Ultra-high performance liquid chromatography (UPLC) system for a Thermo Scientific Q-Exactive (QE) to support method development for economic adulteration

Closed Pre-Solicitation Posted

Solicitation number
HFP-2025-129689
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
College Park, Maryland 20740, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The Food and Drug Administration's Office of Chemistry and Toxicology seeks to procure an ultra-high performance liquid chromatography (UPLC) system for their Division of Analytical Chemistry to develop methods for analyzing contaminants and economic adulteration in foods, including polyfluoroalkyl substances (PFAS). This market research solicitation requires one UPLC system with an option for two additional systems, specifically designed to be compatible with existing Sciex mass spectrometers and a Thermo Scientific Q-Exactive HF Orbitrap. The system must include a dual binary pump LC system, autosampler, temperature-controlled column oven, and compatibility with current software platforms. Interested contractors must submit capability statements demonstrating technical capabilities, three years of past performance references, delivery capabilities, and respondent overview information. The response deadline is July 24, 2025, at 1:00 PM Central Time, with particular encouragement for small business participation.

This procurement operates under NAICS code 334516 for Analytical Laboratory Instrument Manufacturing with a small business size standard of 1,000 employees and carries no set-aside designation. The system will be delivered to the FDA/HFP laboratory in College Park, Maryland, and must include a one-year warranty, installation services, compatibility verification, and a one-day on-site training program for FDA users. While specific award values are not disclosed in this sources sought notice, the procurement involves a base requirement for one UPLC system with options for two additional identical systems. The equipment will serve as an inlet for previously purchased mass spectrometry equipment and support the FDA's food safety mission through comprehensive contamination analysis methods. No incumbent contractors or current service providers are identified in the documentation.

Notice text

See attached sources sought notice. The purpose of this requirement is to purchase a liquid chromatograph (LC) system for the Office of Laboratory Operations and Applied Science (OLOAS), Office of Chemistry and Toxicology (OCT), Division of Analytical Chemistry (DAC), and Method Development Branch (MDB).

This need is to develop new methods that will be applicable for the Food and Drug Administration (FDA) laboratories dedicated to food safety. This instrumentation will be used to develop comprehensive methods for the analysis of contaminants in foods and rapidly analyze many samples to determine contamination. The instruments will serve as an inlet for previously purchased Sciex mass spectrometers as well as a Thermo Scientific Q-Exactive HF Orbitrap (QE-HF). 

Files

File Type Posted
Sources Sought Notice HFP-2025-129689.pdf PDF

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