Zeiss Sigma 3View Service Contract with 3 Option years

Closed Pre-Solicitation Posted

Solicitation number
75N98026Q00729
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
Bethesda, Maryland 20892, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institutes of Health, National Institute on Biomedical Imaging and Bioengineering (NIBIB) intends to solicit a service contract for maintenance and parts support on a Zeiss SIGMA-VP scanning electron microscope equipped with 3View serial-section imaging capability, with response due by July 13, 2026.

The contract will cover three option years. NIBIB operates the instrument at its BEPS Shared Resource facility in support of serial block face imaging research across multiple NIH institutes and centers, including NINDS, NICHD, NHLBI, NCI, NIDDK, NIDCD, and NEI. The microscope is used to visualize three-dimensional cellular and tissue structures, including endocrine tissues (pancreatic islet cells and capillaries), neuronal retina tissue, cochlear inner ear tissue, and blood platelet structures.

The 3View system performs in situ cutting of serial plastic sections at 25 nanometer thickness or finer while imaging with a highly sensitive detector. NIBIB states that only experienced Zeiss engineers can service the equipment, provide replacement parts, or advise on usage, and that remote troubleshooting support from Zeiss engineers is critical to research continuity. The agency notes that ad hoc service calls without a service contract incur substantially higher costs.

Place of performance is Bethesda, Maryland. No set-aside is anticipated. The PSC is J066 (Maint/Repair/Rebuild of Equipment—Instruments and Laboratory Equipment); NAICS 811210 (Electronic and Precision Equipment Repair and Maintenance).

Notice text

The National Institute on Biomedical Imaging and Bioengineering (NIBIB), Laboratory of Cellular Imaging and Macromolecular Biophysics (LCIMB), Cellular and Supramolecular Structure and Function (CSSF) Section requires a service contract for the Zeiss SIGMA-VP scanning electron microscope (SEM) with a variable pressure (VP) capability and with the 3View capabilities. The 3View system allows us to perform insitu cutting of at least 25 nm serial plastic sections while imaging with a special highly sensitive detector in the SEM. The data acquired by this technique is used to visualize cellular structures and organelles in 3D, which is one of the most desired methods used by our collaborators. Only experienced Zeiss engineer can service this equipment, provide the parts or advice on the usage. We also depend on Zeiss engineers to assist us when the problem is resolvable remotely. To have Zeiss engineer arrive, service the equipment and provide new parts on site without this service contract will cost us significantly higher.

Researchers across the NIH are using the Zeiss SIGMA-VP scanning electron microscope (SEM) with a variable pressure (VP) capability with 3View capabilities.  This instrument is situated in NIBIB’s BEPS Shared Resource, where it is used to study the three-dimensional structure of cells and tissues using the serial block face (SBF) imaging technique using an ultramicrotome built into the specimen chamber of the SEM. The research enabled by the 3View SIGMA SEM includes the three-dimensional structure determination of (1) endocrine tissues including insulin-secreting beta cells and glucagon-secreting alpha cells as well as micro-capillaries in pancreatic islets of Langerhans, (2) neuronal tissues of the retina, and (3) cochlear tissues of the inner ear (4) blood platelet basic structural characterization, etc.  The instrument is used by scientists in many NIH institutes and centers including: NIBIB, NINDS, NICHD, NHLBI, NCI, NIDDK, NIDCD, and NEI as well as extramurally. It is essential to keep the instrument running at the highest level of performance.

1. Protect premium SIGMA System

2. Protect premium VP FESEM/XB

3. Protect premium 3View

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