Centers of Excellence in Genomic Science (CEGS)

Past Federal grant forecast Posted

Opportunity number
PAR-26-036
Agency
Applications expected due
Award size
Not on record

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • 501(c)(3) Nonprofits
  • Higher Education Inst. (Public)
  • Higher Education Inst. (Private)
  • Non-501(c)(3) Nonprofits
  • Tribal Organizations (Not Federally Recognized)
  • City/Township Governments
  • Special District Governments
  • Independent School Districts
  • State Governments
  • County Governments
  • Tribal Governments (Federally Recognized)
  • Other
  • Small Businesses
  • Public or Indian Housing Auth.
  • For Profit Organizations
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health National Human Genome Research Institute (NHGRI) is forecasting a Notice of Funding Opportunity for the Centers of Excellence in Genomic Science (CEGS) program to solicit applications for cooperative agreements that fund interdisciplinary research teams addressing challenging biomedical questions from a genomics perspective. The program seeks highly innovative novel concepts, methods, approaches, tools, and technologies that achieve transformative advances unlikely to result from standard R01s or comparable projects over the same timeframe. Each center must address a critical issue in genomic science, genomic medicine, computational genomics, or an area cutting across more than one of these domains.

Eligible applicants include 501(c)(3) and non-501(c)(3) nonprofits, public and private higher education institutions, tribal governments (federally and non-federally recognized), city and county governments, state governments, special district governments, independent school districts, small businesses, for-profit organizations, public or Indian housing authorities, eligible federal agencies, U.S. territories or possessions, faith-based or community-based organizations, regional organizations, and non-domestic entities.

CEGS must balance high scientific risk with high payoff potential and develop outstanding management strategies. Required activities include dissemination of developed methods and tools to the broader research community and broadening the pool of researchers able to work in or use genomics. A February 2024 program evaluation identified strengths in the high-risk funding mechanism and technology development linked to biological questions, with suggestions for widening focus and increasing outreach opportunities to be addressed in this renewal. The program operates under Assistance Listing 93.172 (Human Genome Research). Applications undergo scientific merit review and advisory council consideration before award.

Forecast synopsis

The National Human Genome Research Institute (NHGRI) intends to promote an initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the Centers of Excellence in Genomic Science (CEGS) program. The purpose of the CEGS program is to bring together interdisciplinary teams of investigators to form tightly focused, well-integrated projects that address challenging biomedical questions from a genomics perspective. CEGS are expected to develop highly innovative novel concepts, methods, approaches, tools, and technologies to address these questions and achieve a transformative advance not likely developed by standard R01s or other projects over the same timeframe. Importantly, each CEGS will address a critical issue in genomic science, genomic medicine, computational genomics, or an issue that cuts across more than one of these areas. Given these goals, each center is required to have outstanding scientific plans and management strategies that balance a high level of risk with the potential for high payoff. Additional goals of the CEGS program include broadening the pool of researchers able to work in or use genomics, and dissemination of CEGS developed methods and tools to the broader research community.

In February 2024 a mixed-methods evaluation (see evaluation report) was completed to assess the outcomes of this flagship NHGRI program. The evaluation highlighted several strengths such as the high-risk, high-reward nature of the CEGS funding mechanism, a focus on technology development linked to biological questions, and the funding of several breakthrough resources and approaches that have surpassed genomics to stimulate many research areas. Suggestions for improvements, such as widening the focus and increasing outreach opportunities, will be addressed in this renewal.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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