Centers of Excellence to Enhance Disease Detection in Newborns
Closed Posted
- Opportunity number
- CDC-RFA-EH-24-0044
- Agency
-
Centers for Disease Control and Prevention
Department of Health and Human Services
- Applications due
- Award size
- $750,000 to $1,000,000
Opportunity facts
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Unrestricted
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Centers for Disease Control and Prevention (CDC) is seeking applicants for a 4-year cooperative agreement to establish a Newborn Screening (NBS) Center of Excellence. The Center will work to develop infrastructure to implement advanced technologies, such as next-generation sequencing and high-resolution mass spectrometry, to expand NBS system capacity, optimize screening performance, and incorporate bioinformatics to analyze complex data. Eligible applicants are unrestricted, excluding for-profit organizations. Key objectives include piloting methods to enhance NBS practices, collaborating with the NBS community, and partnering with CDC experts on data harmonization. Proposals are due by June 4, 2024, with an expected award date around July 30, 2024 and a project start date of September 30, 2024.
The total available funding for this opportunity is up to $4 million over the 4-year project period, with up to $1 million per budget period. One award is expected to be made. The place of performance will be the recipient's public health laboratory facilities, with expected collaboration and data sharing across partner jurisdictions.
Synopsis
The use of dried blood spots to screen newborns for serious diseases has had a significant impact in saving lives and improving developmental outcomes since 1963. The adoption of new technologies into public health laboratory workflows has made it possible to screen newborns for an increasing number of diseases. Today, advanced technologies, such as Next Generation Whole Genome Sequencing and High-Resolution Mass Spectrometry, can enhance key aspects of newborn screening (NBS) practice, including early detection of current and newly added diseases. However, incorporating these advanced and complex technologies into NBS often requires substantial resources. To enhance NBS practice, CDC announces a new NOFO for a public health laboratory to establish a NBS Center of Excellence that will 1) develop infrastructure to implement existing, advanced technologies to expand NBS system capacity, 2) use advanced technologies as second and third tier testing platforms to optimize screening performance, and 3) incorporate bio-informatics to analyze complex biochemical and molecular data. Over the four-year project, the recipient will pilot methods to enhance NBS practices in public health laboratories, collaborate and share findings with the NBS community, and partner with CDC subject-matter experts on data harmonization and modernization efforts. This project will better position NBS programs to adapt to advanced technologies and meet increasing demands within NBS.
Files
| File | Type | Posted |
|---|---|---|
| Center of Excellence NOFO FAQ_rev 5_23_24.pdf | ||
| CDC-RFA-EH24-0044 FAQ.pdf | ||
| Foa_Content_of_CDC-RFA-EH-24-0044.pdf |
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