigators should also begin considering applying for this application.

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