Botanical Dietary Supplements Translational Research Teams (RM1 Clinical Trial Required)
Closed Posted
- Opportunity number
- RFA-OD-24-014
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Up to $1,500,000
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- Small Businesses
- County Governments
- Public or Indian Housing Auth.
- State Governments
- Other
- Special District Governments
- 501(c)(3) Nonprofits
- Tribal Governments (Federally Recognized)
- Higher Education Inst. (Private)
- For Profit Organizations
- Higher Education Inst. (Public)
- Tribal Organizations (Not Federally Recognized)
- Non-501(c)(3) Nonprofits
- City/Township Governments
- Independent School Districts
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Department of Health and Human Services National Institutes of Health is offering a grant opportunity to support collaborative, transdisciplinary research teams investigating botanical and other natural products relevant to dietary supplements. The goal is to advance promising, chemically complex natural products towards highly informative clinical trials that measure their effects on quantitative, objective markers of human resilience. Eligible applicants include a wide range of organizations, such as small businesses, governments, nonprofits, and higher education institutions. Projects must enhance workforce and institutional capacity to conduct rigorous research on these complex natural products. Proposals will be evaluated on criteria including scientific merit, team expertise, and plans for future clinical efficacy trials.
This grant opportunity is part of the Consortium Advancing Research on Botanicals and Other Natural Products (CARBON) Program, which includes related funding opportunities focused on leveraging data and natural product nuclear magnetic resonance research. The expected duration of awarded projects is not specified, but the Notice states that accomplishing the grant's aims should provide a strong foundation for future proposed clinical efficacy trials on the effects of natural products on resilience.
Synopsis
2 versions
Update #2 · Latest ·
The purpose of this Notice of Funding Opportunity (NOFO) is to support collaborative, transdisciplinary, translational research projects which advance exceptionally promising, chemically complex botanical and other natural products relevant to dietary supplements towards highly informative clinical trials of their effects on quantitative, objective measures of human resilience. Dynamic, synergistic interactions among the range of experts required to ensure rigor in all aspects of this research will be supported by a multi-PD/PI team collaborating on a single set of integrated specific aims, culminating in data on optimal parameters for a future proposed clinical efficacy trial, as well as the development and validation of other critical knowledge and methods for interpretation of such a trial, such as clinical assessment of the engagement of an outcome-relevant target. Enhancing workforce and institutional capacity to conduct future rigorous, transdisciplinary research on chemically complex natural products must be built into the plans for research and for enhancing diverse perspectives. Achievement of the RM1 specific aims is expected to provide a strong foundation for a future highly informative clinical efficacy trial of the effects on resilience of a chemically complex natural product.This NOFO is one component of the Consortium Advancing Research on Botanicals and Other Natural Products (CARBON) Program. Other components of this Program include RFA-AT-24-008, Leveraging Data at Scale to Understand Natural Product Impacts on Whole Person Health (R01) and RFA-AT-24-007, Limited Competition: Research Resource for Natural Product Nuclear Magnetic Resonance Data (R24).
Update #1 ·
The purpose of this Notice of Funding Opportunity (NOFO) is to support collaborative, transdisciplinary, translational research projects which advance exceptionally promising, chemically complex botanical and other natural products relevant to dietary supplements towards highly informative clinical trials of their effects on quantitative, objective measures of human resilience. Dynamic, synergistic interactions among the range of experts required to ensure rigor in all aspects of this research will be supported by a multi-PD/PI team collaborating on a single set of integrated specific aims, culminating in data on optimal parameters for a future proposed clinical efficacy trial, as well as the development and validation of other critical knowledge and methods for interpretation of such a trial, such as clinical assessment of the engagement of an outcome-relevant target. Enhancing workforce and institutional capacity to conduct future rigorous, transdisciplinary research on chemically complex natural products must be built into the plans for research and for enhancing diverse perspectives. Achievement of the RM1 specific aims is expected to provide a strong foundation for a future highly informative clinical efficacy trial of the effects on resilience of a chemically complex natural product. This NOFO is one component of the Consortium Advancing Research on Botanicals and Other Natural Products (CARBON) Program. Other components of this Program include RFA-AT-24-008, Leveraging Data at Scale to Understand Natural Product Impacts on Whole Person Health (R01) and RFA-AT-24-007, Limited Competition: Research Resource for Natural Product Nuclear Magnetic Resonance Data (R24).
Files
| File | Type | Posted |
|---|---|---|
| RFA-OD-24-014-Full-Announcement.html | HTML file |
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