Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

Open Posted

Opportunity number
PAR-25-444
Agency
Applications due
Award size
Not on record

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Tribal Governments (Federally Recognized)
  • For Profit Organizations
  • Other
  • County Governments
  • Tribal Organizations (Not Federally Recognized)
  • Special District Governments
  • 501(c)(3) Nonprofits
  • Small Businesses
  • Higher Education Inst. (Public)
  • Independent School Districts
  • State Governments
  • City/Township Governments
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Private)

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Cancer Institute seeks applications for Cancer Center Support Grants (P30 CCSGs) to support NCI-Designated Cancer Centers, with applications due September 25, 2028. New applicants must demonstrate a funding base of at least $10 million in annual direct costs of NIH cancer-focused funding (Clinical or Comprehensive Cancer Centers) or $6 million (Basic Cancer Centers); renewal applicants must have at least $10 million in peer-reviewed cancer-related funding. Foreign organizations and non-domestic components of U.S. organizations are not eligible.

Eligible applicants include higher education institutions (public and private), nonprofits (501(c)(3) and non-501(c)(3)), for-profit organizations, state and local governments, tribal governments and organizations, and independent school districts. Consortia of institutions may apply, with the combined funding base of all previously NCI peer-reviewed approved partners counting toward the minimum threshold.

The program supports three center types: Comprehensive Cancer Centers (demonstrating depth and breadth across basic laboratory, clinical, and prevention/population research with substantial transdisciplinary work); Clinical Cancer Centers (focused on laboratory, clinical, and prevention/population research); and Basic Cancer Centers (focused on basic laboratory research). Annual award ceilings are $1.2 million for Basic, $1.4 million for Clinical, and $1.5 million for Comprehensive Cancer Centers in direct costs. The period of performance is five years with potential extension to seven years.

Funded activities include scientific leadership salaries, shared research resources, administrative costs, planning and evaluation, developmental funds for new investigator recruitment, and community outreach. Centers must demonstrate an adequate base of established high-quality research programs, evidence of interdisciplinary coordination, appropriate facilities, qualified leadership, and institutional commitment.

Assistance Listing 93.397.

Synopsis

This Notice of Funding Opportunity (NOFO) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-Designated Cancer Centers. CCSGs support three types of Cancer Centers: 1) Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas; and 2) Clinical Cancer Centers, which are primarily focused on basic laboratory; clinical; and prevention, cancer control, and population-based research; or some combination of these areas, and 3) Basic Cancer Centers, which focus on basic laboratory research. The purpose of all types of NCI-Designated Cancer Centers is to capitalize on all institutional cancer research capabilities, integrating meritorious research into a single transdisciplinary research enterprise across all institutional boundaries. Cancer Centers supported through this NOFO are expected to serve as major sources of discovery of the nature of cancer and of development of more effective approaches to prevention, diagnosis, and therapy; to contribute significantly to the development of Shared Resources that support research; to collaborate and coordinate their research efforts with other NCI-funded programs and investigators; and to disseminate research findings for the benefit of the community.

Eligibility

Specific to this NOFO:For New (Type 1) applications, an applicant institution must have a funding base of $10,000,000 (Clinical Cancer Centers) or $6,000,000 (Basic Cancer Centers) in annual direct costs of NIH funding that is cancer-focused, as defined by the Research Condition and Disease Categorization (RCDC) system. Please contact the NCI Office of Cancer Centers (https://cancercenters.cancer.gov/) for assistance in determining the RCDC funding base.For Renewal (Type 2) applications, an applicant institution must have a funding base of at least $10,000,000 in annual direct costs of peer-reviewed, cancer-related funding. If the Cancer Center is an approved consortium of institutions, the funding base of the Center will be the sum of the funding bases of all participating institutions. However, funding (and other data) awarded to consortium partners may be included only if the partner has been previously evaluated in CCSG peer-review and approved by NCI.Example of NCI peer-reviewed mechanisms that may be included for determining eligibility to apply for a CCSG: DP1, DP2, R00, R01, R03, R15, R18, R21, R24, R25, R33, R35, R37, R41, R42, R50, R55, R56, P01, P20, P30s other than the CCSG, P50, SC1, SC2, U01, U10, U19, U24, U54, U56, UH2, UH3, UG3, T32, K and F series awards and N01s (excluding SEER and other N01s funding materials, services, or research resources). Cancer-relevant research funded by these mechanisms from other NIH Institutes may also be counted towards the minimum, as do cancer-relevant grants and contracts from the peer-reviewed funding sources listed in: https://cancercenters.cancer.gov/sites/default/files/PeerReviewFundingOrganizations.pdfNOTE: New (Type 1) applications cannot request evaluation for comprehensiveness status.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Files

File Type Posted
PAR-25-444-Revised-Full-Announcement.html HTML file
PKG00291700.pdf PDF
PAR-25-444-Full-Announcement.html HTML file

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